Clinical Trials for Aplastic Anemia

Find clinical trials for aplastic anemia. Discover research opportunities and treatment options in your area.

35 Active Trials Found

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A Study of Emapalumab for Pediatric Aplastic Anemia

NCT ID: NCT06430788

This clinical trial is studying a medication called emapalumab to see if it can help children and young adults with a condition known as severe Aplastic Anemia (sAA). Aplastic Anemia is a serious c...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Cincinnati, Ohio, United States +4 more

UI-Romi-02; Romiplostim Added to Standard of Care for Treatment Naive and Relapsed or Refractory Severe Aplastic Anemia

NCT ID: NCT07001254

The clinical trial titled UI-Romi-02 is studying the effects of a drug called romiplostim in treating severe aplastic anemia (SAA) in children and young adults. Aplastic anemia is a condition where...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Iowa City, Iowa, United States

Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell Transplantation in Older Adult Patients With Acquired Aplastic Anemia

NCT ID: NCT06752694

This clinical trial is studying the use of a medication called ruxolitinib to help prevent a condition known as graft versus host disease (GVHD) in older adults with acquired aplastic anemia. Aplas...

Recruiting

Phase: PHASE2 Type: interventional Locations: Seattle, Washington, United States

Reduced-Intensity Conditioning for the Prevention of Treatment-Related Mortality in Patients Who Undergo a Hematopoietic Stem Cell Transplant

NCT ID: NCT05031897

This clinical trial is studying a new way to prepare patients for a type of cancer treatment called hematopoietic stem cell transplant (HSCT). HSCT can help treat certain blood cancers, but sometim...

Recruiting

Phase: PHASE2 Type: interventional Locations: Philadelphia, Pennsylvania, United States

Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors

NCT ID: NCT05194397

This clinical trial is studying how exercise and a supplement called NR (which helps boost energy in cells) can improve fitness and muscle strength in young people aged 10 to 30 who have survived c...

Recruiting

Phase: PHASE2 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Memphis, Tennessee, United States +1 more

Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant

NCT ID: NCT03622788

This clinical trial is exploring a new treatment approach using special cells, called cytokine-treated veto cells, for patients with certain blood cancers after they have undergone a stem cell tran...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic Syndrome

NCT ID: NCT01624805

This clinical trial is exploring the use of a combination of medications to treat patients with aplastic anemia or a type of blood disorder called myelodysplastic syndrome. The medications being st...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Methadone as an Alternative Treatment for Children Underdoing HSCT

NCT ID: NCT06940570

This clinical trial is studying whether adding methadone, a type of pain medication, can help reduce pain in children aged 6 to 18 who are undergoing stem cell transplants for conditions like leuke...

Not yet recruiting

Phase: PHASE3 Type: interventional Locations: Dallas, Texas, United States

Reproductive and Mental Health of Patients With Aplastic Anemia

NCT ID: NCT06936930

This clinical trial is studying the reproductive and mental health of patients with aplastic anemia, a condition where the bone marrow doesn’t produce enough blood cells. While treatments for aplas...

Recruiting

Type: observational Locations: Tianjin, Tianjin, China

Study of CM313(SC) Injection in Subjects With Relapsed/Refractory Aplastic Anemia

NCT ID: NCT06791824

This clinical trial is studying a new treatment called CM313(SC) injection for patients with relapsed or refractory aplastic anemia, a serious condition where the bone marrow does not make enough b...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Tianjin, Tianjin, China

Revolade Tablets Specified Drug-use Survey

NCT ID: NCT06287268

This clinical trial is studying the use of a medication called eltrombopag in children and teenagers with aplastic anemia (AA), a condition where the body doesn’t make enough blood cells. The trial...

Recruiting

Type: observational Locations: Nagoya, Aichi, Japan, Osaka Sayama, Osaka, Japan +12 more

National Longitudinal Cohort of Hematological Diseases

NCT ID: NCT04645199

The National Longitudinal Cohort of Hematological Diseases study is looking to better understand various blood-related conditions, such as multiple myeloma, acute myeloid leukemia, and hemophilia, ...

Recruiting

Type: observational Locations: Tianjin, Tianjin, China

Standard Immunosuppressive Therapy Combined With Romiplostim N01 as First-line Treatment for Severe Aplastic Anemia

NCT ID: NCT06613880

This clinical trial is exploring a new treatment approach for severe aplastic anemia (SAA), a serious condition where the body doesn't produce enough blood cells. Researchers are studying a combina...

Recruiting

Phase: PHASE2 Type: interventional Locations: Tianjin, Tianjin, China

Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy

NCT ID: NCT06689800

The clinical trial titled "Let's Get REAL" is exploring a new tool designed to help families communicate better about decisions related to stem cell transplants and cellular therapies for children ...

Recruiting

Phase: NA Type: interventional Locations: Saint Louis, Missouri, United States

Indication of HSCT in Patients With Refractory/Relapse AA After First-line Standard Immunosuppressive Therapy Aged More Than 40 Years

NCT ID: NCT06646497

This clinical trial, called "APARR," is investigating a treatment option for adults over 40 years old who have severe aplastic anemia (SAA) that hasn’t improved with standard therapies. Aplastic an...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Paris, , France

Haploidentical HCT for Severe Aplastic Anemia

NCT ID: NCT04558736

This clinical trial is studying a new way to treat severe aplastic anemia (SAA), a serious condition where the bone marrow fails to produce enough blood cells. In this trial, patients will receive ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Memphis, Tennessee, United States

CD7 CAR-T Bridging to alloHSCT for Severe Aplastic Anemia

NCT ID: NCT06633328

This clinical trial is investigating a new treatment approach for patients with severe aplastic anemia, a serious condition where the bone marrow doesn't produce enough blood cells. The study is fo...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Hanzhou, Zhejiang, China

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

NCT ID: NCT06398457

This clinical trial is studying a new treatment called Darzalex Faspro (daratumumab and hyaluronidase-fihj) to see if it can help patients with high levels of donor-specific antibodies (DSA) who ar...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Baltimore, Maryland, United States

Umbilical Cord Blood Transplantation From Unrelated Donors

NCT ID: NCT03016806

This clinical trial is studying the use of umbilical cord blood stem cell transplantation as a treatment for various serious conditions such as acute leukemia, immune deficiency disorders, and cert...

Recruiting

Phase: PHASE1 Type: interventional Locations: Rochester, New York, United States

A Study of Romiplostim for the Treatment of Refractory Transfusion-dependent NSAA

NCT ID: NCT06535685

This clinical trial is investigating a medication called Romiplostim to see how well it works and how safe it is for patients with a condition known as refractory transfusion-dependent Non-Severe A...

Not yet recruiting

Phase: PHASE4 Type: interventional Locations: Beijing, Beijing, China

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