Clinical Trials for Crohn Disease

Exocrine Pancreatic Insufficiency's Prevalence in Active Crohn's Disease

NCT ID: NCT03915262

This clinical trial is studying how common a condition called exocrine pancreatic insufficiency (EPI) is in people who have active Crohn's disease. EPI happens when the pancreas does not produce en...

PRecisiOn Microbiome Directed ExtensiOn of Anti-TNFα Crohn's Disease ThErapy in Children: The PROMOTE Trial

NCT ID: NCT06301477

The PROMOTE Trial is a clinical study aimed at exploring whether a special type of resistant starch (a kind of dietary fiber) can help improve gut health in children with Crohn's Disease. This resi...

Use of Psychologist-administered Cognitive Behavioral Therapy (CBT) or Self-administered CBT for the Treatment of Anxiety and/or Depression in Inflammatory Bowel Disease (IBD)

NCT ID: NCT05377840

This clinical trial is looking at two different approaches to help people with Crohn's disease who also struggle with anxiety and depression. The study is comparing Cognitive Behavioral Therapy (CB...

Proactive Infliximab Optimization Using a Pharmacokinetic Dashboard Versus Standard of Care in Patients With Inflammatory Bowel Disease: The OPTIMIZE Trial

NCT ID: NCT04835506

KONO-S Anastomosis Compared to Conventional Ileocolonic Anastomosis to Reduce Recurrence in Crohn's Disease

NCT ID: NCT05974358

The KOALA study is a clinical trial that is investigating a new surgical technique called KONO-S anastomosis for patients with Crohn's disease. Crohn's disease is a long-lasting condition that caus...

Autologous Stem Cells in the Management of Fistulating Perianal Crohn's Disease

NCT ID: NCT06822686

This clinical trial is looking at a new way to treat a condition called fistulating perianal Crohn's disease, which affects some patients with Crohn's disease. Crohn's disease is a long-term condit...

Standardized Microbiota Transplant Therapy in Crohn's Disease

NCT ID: NCT06631586

This clinical trial is studying a new treatment for Crohn's disease, a condition that causes inflammation in the digestive tract. The researchers want to find out if two different types of encapsul...

Precise Infliximab Exposure and Pharmacodynamic Control

NCT ID: NCT05660746

This clinical trial is studying a new way to give treatment for Crohn's Disease, a condition that affects the digestive system. The researchers want to find out if using a special computer program ...

National GMA Post-market Clinical Follow-up Study (GRACE)

NCT ID: NCT05636709

The GRACE study is looking at a treatment called granulocytapheresis (GMA) for people with inflammatory bowel diseases, specifically Crohn's disease and ulcerative colitis. This treatment helps red...

Diagnostic Concordance of MR Enterography and Ultrasound for Treatment Response Assessment in Crohn's Disease (MANTRA)

NCT ID: NCT06800326

The MANTRA trial is studying how well two different imaging tests—MR Enterography (MRE) and Intestinal Ultrasound (IUS)—can assess the effectiveness of treatment for Crohn's disease. Crohn's diseas...

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

NCT ID: NCT05781152

The CAMEO study is a clinical trial aimed at understanding how well children with newly diagnosed Crohn's disease (CD) respond to a specific treatment called anti-TNF therapy, which helps reduce in...

Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project

NCT ID: NCT02103361

The OTIS Autoimmune Diseases in Pregnancy Study is looking at how two medications, Stelara and Tremfya, might affect pregnancies. This study aims to gather information about women who have taken th...

Quantitative Fluorescence Molecular Imaging of Ustekinumab-800CW to Elucidate the Drug Distribution Throughout Inflamed Tissue in Crohn's Disease and Psoriasis.

NCT ID: NCT05725876

This clinical trial is studying how a drug called ustekinumab works in people with Crohn's disease and psoriasis, which are long-term conditions that cause inflammation. Ustekinumab is a treatment ...

Bowel Preparation for Colonoscopy Among Individuals With Crohn's and Ulcerative Colitis Disease.

NCT ID: NCT06298461

This clinical trial is exploring the best way for people with Crohn's disease or ulcerative colitis to prepare their bowels before having a colonoscopy, which is a procedure that allows doctors to ...

Study on the Long-Term Risk of Recurrence of Anoperineal Fistula in Crohn's Disease

NCT ID: NCT06514092

This clinical trial is studying the long-term risk of recurring anal fistulas in patients with Crohn's disease who have received specific treatments. An anal fistula is an abnormal connection betwe...

De-escalation of Anti-TNF Therapy in Inflammatory Bowel Disease

NCT ID: NCT04646187

Study on the Treatment of Anal Fistulas Using Alofisel Versus Fat Autologous Stem Cells

NCT ID: NCT05974280

This clinical trial is exploring two different treatments for complex anal fistulas related to Crohn's disease. The first treatment being studied is called ALOFISEL®, a new cell therapy that uses s...

Evaluation of a Remote Monitoring Application in the Follow-up of Patients With Active Inflammatory Bowel Diseases

NCT ID: NCT06742385

The clinical trial titled "Evaluation of a Remote Monitoring Application in the Follow-up of Patients With Active Inflammatory Bowel Diseases" is looking at a new tool called MedicWise that helps m...

Individual Treatment of Ustekinumab in Perianal Fistulizing Crohn's Disease

NCT ID: NCT06739278

This clinical trial is looking at the effectiveness of a medication called ustekinumab for treating a specific condition known as perianal fistulizing Crohn's disease. Crohn's disease is an inflamm...

Analysis of Biologic Signatures in Crohn's Patients Undergoing Surgery

NCT ID: NCT06146335