Clinical Trials for Aortic Stenosis

CAN3T - Canadian TAVI Triage Tool

NCT ID: NCT06551610

The CAN3T trial is investigating a new tool designed to help patients with aortic stenosis who are waiting for a TAVI (transcatheter aortic valve implantation) procedure. This study aims to find ou...

Loss of Y Chromosome in Aortic Stenosis

NCT ID: NCT06595407

This clinical trial is studying a heart condition called aortic stenosis, which is a narrowing of the heart valve that makes it harder for the heart to pump blood to the body. This condition is esp...

Comparison of Self- and Balloon-expandable Valves in Patients With Ascending Aortic Dilation Undergoing Transcatheter Aortic Valve Replacement: The AAD-CHOICE

NCT ID: NCT06009588

The AAD-CHOICE trial is a study comparing two types of heart valves—self-expandable and balloon-expandable—used during a procedure called transcatheter aortic valve replacement (TAVR). This trial f...

High-Sensitivity Troponin T Plasma Levels in Patients With Aortic Stenosis (Tyrolean Aortic Stenosis Study-2)

NCT ID: NCT02448485

The Tyrolean Aortic Stenosis Study-2 (TASS-2) is a clinical trial that is looking at a heart protein called troponin T in patients with a condition known as aortic stenosis. Aortic stenosis occurs ...

Reversibility of Cardiac Conduction Disturbances Following TAVI

NCT ID: NCT06481137

This clinical trial is studying how heart conduction problems might change after a procedure called transcatheter aortic valve implantation (TAVI), which is used to treat a condition known as aorti...

Feasibility, Safety, and Effectiveness of the ACURATE neo2 Transcatheter Heart Valve for Severe Bicuspid Aortic Stenosis

NCT ID: NCT06212050

Fibrosis in Chronic and Delayed Myocardial Infarction

NCT ID: NCT05756608

This clinical trial is investigating how fibrosis, a condition where the heart muscle becomes stiff due to injury, affects various heart-related illnesses like aortic stenosis (narrowing of the hea...

PARTNER 3 Trial - Aortic Valve-in-Valve

NCT ID: NCT03003299

The PARTNER 3 Trial is studying a new heart valve called the SAPIEN 3/SAPIEN 3 Ultra, which is designed for patients who have a failing aortic bioprosthetic valve. A bioprosthetic valve is a type o...

Effect of PCSK9 Inhibitors on Calcific Aortic Valve Stenosis

NCT ID: NCT04968509

This clinical trial is studying the effects of a new type of medication called PCSK9 inhibitors on a heart condition known as calcific aortic stenosis (CAS), which can lead to serious heart issues....

Dobutamine Stress Echocardiography in LF/LG Aortic Stenosis and Wild-type Transthyretin Amyloid Cardiomyopathy

NCT ID: NCT06372301

This clinical trial is studying how well a specific heart test called dobutamine stress echocardiography can help doctors understand the severity of aortic stenosis (a condition where the heart's a...

Evaluating Infrasonic Hemodynography

NCT ID: NCT04636892

This clinical trial is studying a new, noninvasive device that can be worn to help doctors better understand how well the heart and blood vessels are working. Specifically, it aims to see how accur...

EffecTAVI Registry

NCT ID: NCT05235555

The EffecTAVI Registry is a clinical trial that is studying the safety and effectiveness of a procedure called Transcatheter Aortic Valve Replacement (TAVI) for patients with severe aortic stenosis...

10-year Follow-up After Aortic Valve Replacement Surgery

NCT ID: NCT06255691

This clinical trial is looking at how patients feel and function ten years after having surgery to replace their aortic valve, a procedure done for a heart condition known as aortic stenosis. Resea...

PRogression Of bicuSPid-rElated aoRtOpathy in Patients Undergoing Transcatheter Aortic Valve Implantation (PROSPERO-TAVI)

NCT ID: NCT06248294

The PROSPERO-TAVI clinical trial is studying how a condition called bicuspid-related aortopathy (which often occurs in patients with a bicuspid aortic valve) progresses in patients who are treated ...

Phenotyping Heterogeneity and Regionality of the Aorta

NCT ID: NCT05603520

The clinical trial titled "Phenotyping Heterogeneity and Regionality of the Aorta" is studying how differences in the structure and function of the aorta—our body's main artery—affect conditions li...

Real-time Pressure Volume Loop Monitoring as a Guide for Enhanced Understanding of Changes in Elemental Cardiovascular Physiology During Therapeutic Strategies Aiming for Hemodynamic Optimization. Cohort II: Structural Heart Interventions (PLUTO-II)

NCT ID: NCT06204783

The PLUTO-II clinical trial is studying how a special tool called biventricular pressure-volume (PV) loop monitoring can help doctors better understand how the heart works during certain procedures...

Optimal Timing of Transcatheter Aortic Valve Implantation and Percutaneous Coronary Intervention - The TAVI PCI Trial

NCT ID: NCT04310046

The TAVI PCI Trial is studying the best timing for two important heart procedures in patients who have severe aortic stenosis (narrowing of the heart valve) and coronary artery disease (blockages i...

Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

NCT ID: NCT04634240

The COMPLETE TAVR study is investigating the best way to treat patients who have both severe aortic stenosis and coronary artery disease (CAD) when they undergo a procedure called transcatheter aor...

Functional and Quality of Life Improvement Following Transcatheter Heart Valve Implantation

NCT ID: NCT02023060

This clinical trial is looking to understand how patients feel and function after undergoing a procedure called transcatheter heart valve replacement. This procedure is often used for people with a...

Role of Aortic Valve Composition in Pathophysiology and Diagnosis of Aortic Stenosis

NCT ID: NCT06136689

This clinical trial is studying the aortic valve, which is a critical part of the heart that helps control blood flow. The goal is to understand how the composition of the aortic valve changes at d...