Clinical Trials for EGFR Gene Mutation

Find clinical trials for egfr gene mutation. Discover research opportunities and treatment options in your area.

23 Active Trials Found

Showing 23 trials on this page

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Nitroglycerin Plus Radiotherapy Versus Conventional Radiotherapy in Patients With Lung Cancer.

NCT ID: NCT06238882

This clinical trial is investigating whether adding transdermal nitroglycerin (NTG) to standard cranial radiation therapy can improve treatment outcomes for patients with stage IV non-small cell lu...

Recruiting

Phase: NA Type: interventional Locations: Mexico City, , Mexico

EQUAL: EGFR ctDNA QUantative Assessment for Lung Cancer Screening in Asian and Latinx Populations

NCT ID: NCT06716580

The EQUAL trial is looking at a new blood test called the Circulating free DNA (cfDNA) Assay to help screen for a type of lung cancer known as EGFR-positive lung cancer. This study is specifically ...

Recruiting

Phase: NA Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States +5 more

Whole Body HER3 Quantification With Radiolabelled Patritumab Deruxtecan (HER3-DXd) PET/CT

NCT ID: NCT06222489

This clinical trial is studying a new treatment called patritumab deruxtecan (HER3-DXd) for patients with advanced non-small cell lung cancer (NSCLC) that has certain genetic mutations. The goal is...

Recruiting

Phase: PHASE2 Type: interventional Locations: Amsterdam, North Holland, Netherlands

Evaluating High-dose Furmonertinib with Bevacizumab and Pemetrexed for EGFRm NSCLC with Leptomeningeal Metastasis

NCT ID: NCT06643000

This clinical trial is studying a new treatment approach for patients with non-small cell lung cancer (NSCLC) that has spread to the membranes surrounding the brain and spine, known as leptomeninge...

Recruiting

Phase: NA Type: interventional Locations: Zhengzhou, Henan, China, Zhengzhou, Henan, China

Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells

NCT ID: NCT06186401

This clinical trial is studying a new treatment called E-SYNC CAR T-cell therapy for patients with a specific type of brain cancer known as glioblastoma that has a certain genetic mutation (EGFRvII...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Francisco, California, United States

Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy

NCT ID: NCT03042221

This clinical trial is looking at how cancer cells in patients with advanced lung cancer respond to specific targeted treatments, called Tyrosine Kinase Inhibitors (TKIs). The goal is to identify e...

Recruiting

Type: observational Locations: Aurora, Colorado, United States

Nintedanib Plus EGFR TKI In EGFR-mutated Non-small Cell Lung Cancer Patients

NCT ID: NCT06071013

This clinical trial is studying the combination of two treatments, Nintedanib and EGFR-TKI, for patients with advanced non-small cell lung cancer (NSCLC) that has become resistant to previous treat...

Recruiting

Phase: PHASE1 Type: interventional Locations: Taichung, , Taiwan

Exploring the Mechanism of Primary Resistance to Third-generation EGFR-TKIs as First-line Treatment in EGFR-positive Advanced NSCLC (PRECISE Study)

NCT ID: NCT05598528

The PRECISE Study is a clinical trial aimed at understanding why some patients with advanced non-small cell lung cancer (NSCLC) do not respond to a specific type of medication called third-generati...

Recruiting

Type: observational Locations: Changsha, Hunan, China

Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation

NCT ID: NCT04322890

This clinical trial is studying different treatment strategies for patients with advanced non-small cell lung cancer (NSCLC) who have specific genetic changes, known as oncogenic mutations, includi...

Recruiting

Phase: PHASE2 Type: interventional Locations: Changsha, Hunan, China

Feasibility of Intratumoral Washing Fluid for Detecting EGFR Mutations in Lung Cancer

NCT ID: NCT05517083

This clinical trial is looking at a new way to detect specific mutations in the EGFR gene in patients with non-small cell lung cancer (NSCLC). The researchers want to see if using a washing fluid f...

Recruiting

Phase: NA Type: interventional Locations: Busan, , Korea, Republic Of

Alisertib in Combination With Osimertinib in Metastatic EGFR-mutant Lung Cancer

NCT ID: NCT04085315

This clinical trial is exploring the safety and effectiveness of two medications, alisertib and osimertinib, used together to treat patients with advanced lung cancer that has a specific gene mutat...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Francisco, California, United States

Osimertinib and Etoposide as First-Line Treatment in Osimertinib-Resistant Advanced EGFR-Mutant NSCLC

NCT ID: NCT06436144

This clinical trial is looking at a new treatment approach for patients with advanced non-small cell lung cancer (NSCLC) that has a specific genetic mutation called EGFR. While the standard treatme...

Not yet recruiting

Phase: PHASE2 Type: interventional

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

NCT ID: NCT03175224

The APL-101 clinical trial is exploring a new treatment for patients with advanced lung cancer, specifically those with certain genetic changes called c-Met Exon 14 skipping mutations or MET amplif...

Recruiting

Phase: PHASE2 Type: interventional Locations: Rochester, Minnesota, United States, Madison, Wisconsin, United States +113 more

Neoadjuvant Almonertinib Followed by Chemo-immunotherapy in II-IIIB EGFR-mutant NSCLC

NCT ID: NCT06300424

This clinical trial is studying a new treatment approach for patients with non-small cell lung cancer (NSCLC) who have a specific genetic change called an EGFR mutation. The trial will involve givi...

Recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, Guangdong, China

Adjuvant Target Therapy Guided by ctDNA-MRD in Patients With EGFR-mutant II-IIIA Non-small Cell Lung Cancer (ECTOP-1022)

NCT ID: NCT06323148

The ECTOP-1022 clinical trial is studying the best ways to treat patients with a specific type of lung cancer called non-small cell lung cancer (NSCLC) that has a mutation in the EGFR gene. This tr...

Not yet recruiting

Phase: PHASE3 Type: interventional

Applying Mobile Healthcare Education to Improve Cutaneous Self-care Capability

NCT ID: NCT06291688

This clinical trial is studying how different ways of providing mobile healthcare education can help cancer patients take better care of their skin while receiving a specific cancer treatment. Pati...

Recruiting

Phase: NA Type: interventional Locations: Taipei, , Taiwan

Erlotinib Combined With Chemotherapy in TKI Resistant Non-Small Cell Lung Cancers

NCT ID: NCT02098954

This clinical trial is studying the use of a medication called erlotinib combined with chemotherapy for patients with advanced non-small cell lung cancer (NSCLC) who have developed resistance to fi...

Recruiting

Phase: PHASE2 Type: interventional Locations: Changsha, Hunan, China

The Efficacy of Double-dose Furmonertinib in the Treatment of Patients With Slow Osimertinib-resistant NSCLC

NCT ID: NCT06117644

This clinical trial is exploring the effectiveness of a double dose of Furmonertinib, a medication designed to treat non-small cell lung cancer (NSCLC) in patients who have developed resistance to ...

Not yet recruiting

Type: observational

Efficacy and Safety of Neoantigen Peptide Vaccine in the Treatment of Advanced NSCLC Progressed After EGFR-TKI Treatment

NCT ID: NCT06095934

This clinical trial is studying a new treatment approach for patients with advanced non-small cell lung cancer (NSCLC) who have not responded to previous therapies. Specifically, it combines a neoa...

Recruiting

Phase: NA Type: interventional Locations: Nanjing, , China

Osimertinib Combined With Aspirin Neoadjuvant Therapy for Resectable EGFR Mutated NSCLC Patients.

NCT ID: NCT06018688

This clinical trial is studying the combination of two medications, Osimertinib and Aspirin, as a treatment before surgery for patients with a specific type of lung cancer called non-small cell lun...

Not yet recruiting

Phase: PHASE2 Type: interventional

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