Clinical Trials for Colorectal Cancer Metastatic

Find clinical trials for colorectal cancer metastatic. Discover research opportunities and treatment options in your area.

64 Active Trials Found

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Naptumomab Estafenatox in Combination with Durvalumab in Subjects with Selected Advanced or Metastatic Solid Tumor, Including a Cohort Expansion in Esophageal Cancer.

NCT ID: NCT03983954

This clinical trial is investigating a new treatment approach for patients with advanced or metastatic solid tumors, including types of cancer such as breast, ovarian, pancreatic, and esophageal ca...

Recruiting

Phase: PHASE1 Type: interventional Locations: Ramat Gan, , Israel, Petah Tikva, , Israel +7 more

Irinotecan Liposomes Combined with Cetuximab + Vermofenib in First-line Failure of Advanced Colorectal Cancer

NCT ID: NCT06763029

This clinical trial is investigating a new treatment approach for patients with advanced colorectal cancer that has not responded to initial therapies. The study is looking at the effectiveness and...

Recruiting

Phase: PHASE2 Type: interventional Locations: Shanghai, Shanghai, China

Efficacy and Safety of Tunlametinib Plus Vemurafenib in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer

NCT ID: NCT06008119

The clinical trial titled "Efficacy and Safety of Tunlametinib Plus Vemurafenib in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer" is exploring a new treatment combination for patient...

Recruiting

Phase: PHASE3 Type: interventional Locations: Beijing, Beijing, China

Cryoablation Combined with Sintilimab Plus Regorafenib in Previously Treated Colorectal Cancer Liver Metastasis

NCT ID: NCT05057052

This clinical trial is exploring a new treatment approach for patients who have colorectal cancer that has spread to the liver. It combines a procedure called cryoablation, which destroys cancer ce...

Recruiting

Phase: PHASE2 Type: interventional Locations: Shanghai, Shanghai, China, Shanghai, Shanghai, China

Efficacy and Safety of Chemotherapy With XELOX (Oxaliplatin + Capecitabine) and Bevacizumab in Combination With Adebrelimab in First-line Treatment of Microsatellite Stable (MSS) Initially Unresectable Metastatic Colorectal Cancer

NCT ID: NCT06282445

This clinical trial is studying a new treatment approach for patients with advanced colorectal cancer that cannot be removed by surgery. The treatment combines chemotherapy (XELOX, which includes t...

Recruiting

Phase: PHASE2 Type: interventional Locations: Jinhua, Zhejiang, China

Regorafenib and Sintilimab in Combination with Electroacupuncture in MSS CRC

NCT ID: NCT06456515

This clinical trial is studying a new treatment approach for patients with advanced colorectal cancer that has not responded to previous chemotherapy. The researchers want to see if combining two m...

Recruiting

Phase: NA Type: interventional Locations: Changzhou, , China

Clinical Study of Second-line Treatment in Advanced Colorectal Cancer with Chemotherapy with Bevacizumab or Cetuximab

NCT ID: NCT06540326

This clinical trial is studying a new treatment option for patients with advanced colorectal cancer that has not responded to previous therapies. The researchers want to see how effective and safe ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Hangzhou, Zhejiang, China

XNW27011 Study of Advanced Solid Tumor Subjects Who Failed Standard Therapies.

NCT ID: NCT06792435

This clinical trial is studying a new treatment called XNW27011 for patients with advanced cancers that have not responded to standard treatments. This includes types of cancer like pancreatic, lun...

Recruiting

Phase: PHASE1 Type: interventional Locations: 济南市, 山东省, China, 济南市, , China

Sequential Immunochemotherapy Treatment with Pembrolizumab Plus Dendritic Cell (DC) Vaccine Followed by Trifluridine/Tipiracil Plus Bevacizumab in Refractory Mismatch-repair-proficient (pMMR) or Microsatellite-stable (MSS) Metastatic Colorectal Cancer

NCT ID: NCT06522919

This clinical trial is exploring a new treatment approach for patients with metastatic colorectal cancer that is classified as microsatellite stable (MSS) or proficient in mismatch repair (pMMR), w...

Recruiting

Phase: PHASE2 Type: interventional Locations: Meldola, Forlì Cesena, Italy, Tricase, Lecce, Italy +1 more

Oral Chemotherapy, Targeted Therapy and Immunotherapy With/without Radiotherapy As 3rd- or Later-line Therapy for Advanced MSS/pMMR Colorectal Cancer

NCT ID: NCT06764680

This clinical trial is investigating new treatment options for patients with advanced colorectal cancer that has not responded to previous therapies. Specifically, the trial will look at the effect...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, Guangdong, China

Gut Microbiome Dynamics in Metastasized or Irresectable Colorectal Cancer

NCT ID: NCT03941080

This clinical trial is studying the gut microbiome, which is the collection of bacteria and other microorganisms living in our intestines, in patients with advanced colorectal cancer that cannot be...

Recruiting

Type: observational Locations: Groningen, , Netherlands, Groningen, , Netherlands +8 more

Molecular Characterisation of Colorectal Cancer Peritoneal Metastases

NCT ID: NCT05513716

This clinical trial is focused on understanding colorectal cancer that has spread to the lining of the abdomen, known as peritoneal metastases. Researchers want to learn more about the tumor cells ...

Recruiting

Type: observational Locations: Manchester, , United Kingdom

Safety and Efficacy of Fruquintinib Plus Chidamide and Sintilimab in the Third and Later Line Treatment of MSS/pMMR Metastatic Colorectal Cancer

NCT ID: NCT06685276

This clinical trial is exploring a new treatment approach for patients with metastatic colorectal cancer that cannot be surgically removed and has not responded to standard treatments. The study is...

Recruiting

Phase: PHASE2 Type: interventional Locations: Beijing, , China

A Real-world Study of Chidamide in Combination with PD-1/PD-L1 Antibodies and Anti-angiogenic Agents in Advanced MSS Colorectal Cancer

NCT ID: NCT06682247

This clinical trial is studying a new treatment approach for patients with advanced metastatic colorectal cancer (mCRC) that is microsatellite stable (MSS). The researchers want to see how well a c...

Not yet recruiting

Type: observational

SHR-1701 Combined with SHR2554 and BP102 for MCRC

NCT ID: NCT06679673

This clinical trial is exploring a new combination of treatments for patients with metastatic colorectal cancer (mCRC), which is a type of cancer that has spread beyond the colon or rectum. The stu...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Shanghai, Shanghai, China

PRELUDE-1 (Prospective Evaluation of Radiotherapy-induced Biologic Effects in Colorectal Cancer Oligometastatic Patients with LUng-limited Disease: Evolution of Cancer Genetics and Regulatory Immune Cells)

NCT ID: NCT04854213

The PRELUDE-1 trial is studying how a special type of radiation therapy, called stereotactic body radiation therapy (SBRT), affects the immune system and genetics in patients with colorectal cancer...

Recruiting

Phase: NA Type: interventional Locations: Napoli, , Italy

A Study of NILK-2301 in Patients with Locally Advanced or Metastatic Low Tumor Volume (LTV) Colorectal Cancer

NCT ID: NCT06663839

This clinical trial is studying a new treatment called NILK-2301 for patients with colorectal cancer that is locally advanced or has spread to other parts of the body, specifically for those with l...

Recruiting

Phase: PHASE1 Type: interventional Locations: Barcelona, , Spain, Madrid, , Spain

Technical Feasibility of Modified Early Post-Operative Intraperitoneal Chemotherapy (mEPIC)

NCT ID: NCT05913674

This clinical trial, called the mEPIC study, is looking at a new way to give chemotherapy after surgery for patients with certain types of cancer, specifically those with peritoneal carcinomatosis ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Montréal, Quebec, Canada

Cetuximab, Irinotecan, Toripalimab in RAS/BRAF Wild-type Ultraselected Right-sided Colorectal Cancer Study

NCT ID: NCT06547203

This clinical trial is studying a combination of three treatments—cetuximab, irinotecan, and a PD-1 inhibitor called toripalimab—specifically for patients with a type of colorectal cancer that has ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, Guangdong, China

Living Donor Liver Transplantation With Two Stage Hepatectomy for Patients With Isolated, Irresectable Colorectal Liver Metastases

NCT ID: NCT03488953

This clinical trial is exploring a new treatment approach for patients with colorectal cancer that has spread to the liver, known as liver metastases. The goal is to see if a combination of surgery...

Recruiting

Phase: NA Type: interventional Locations: Tübingen, , Germany, Jena, , Germany

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