Clinical Trials for Anal Cancer

Find clinical trials for anal cancer. Discover research opportunities and treatment options in your area.

41 Active Trials Found

Showing 41 trials on this page

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A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers

NCT ID: NCT05544929

This clinical trial is exploring the safety and effectiveness of a new treatment called KFA115, both on its own and in combination with another medication called pembrolizumab, for patients with ce...

Recruiting

Phase: PHASE1 Type: interventional Locations: Toronto, Ontario, Canada, Pittsburgh, Pennsylvania, United States +24 more

Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)

NCT ID: NCT02628067

This clinical trial is studying a medication called pembrolizumab (MK-3475) for people with advanced solid tumors that have not responded to standard treatments. The trial aims to see how well this...

Recruiting

Phase: PHASE2 Type: interventional Locations: North Ryde, , Australia, Midrand, , South Africa +29 more

Screening for Anal Cancer in Men Who Have Sex With Men Using Pre-Exposure Prophylaxis

NCT ID: NCT07029152

This study is looking at anal cancer risk in men who have sex with men (MSM) who are taking a medicine called PrEP to prevent HIV infection. The researchers want to find out how common certain earl...

Not yet recruiting

Phase: NA Type: interventional Locations: Gent, , Belgium, Leuven, , Belgium +5 more

Integrated Cancer Repository for Cancer Research

NCT ID: NCT02012699

The Integrated Cancer Repository for Cancer Research (iCaRe2) is a study designed to gather important information and samples from adults who have been diagnosed with cancer, those at high risk for...

Recruiting

Type: observational Locations: Pittsburgh, Pennsylvania, United States, Denver, Colorado, United States +93 more

Study of Pembrolizumab, Carboplatin, Paclitaxel, and Radiation for the Treatment of Early-Stage Anal Cancer

NCT ID: NCT06493019

This clinical trial is studying a new treatment approach for early-stage anal cancer using a combination of four therapies: pembrolizumab (an immunotherapy drug), carboplatin and paclitaxel (chemot...

Recruiting

Phase: PHASE2 Type: interventional Locations: Baltimore, Maryland, United States, New Brunswick, New Jersey, United States +1 more

Screening for Anal Cancer in Women With High-grade Vulvar Dysplasia or Vulvar Cancer.

NCT ID: NCT03061435

This clinical trial is focused on screening for anal cancer in women who have been diagnosed with certain vulvar conditions, specifically those with high-grade vulvar dysplasia or vulvar cancer. Re...

Recruiting

Phase: NA Type: interventional Locations: Toronto, Ontario, Canada

EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.

NCT ID: NCT06263088

The EQUITY GI clinical trial is designed to improve the care of Black patients diagnosed with various types of gastrointestinal (GI) cancers, such as colon, rectal, pancreatic, and stomach cancer. ...

Recruiting

Phase: NA Type: interventional Locations: Cleveland, Ohio, United States

Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women

NCT ID: NCT06904365

This clinical trial is looking at a new way to protect the ovaries of young women who need radiation therapy for certain cancers, such as uterine or rectal cancer. Many women under 50 are facing th...

Recruiting

Type: observational Locations: Saint Louis, Missouri, United States

REDEL Trial: Reduced Elective Nodal Dose for Anal Cancer Toxicity Mitigation

NCT ID: NCT05902533

The REDEL Trial is a clinical study looking at how a lower dose of radiation to nearby lymph nodes can help reduce side effects in patients with anal cancer who are also receiving chemotherapy and ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Columbus, Ohio, United States, Burlington, Vermont, United States +1 more

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers

NCT ID: NCT05639972

This clinical trial is exploring a new treatment called E7 T-cell receptor (TCR) T-cell therapy for patients with advanced cancers linked to the human papillomavirus (HPV), such as cervical and thr...

Recruiting

Phase: PHASE1 Type: interventional Locations: New Brunswick, New Jersey, United States, New Brunswick, New Jersey, United States +1 more

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

NCT ID: NCT05686226

This clinical trial is exploring a new type of immunotherapy called E7 TCR-T cell therapy for patients with certain cancers linked to the human papillomavirus (HPV), such as cervical, throat, and a...

Recruiting

Phase: PHASE2 Type: interventional Locations: New Brunswick, New Jersey, United States, New Brunswick, New Jersey, United States +1 more

ASSESSING THE GAY MALE EXPERIENCE WITH ANAL CANCER PREVENTION STRATEGIES

NCT ID: NCT05628194

This clinical trial is called "Assessing the Gay Male Experience with Anal Cancer Prevention Strategies." It aims to understand how men who have sex with men (MSM) feel about anal cancer screening ...

Recruiting

Type: observational Locations: Minneapolis, Minnesota, United States, Minneapolis, Minnesota, United States

Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors

NCT ID: NCT04157985

This clinical trial is studying the best length of treatment with a type of cancer therapy called PD-1/PD-L1 inhibitors, which are used for various advanced solid tumors, including lung, bladder, a...

Recruiting

Phase: PHASE3 Type: interventional Locations: Pittsburgh, Pennsylvania, United States

A Study Regarding Tissue Response During and After Treatment for Anal Cancer

NCT ID: NCT05939401

This clinical trial is focused on understanding how anal cancer responds to treatment. Researchers want to learn more about the tumor's environment, how the cancer interacts with immune cells, and ...

Recruiting

Type: observational Locations: Gothenburg, , Sweden, Gothenburg, , Sweden

A Phase III Trial to Evaluate the Efficacy, Immunogenicity and Safety of a Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.Coli) in Chinese Males

NCT ID: NCT06866574

This clinical trial is looking at a new vaccine designed to protect against various types of human papillomavirus (HPV), which can cause issues like genital warts and certain cancers in men. The tr...

Not yet recruiting

Phase: PHASE3 Type: interventional Locations: Chengdu, Sichuan, China, Hangzhou, Zhejiang, China +2 more

Phase III Study Evaluating Induction Chemotherapy Followed by Chemoradiotherapy Compared to Standard Chemoradiotherapy for Locally Advanced SCCA

NCT ID: NCT06207981

This clinical trial is studying a new treatment approach for patients with locally advanced anal cancer, specifically squamous cell carcinoma. The trial compares two methods: one that uses a combin...

Recruiting

Phase: PHASE3 Type: interventional Locations: Bordeaux, , France

Identification of Molecular Signatures of High-risk Oncogenic HPV and Study of Their Associations With the Presence of High-grade Lesions and/or Anal Cancer 10 Years After Inclusion in the ANRS IPERGAY Trial

NCT ID: NCT06522256

The HPVsign study is looking to understand how certain types of the human papillomavirus (HPV), which can lead to serious health issues like high-grade lesions and anal cancer, affect people over t...

Not yet recruiting

Phase: NA Type: interventional Locations: Lyon, , France, Paris, , France +1 more

Host Genome Methylation: a Screening Tool in Anal Cancer Detection

NCT ID: NCT06792604

This clinical trial is looking at new ways to help detect anal cancer in certain at-risk groups using specific biological markers found in anal samples. The study is based on recent guidelines that...

Recruiting

Phase: NA Type: interventional Locations: Paris, Ile De France, France, Paris, île De France, France +15 more

Multidimensional Examination of Patients with Colorectal and Anal Cancer

NCT ID: NCT06562140

This clinical trial is looking at how physical activity, functional ability, and overall health are affected in people with colorectal and anal cancer. The researchers are especially interested in ...

Recruiting

Type: observational Locations: Pécs, Baranya, Hungary

HPV Genotype Attribution and Disease Burden of Anal Cancer in China

NCT ID: NCT06670495

This clinical trial, titled "HPV Genotype Attribution and Disease Burden of Anal Cancer in China," aims to learn more about the human papillomavirus (HPV) and its connection to anal cancer in China...

Not yet recruiting

Type: observational

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