Clinical Trials for Colorectal Cancer Metastatic

Find clinical trials for colorectal cancer metastatic. Discover research opportunities and treatment options in your area.

64 Active Trials Found

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Evaluation of the Efficacy of Two Guidance Techniques (Standard Injected CT vs Porto-scanner With Angio-CT) for Thermoablation Treatment of Colorectal Cancer Liver Metastases

NCT ID: NCT05665322

This clinical trial is studying two different methods to guide a treatment called thermoablation for patients with small liver tumors caused by colorectal cancer. Thermoablation uses heat to destro...

Recruiting

Phase: NA Type: interventional Locations: Nîmes, , France, Montpellier, , France

Galunisertib Combined With Capecitabine in Advanced CRC With PM

NCT ID: NCT05700656

This clinical trial is studying the combination of two medications, galunisertib and capecitabine, to see if they can help treat advanced colorectal cancer that has spread to the lining of the abdo...

Recruiting

Phase: PHASE1 Type: interventional Locations: Amsterdam, , Netherlands, Amsterdam, , Netherlands

Prospective National Cohort Evaluating Predictive Biomarkers of Resistance to Immunotherapy in Patients With MSI/dMMR Metastatic Colorectal Cancer (CORESIM)

NCT ID: NCT06353854

The CORESIM trial is studying how certain biological markers in patients with metastatic colorectal cancer can help predict whether they will benefit from a type of treatment called immunotherapy, ...

Recruiting

Type: observational Locations: Lille, , France, Orleans, , France +18 more

Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer

NCT ID: NCT06449989

The GENCONCOR-1 clinical trial is researching how similar the genetic characteristics are between the original colorectal cancer tumor and brain metastases, which are cancer cells that have spread ...

Recruiting

Type: observational Locations: Moscow, , Russian Federation

Efficacy and Safety of 90Y Microsphere Combined With FOLFIRI and Bevacizumab in Second-line Treatment of CRLM

NCT ID: NCT06447727

This clinical trial is exploring a new treatment approach for patients with colorectal cancer that has spread to the liver, known as colorectal cancer liver metastases (CRLM). The study is specific...

Recruiting

Type: observational Locations: Nanjing, Jiangsu, China

Exploration of Therapeutic Strategies for NeoRAS Wild-type Metastatic Colorectal Cancer Based on Circulating Tumor DNA

NCT ID: NCT06440902

This clinical trial is looking at a specific type of metastatic colorectal cancer, which means the cancer has spread beyond the colon and rectum. Researchers are studying how a change in the RAS ge...

Recruiting

Phase: PHASE2 Type: interventional Locations: Shanghai, Shanghai, China, Shanghai, Shanghai, China

Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases

NCT ID: NCT05248581

This clinical trial is studying the effects of living donor liver transplantation (LDLT) for patients with colorectal cancer that has spread to the liver, a condition known as metastatic colorectal...

Recruiting

Type: observational Locations: Rochester, New York, United States

Dynamics of MSI and Genomic Profile of Colorectal Cancer In the Course of Immune Checkpoint Inhibitor Therapy

NCT ID: NCT06414304

This clinical trial is looking at how certain genetic changes in colorectal cancer (CRC) can affect patients' responses to a type of treatment called immune checkpoint inhibitors (ICIs). Colorectal...

Recruiting

Type: observational Locations: Moscow, , Russian Federation, Moscow, , Russian Federation

Trifluridine/Tipiracil Combined With Cetuximab in the Treatment of Third-line and Above RAS/BRAF Wild-type mCRC

NCT ID: NCT06379399

This clinical trial is studying a new treatment for patients with advanced colorectal cancer that has spread to other parts of the body, specifically those whose cancer has not mutated in certain g...

Recruiting

Phase: PHASE1 Type: interventional Locations: Hangzhou, Zhejiang, China

Early Detection of Treatment Failure in Metastatic Colorectal Cancer Patients

NCT ID: NCT05068531

This clinical trial is looking at how to detect when treatment for metastatic colorectal cancer (mCRC-LR) is not working as well as hoped. Currently, patients with this type of cancer often receive...

Recruiting

Type: observational Locations: Montreal, Quebec, Canada

Chemoembolization (Lifepearls-Irinotecan) in Patients With Colorectal Cancer and Metastatic Disease

NCT ID: NCT04595266

The clinical trial titled "Chemoembolization (Lifepearls-Irinotecan) in Patients With Colorectal Cancer and Metastatic Disease" is studying a new treatment approach for patients with colorectal can...

Recruiting

Phase: PHASE2 Type: interventional Locations: Madrid, , Spain, Madrid, , Spain +10 more

Holmium-166 TARE in Liver Limited Unresectable Colorectal Cancer Patients

NCT ID: NCT06332079

This clinical trial is studying a new treatment approach for patients with colorectal cancer that has spread to the liver but cannot be surgically removed. The treatment being tested combines a typ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Pisa, , Italy, Pisa, , Italy

A Clinical Study of BioTTT001 in Combination With Toripalimab and Regorafenib in Patients With Colorectal Cancer

NCT ID: NCT06283134

This clinical trial is studying a new treatment called BioTTT001, which is being tested in combination with two other medications, Toripalimab and Regorafenib, for patients with metastatic colorect...

Not yet recruiting

Phase: PHASE1 Type: interventional

A Clinical Study of T3011 in Combination With Toripalimab and Regorafenib in Patients With Colorectal Cancer

NCT ID: NCT06283303

This clinical trial is studying a new treatment option for patients with metastatic colorectal cancer, which means the cancer has spread to the liver. The trial is looking at a combination of three...

Not yet recruiting

Phase: PHASE1 Type: interventional

Radioembolization in Elderly/ Fragile Patients With mCRC

NCT ID: NCT05092880

This clinical trial is studying a treatment called radioembolization (RE) for elderly or frail patients with metastatic colorectal cancer (mCRC), specifically when the cancer has spread to the live...

Recruiting

Phase: PHASE2 Type: interventional Locations: Utrecht, , Netherlands

Ablation vs Resection of Colorectal Cancer Liver Metastases

NCT ID: NCT05129787

This clinical trial is studying two different treatments for patients with colorectal cancer that has spread to the liver. It aims to find out whether surgical removal of the tumors (called resecti...

Recruiting

Phase: NA Type: interventional Locations: Oslo, , Norway

Evaluation of Tumour Growth and Oncological Treatment in Patients With CRLM Using Zebra Fish Embryo Model

NCT ID: NCT05289076

This clinical trial is studying how to improve cancer treatment for patients with colorectal cancer that has spread to the liver. Researchers are using zebrafish embryos as a model to see how tumor...

Recruiting

Phase: PHASE1 Type: interventional Locations: Linköping, Ostergotland, Sweden

Efficacy of Modified Fruquintinib in Colorectal Cancer Liver Metastases: A Phase II Study

NCT ID: NCT06018714

This clinical trial is studying a medication called modified fruquintinib to see if it can help patients with advanced colorectal cancer who have achieved a state known as "no evidence of disease" ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, Guangdong, China

Chemotherapy and Immunotherapy as Treatment for MSS Metastatic Colorectal Cancer With High Immune Infiltrate

NCT ID: NCT04262687

**Summary of the Clinical Trial on Chemotherapy and Immunotherapy for Metastatic Colorectal Cancer** This clinical trial is exploring whether a combination of chemotherapy and a type of immunother...

Recruiting

Phase: PHASE2 Type: interventional Locations: Beauvais, , France, Caluire Et Cuire, , France +86 more

Colorectal Pulmonary Metastases: Pulmonary Metastasectomy Versus Stereotactic Ablative Radiotherapy

NCT ID: NCT05808790

The COPPER trial is a clinical study designed to compare two different treatments for patients with up to three lung tumors caused by colorectal cancer. The two treatment options being studied are ...

Not yet recruiting

Phase: NA Type: interventional Locations: Amsterdam, , Netherlands

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