Clinical Trials for Clear Cell Renal Cell Carcinoma

Find clinical trials for clear cell renal cell carcinoma. Discover research opportunities and treatment options in your area.

36 Active Trials Found

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Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL Study

NCT ID: NCT04071223

The RadiCaL Study is a clinical trial investigating whether adding a new anti-cancer drug called radium-223 dichloride to the usual treatment, cabozantinib, can help patients with advanced renal ce...

Recruiting

Phase: PHASE2 Type: interventional Locations: Durham, North Carolina, United States, Milwaukee, Wisconsin, United States +49 more

Belzutifan's Role in Active Surveillance Versus Treatment for Indolentmetastatic Clear Cell Renal Ccell Carcinoma (BRAVE-RCC)

NCT ID: NCT07023432

This clinical trial is studying a medication called belzutifan to see if it can help control a type of kidney cancer called clear cell renal cell carcinoma (ccRCC) that has spread to other parts of...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

An Investigational Scan (89Zr-DFO-GmAb PET/CT) Compared to Contrast-Enhanced CT for the Detection of Recurrent Clear Cell Renal Cell Cancer After Surgery Comparing Carbonic Anhydrase IX (CAIX) PET CT to Conventional PET CT for Post-Op Staging in Kidney Cancer

NCT ID: NCT06447103

This clinical trial is studying a new imaging test called 89Zr-DFO-GmAb PET/CT to see if it is better than the standard contrast-enhanced CT in finding recurrent clear cell renal cell cancer after ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Los Angeles, California, United States

Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors

NCT ID: NCT03682289

This clinical trial is investigating a new treatment called Ceralasertib (AZD6738) for patients with various types of solid tumors, including kidney cancer, pancreatic cancer, and endometrial cance...

Recruiting

Phase: PHASE2 Type: interventional Locations: San Francisco, California, United States, Duarte, California, United States +1 more

A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit

NCT ID: NCT06805825

This clinical trial is studying a new medication called NN3201, which is designed to treat patients with advanced or metastatic solid tumors that express a protein called c-Kit. These tumors can in...

Recruiting

Phase: PHASE1 Type: interventional Locations: Portland, Oregon, United States, Houston, Texas, United States +3 more

Trial of XL092 in Combination With Immunotherapy in Patients Who Progress on Adjuvant Therapy in Clear Cell RCC

NCT ID: NCT06863311

This clinical trial is investigating a new treatment for patients with advanced clear cell renal cell carcinoma (RCC), a type of kidney cancer, who have not responded to the current standard treatm...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

NCT ID: NCT05536141

This clinical trial is studying a new treatment called casdatifan for people with advanced solid tumors, specifically focusing on clear cell renal cell carcinoma (ccRCC), which is a type of kidney ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Birmingham, Alabama, United States, Box Hill, Victoria, Australia +38 more

Contrast-enhanced CT-based Deep Learning Model for Preoperative Prediction of Disease-free Survival (DFS) in Localized Clear Cell Renal Cell Carcinoma (ccRCC)

NCT ID: NCT06088134

This clinical trial is studying a new way to predict how long patients with localized clear cell renal cell carcinoma (ccRCC) might remain free from disease after surgery. Researchers are using adv...

Recruiting

Type: observational Locations: Chongqing, Chongqing, China

Study of Adaptive Immunotherapy With VEGFR-TKI in Patients With Advanced RCC

NCT ID: NCT06860386

This clinical trial is studying a new treatment approach using a combination of two medications, pembrolizumab and axitinib, for patients with advanced clear cell renal cell carcinoma (a type of ki...

Recruiting

Phase: PHASE2 Type: interventional Locations: Tampa, Florida, United States

Observational Basket Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic Platform

NCT ID: NCT05520099

This clinical trial is studying a new diagnostic tool called the Cybrid live tumor diagnostic platform, which aims to help doctors better understand and predict how solid tumors, like certain cance...

Recruiting

Type: observational Locations: Orlando, Florida, United States, Madison, Wisconsin, United States +9 more

A Beta-only IL-2 ImmunoTherapY Study

NCT ID: NCT05086692

This clinical trial, called the Beta-only IL-2 ImmunoTherapY Study, is looking to test a new treatment called MDNA11 for patients with advanced solid tumors, which are types of cancer that have spr...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Diego, California, United States, Baltimore, Maryland, United States +28 more

Study of Nivolumab in Combination With 177Lu-girentuximab for Kidney Cancer

NCT ID: NCT05239533

This clinical trial is investigating a new treatment option for patients with advanced clear cell renal cell carcinoma (ccRCC), a type of kidney cancer. The treatment combines two drugs: 177Lu-gire...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Basking Ridge, New Jersey, United States +7 more

Immune PET and Proteomics for the Assessment of Response to Spatially Fractionated or Palliative Radiotherapy With or Without Immunotherapy

NCT ID: NCT06976021

This clinical trial is studying new ways to measure how well certain cancer treatments work, specifically for patients with advanced cancers like triple negative breast cancer, cervical cancer, mel...

Not yet recruiting

Phase: PHASE2 Type: interventional

Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors

NCT ID: NCT04374877

This clinical trial is studying a new treatment called CHS-388, which is a type of medication known as a monoclonal antibody. This treatment specifically targets a substance in the body called IL-2...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States, Boston, Massachusetts, United States +22 more

Overtaking Intra and Inter Tumoral Heterogeneity In Von Hippel-Lindau Related Renal Cancer

NCT ID: NCT06195150

This clinical trial is studying a type of kidney cancer known as clear cell renal cell carcinoma (ccRCC) in patients with a genetic condition called von Hippel-Lindau (VHL) syndrome. The researcher...

Recruiting

Type: observational Locations: Milan, Lombardy, Italy

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

NCT ID: NCT06661720

This clinical trial is studying whether adding a drug called tivozanib to the standard treatment, pembrolizumab, can improve outcomes for patients with certain types of kidney cancer, specifically ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Saint Louis, Missouri, United States, Flint, Michigan, United States +60 more

Seleno-L Methionine (SLM)-Axitinib-Pembrolizumab

NCT ID: NCT05363631

This clinical trial is studying a new combination treatment for patients with advanced clear cell renal cell carcinoma (ccRCC), which is a type of kidney cancer. The researchers want to see if addi...

Recruiting

Phase: PHASE1 Type: interventional Locations: Iowa City, Iowa, United States

68Ga-NYM096/177Lu-NYM096 in Metastatic ccRCC

NCT ID: NCT06649682

This clinical trial is studying a new imaging and treatment approach for patients with metastatic clear cell renal cell carcinoma (ccRCC), which is a type of kidney cancer that has spread to other ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, Beijing, China

A Study of MGC026 in Participants With Advanced Solid Tumors

NCT ID: NCT06242470

This clinical trial is investigating a new treatment called MGC026 for adults with advanced solid tumors, which are types of cancer that have spread or cannot be removed through surgery. The study ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States, Los Angeles, California, United States +10 more

Phase 1b/2 Study of Combination 177Lu Girentuximab Plus Cabozantinib and Nivolumab in Treatment naïve Patients With Advanced Clear Cell RCC

NCT ID: NCT05663710

This clinical trial is investigating a new treatment approach for patients with advanced clear cell renal cell carcinoma (ccRCC), a type of kidney cancer. The study is looking at whether combining ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

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