Clinical Trials for Brain Cancer

A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2

NCT ID: NCT03152318

This clinical trial is studying a new treatment for patients with recurrent malignant glioma, a type of brain cancer. The treatment involves an investigational drug called rQNestin34.5v.2, which is...

A Virtually Delivered Exercise Intervention To Mitigate Cognitive Deficits From Radiotherapy In AYAs With Brain Tumors

NCT ID: NCT05554159

This clinical trial is looking at a new virtual exercise program designed to help young people aged 15 to 39 who have brain tumors and are about to start treatment with cranial radiotherapy. The go...

Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer

NCT ID: NCT06058988

This clinical trial is investigating a new treatment called trastuzumab deruxtecan (T-DXd) for people with certain types of brain cancer, including glioblastoma and metastatic cancers that express ...

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

NCT ID: NCT06991101

This clinical trial is investigating a new approach for treating newly diagnosed glioblastoma, a type of aggressive brain cancer. Specifically, the study is testing whether adding a drug called rux...

18F-Fluciclovine PET Amino Acid Evaluation of Brain Metastasis Treated With Stereotactic Radiosurgery

NCT ID: NCT06048094

This clinical trial is looking at a new way to see how well treatment works for patients with brain cancer that has spread to the brain, known as brain metastases. Specifically, the study is testin...

HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)

NCT ID: NCT06930846

The HOBSCOTCH-CA trial is studying a program designed to help improve the quality of life and cognitive abilities of people who have survived brain cancer or brain tumors. This includes various typ...

Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent

NCT ID: NCT06322342

This clinical trial is testing a new MRI contrast agent called RVP-001, which is made from manganese, to see how safe and effective it is for patients with certain brain conditions, such as brain t...

Head Stabilization in Whole Brain RT

NCT ID: NCT06776406

This clinical trial is focused on improving the way patients' heads are stabilized during whole brain radiation therapy, which is a treatment for brain cancer. Researchers are developing a new syst...

Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA

NCT ID: NCT02800486

This clinical trial is studying a new treatment approach for patients with certain types of brain tumors, specifically recurrent glioblastoma, anaplastic astrocytoma, and anaplastic oligoastrocytom...

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

NCT ID: NCT02861898

This clinical trial is studying a new way to treat newly diagnosed glioblastoma (GBM), a serious type of brain cancer. Researchers are testing a drug called Cetuximab (CTX), which targets a specifi...

Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM

NCT ID: NCT03213002

This clinical trial is studying a new treatment approach for patients with newly diagnosed glioblastoma multiforme (GBM), a type of aggressive brain cancer. The researchers want to see if combining...

HRQoL in Patients with Solid Tumors Treated with Hadrontherapy

NCT ID: NCT05947149

This clinical trial is studying the quality of life in patients with head and neck, skull base, and brain cancers who are treated with a specialized cancer treatment called hadrontherapy. The resea...

Anesthesia Induced Brain Cancer Survival (ABC Survival): A Feasibility Study

NCT ID: NCT04962672

The ABC Survival trial is studying how different types of anesthesia used during brain surgery might affect the survival of patients with high-grade brain tumors, specifically glioblastoma multifor...

Immunogene-modified T (IgT) Cells Against Glioblastoma Multiforme

NCT ID: NCT03170141

Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic Radiosurgery

NCT ID: NCT04689048

This clinical trial is investigating a new imaging agent called 18F-fluciclovine to see how well it can detect which patients with large brain metastases are responding to a specific type of radiat...

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

NCT ID: NCT05686798

This clinical trial is investigating a new treatment approach for patients with a type of brain cancer called high-grade astrocytoma, which often comes back after initial treatment. The researchers...

A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas

NCT ID: NCT04745156

This clinical trial is exploring a new approach to help patients with low-grade gliomas, a type of brain tumor, during surgery. The study uses a special device that stimulates the brain while a pat...

A Study to Measure the Effect of Brain Stimulation on Hand Strength and Function in Patients with Brain Tumors

NCT ID: NCT05023434

This clinical trial is studying how brain stimulation might improve hand strength and function in patients who have brain tumors that affect the part of the brain responsible for hand movement. Dur...

TIL Therapy Combined With Pembrolizumab for Advanced Brain Cancer Including Gliomas and Meningiomas

NCT ID: NCT06640582

This clinical trial is studying a new treatment approach for patients with advanced brain cancer, including types like gliomas and meningiomas. The trial is testing a method called tumor-infiltrati...

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

NCT ID: NCT04899908

This clinical trial is studying a new treatment approach for patients with brain metastases, which are cancerous growths that have spread to the brain from other parts of the body. Researchers want...