Clinical Trials for Efficacy

Find clinical trials for efficacy. Discover research opportunities and treatment options in your area.

27 Active Trials Found

Showing 27 trials on this page

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Bilateral Peribulbar Block for Cataract Surgery

NCT ID: NCT07000669

This clinical trial is focused on studying a procedure called bilateral peribulbar block, which is a type of anesthesia used during cataract surgery. The goal of the study is to find out if this me...

Recruiting

Type: observational Locations: Tanta, El Gharbia, Egypt

Efficacy of iPSC-Derived Motor Neuron Cells (XS228) in Subacute Spinal Cord Injury: A Phase II Randomized Controlled Trial

NCT ID: NCT06974968

This clinical trial is looking at a new treatment called XS228, which is a special type of cell therapy made from lab-created stem cells. The goal is to see if XS228 can help repair damaged nerves ...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, Guangdong, China

Safety and Early Efficacy of iPSC-Derived Motor Neuron Cells (XS228) in Subacute Spinal Cord Injury: A Phase I Trial

NCT ID: NCT06976229

This clinical trial, called the Phase I Trial of iPSC-Derived Motor Neuron Cells (XS228), is designed to explore the safety and initial effectiveness of a new treatment for people with spinal cord ...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Guangzhou, Guangdong, China

Phase 1/2 Study of HYP-2090PTSA in Patients With Advanced Solid Tumors Harboring KRAS Mutation

NCT ID: NCT06243354

This clinical trial is studying a new treatment called HYP-2090PTSA for patients who have advanced solid tumors with a specific genetic change known as a KRAS mutation. The trial has two parts: the...

Recruiting

Phase: PHASE1 Type: interventional Locations: Shenyang, Liaoning, China, Shanghai, Shanghai, China +5 more

A Phase I Study on Autologous Tumor Infiltrating Lymphocytes Injection (GC101 TIL) for the Treatment of Advanced Malignant Solid Tumors

NCT ID: NCT05417750

This clinical trial is studying a new treatment called GC101, which involves using a patient's own immune cells (specifically tumor-infiltrating lymphocytes) to fight advanced solid tumors like mel...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, Beijing, China

Effect of Vitamin D Supplementation on the Efficacy and Adverse Effects of Neoadjuvant Therapy in Patients with Breast Cancer

NCT ID: NCT06642428

This clinical trial is studying whether taking vitamin D supplements can help improve the effectiveness and reduce the side effects of neoadjuvant therapy for patients with breast cancer. Neoadjuva...

Recruiting

Phase: NA Type: interventional Locations: Xining, Qinghai, China

Phase 1/2 Clinical Study of HY07121 Powder for Solution for Infusion in Patients With Advanced Solid Tumors

NCT ID: NCT06639256

This clinical trial is investigating a new treatment called HY07121 for patients with advanced solid tumors, which are cancers that can't be removed through surgery. The main goals of the study are...

Recruiting

Phase: PHASE1 Type: interventional Locations: Jinan, , China

A Phase Ⅰb Study on Autologous GC101 TIL Injection for the Treatment of Advanced Melanoma (MIZAR-002)

NCT ID: NCT06120712

This clinical trial, called the MIZAR-002 study, is exploring a new treatment for advanced melanoma, which is a serious type of skin cancer. The treatment focuses on using a person’s own immune cel...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, , China, Beijing, Beijing, China

AK112 Plus Platinum-based Chemotherapy for EGFR/ALK/ROS1 Positve NSCLC

NCT ID: NCT06196814

This clinical trial is investigating a new treatment approach for patients with a type of lung cancer called non-small cell lung cancer (NSCLC) who have specific genetic markers (EGFR, ALK, or ROS1...

Not yet recruiting

Phase: PHASE1 Type: interventional

Fluzoparib in Combination With Apatinib Mesylate for Maintenance Therapy in Stage III-IV Ovarian Cancer

NCT ID: NCT06539091

This clinical trial is exploring the use of two medications, fluzoparib and apatinib mesylate, to see how effective and safe they are for women with advanced ovarian cancer. The main goal of the st...

Not yet recruiting

Phase: PHASE3 Type: interventional

Effect of PPV+ILM Peeling +/- Subretinal Injection of Ringer Lactate in Management of Nontractional Refractory DME

NCT ID: NCT06271473

This clinical trial is looking at a new treatment approach for patients with a condition called diabetic macular edema (DME) that is not responding well to standard therapies. The study will evalua...

Recruiting

Phase: NA Type: interventional Locations: Cairo, , Egypt

Efficacy and Safety of AK104 (PD-1/CTLA-4 Bispecial Antibody) Combined With Chemotherapy for Neoadjuvant Treatment of Advanced Ovarian Cancer

NCT ID: NCT06542549

This clinical trial is studying a new treatment for advanced ovarian cancer, specifically looking at a medication called AK104, which is combined with chemotherapy. The goal is to find out if this ...

Not yet recruiting

Phase: PHASE3 Type: interventional

Clinical Follow-up Study of Rituximab in the Treatment of Nephrotic Syndrome in Children

NCT ID: NCT06530004

This clinical trial is studying the effectiveness and safety of a medication called rituximab (RTX) for treating nephrotic syndrome in children. Nephrotic syndrome is a condition that causes the bo...

Recruiting

Type: observational Locations: Xiamen, Fujian, China

Safety and Efficacy of Distal Radial Approach (SAFE-BOX)

NCT ID: NCT05776550

The SAFE-BOX trial is a study looking at a new way to perform heart procedures called the distal radial approach. This method involves accessing the heart through the wrist, which may be safer and ...

Recruiting

Type: observational Locations: Yongin, Gyeonggi Do, Korea, Republic Of

Is Local Injection of Mesenchymal Stem Cells After Endoscopic Dilation Safe and Does it Improve the Outcome of Intestinal Stricture in Patients With Crohn's Disease?

NCT ID: NCT06317818

This clinical trial is exploring whether injecting a special type of cell, called mesenchymal stem cells (MSCs), directly into the intestine can help improve blockages (strictures) in patients with...

Recruiting

Phase: PHASE2 Type: interventional Locations: Liège, , Belgium

Tirelizumab Combined With Chemotherapy in the Treatment of HER-2 Negative Locally Advanced Gastric Cancer

NCT ID: NCT06284746

This clinical trial is studying a new treatment approach for patients with locally advanced gastric cancer that is HER-2 negative. Researchers want to find out if combining a drug called tirelizuma...

Recruiting

Phase: PHASE2 Type: interventional Locations: Beijing, Beijing, China

Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell Carcinoma

NCT ID: NCT06281886

This clinical trial is exploring a treatment approach for patients with a type of esophageal cancer called esophageal squamous cell carcinoma, which is locally advanced and cannot be surgically rem...

Recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, Guangdong, China

Genome-Based Assessment of Niraparib (ZEJULA®) Efficacy in Advanced Solid TumorS With Homologous Recombination Deficiency

NCT ID: NCT06237205

This clinical trial is studying the effectiveness of a medication called Niraparib (ZEJULA®) in patients with advanced solid tumors that have specific genetic mutations affecting DNA repair, known ...

Not yet recruiting

Phase: PHASE2 Type: interventional

Efficacy and Safety Prediction of Milrinone or Levosimendan as Initial Inotropic Drug Therapy in Patients With Acute and Advanced Heart Failure With Renal Insufficiency

NCT ID: NCT06205758

This clinical trial is studying two medications, levosimendan and milrinone, to see how effective and safe they are for treating patients with acute heart failure, especially those who may also hav...

Recruiting

Type: observational Locations: Jinan, Shandong, China

Treatment of MB07133 Plus Sintilimab in Patients With Hepatocellular Carcinoma

NCT ID: NCT06141109

This clinical trial is studying a new treatment for patients with hepatocellular carcinoma, a type of primary liver cancer. The researchers want to see how safe and effective a combination of two m...

Recruiting

Phase: PHASE1 Type: interventional Locations: Jilin, Changchun, China

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