Clinical Trials for Atherosclerotic Cardiovascular Disease

The Belgian REAL (BE.REAL) Registry

NCT ID: NCT05726838

The Belgian REAL (BE.REAL) Registry is a clinical study aimed at understanding how well Inclisiran works in patients with Atherosclerotic Cardiovascular Disease (ASCVD). This condition involves the...

Lipoprotein(a) Levels in Patients With Atherosclerotic Cardiovascular Diseases in Russia

NCT ID: NCT06858332

This clinical trial is investigating the levels of a substance called Lipoprotein(a) or Lp(a) in patients with a type of heart disease known as atherosclerotic cardiovascular disease (ASCVD) in Rus...

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis

NCT ID: NCT05485961

This clinical trial is studying a medication called CSL300 (Clazakizumab) to see if it can help improve heart health for adults with end-stage kidney disease (ESKD) who are undergoing dialysis. The...

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

NCT ID: NCT07037433

This clinical trial is studying a medicine called maridebart cafraglutide to see if it can help people with heart disease who are also overweight or obese. Specifically, the trial wants to find out...

Study to Evaluate the Impact of a Targeted Lipid Optimization Program on LDL-C Control in At-risk Adult Patients With Dyslipidemia

NCT ID: NCT07034690

This clinical trial is studying a special program designed to help people with certain heart and blood vessel diseases better control their “bad” cholesterol, known as LDL cholesterol. The goal is ...

A Phase 1b Study to Assess the Safety, Tolerability, and Pharmacodynamics of AZD4144 in Participants With Established Atherosclerotic Cardiovascular and Chronic Kidney Disease.

NCT ID: NCT06675175

This clinical trial is investigating a new medication called AZD4144 to see how safe it is and how well it works in people with two specific health conditions: atherosclerotic cardiovascular diseas...

Fish Oil, Metformin and Heart Health in PCOS

NCT ID: NCT06424860

This clinical trial is exploring whether taking fish oil supplements can help improve heart health and insulin levels in women with Polycystic Ovary Syndrome (PCOS). Women with PCOS often have high...

A Pragmatic INitiative for LDL-C Management by a CLinical Pharmacist-Led Team Among Atherosclerotic CardiovascUlar DisEase Patients

NCT ID: NCT06571162

This clinical trial is looking at how a team of clinical pharmacists can help manage cholesterol levels, specifically LDL cholesterol (often referred to as "bad" cholesterol), in patients who have ...

Placebo-controlled Study of Single and Multiple Ascending Doses of UDP-003 in Healthy Human Participants and Patients

NCT ID: NCT06813339

This clinical trial is studying a new medication called UDP-003 to see if it is safe and effective for treating conditions related to heart disease, such as atherosclerotic cardiovascular disease a...

Clinical Implementation of Blood Pressure Polygenic Risk Score

NCT ID: NCT06962488

This clinical trial is studying how a special genetic test, called a polygenic risk score (PRS), can help people with high blood pressure (hypertension) improve their health. The trial will look at...

The Prevent Coronary Artery Disease Trial

NCT ID: NCT06494501

The Prevent Coronary Artery Disease Trial is a clinical study aimed at understanding whether closely managing heart-related risk factors in young adults can help reduce the buildup of artery plaque...

Pelacarsen Roll-over Extension Program

NCT ID: NCT06875973

The Pelacarsen Roll-over Extension Program is a clinical trial designed for people who have completed a previous study on a new treatment called pelacarsen (also known as TQJ230). This study aims t...

Coated or Chewable Aspirin and a Hybrid Strategy to Mitigate Adverse Effects of Air Pollution in Stable Atherosclerotic Disease

NCT ID: NCT06541691

This clinical trial is investigating the effectiveness and safety of two types of low-dose aspirin (enteric-coated and plain) in patients with atherosclerotic cardiovascular diseases, which include...

Long-term Follow-up of Participants Dosed with an Investigational Gene Editing Therapy for Cardiovascular Disease

NCT ID: NCT06112327

NOTIFY (New Observations Taking Information From Yesterday)

NCT ID: NCT05977413

The NOTIFY trial is studying whether informing patients and their doctors about a specific finding on a low-dose CT scan—called coronary artery calcium—can help prevent serious heart-related proble...

Effects of Ezetimibe Combination Therapy for Patients With Atherosclerotic Cardiovascular Disease; Randomized Comparison of LDL-cholesterol Targeting <70 Versus <55mg/dL; Ez-PAVE Trial

NCT ID: NCT04626973

The Ez-PAVE Trial is studying how effective a combination therapy of ezetimibe and statins can be for patients with atherosclerotic cardiovascular disease (ASCVD). The goal is to see if targeting l...

Immunomodulatory Effects of PCSK9 Inhibition

NCT ID: NCT05720156

This clinical trial is studying the effects of a new type of medication called PCSK9 inhibitors on inflammation in patients with atherosclerotic cardiovascular disease (ASCVD), which is a condition...

Study on the Composite Endpoint Event of PCSK9 Inhibitor in Patients With Very High Risk of ASCVD and Cancer

NCT ID: NCT05976893

This clinical trial is looking at a medication called a PCSK9 inhibitor to see how it affects patients who have a very high risk of serious heart problems (known as atherosclerotic cardiovascular d...

LDL Cholesterol TARGETs in OLDer Patients (Age≥75 Years) With ASCVD (TARGET OLD)

NCT ID: NCT05765370

The TARGET OLD clinical trial is investigating the best way to lower cholesterol levels in older patients aged 75 and above who have a history of heart and blood vessel diseases, known as atheroscl...

Atherosclerotic Cardiovascular Risk in Childhood and Teen-age Onset Diabetes

NCT ID: NCT05294653

This clinical trial is looking at how diabetes in children and teenagers can lead to heart and blood vessel problems, known as atherosclerotic cardiovascular disease (ASCVD). Researchers want to un...