Clinical Trials for Esophageal Cancer

Find clinical trials for esophageal cancer. Discover research opportunities and treatment options in your area.

237 Active Trials Found

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Nutrition Intervention Trials in Linxian Follow-up Study

NCT ID: NCT00342654

This is a long‑term follow‑up study of about 34,000 adults who took part in two large nutrition trials in Linxian, China (1985–1991) that looked at vitamins and minerals to help prevent esophageal ...

Enrolling by invitation

Type: observational Locations: Beijing, China

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

NCT ID: NCT05891171

This clinical trial is studying a new treatment called AB598 for patients with advanced cancers, including types like bladder, cervical, lung, and breast cancer, among others. The main goal is to s...

Recruiting

Phase: PHASE1 Type: interventional Locations: Rochester, Minnesota, United States, New Orleans, Louisiana, United States +25 more

Endostatin Adenovirus With Checkpoint Inhibitor in Advanced Head and Neck or Esophageal Cancer

NCT ID: NCT07154108

This clinical trial is studying a new treatment approach for people with advanced head and neck cancer or a type of esophageal cancer called esophageal squamous cell carcinoma. The treatment involv...

Not yet recruiting

Phase: PHASE1 Type: interventional

Brachytherapy With Radiotherapy and Immunotherapy: Guided HDR Trial in Esophageal Squamous Cell Carcinoma

NCT ID: NCT07152678

This clinical trial is studying a new way to treat a type of esophageal cancer called esophageal squamous cell carcinoma. The researchers want to see if adding a treatment called high-dose-rate (HD...

Recruiting

Phase: PHASE2 Type: interventional

High-flow Nasal Cannula Oxygenation in Sedated Endoscopy for High-risk Obstructive Sleep Apnea Patients

NCT ID: NCT07155330

This clinical trial is studying whether using a special type of oxygen delivery called High-Flow Nasal Cannula (HFNC) can help prevent low oxygen levels (hypoxia) in patients with a high risk of sl...

Not yet recruiting

Phase: NA Type: interventional

Substudy 06C: A Study of Sacituzumab Tirumotecan (MK-2870) With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

NCT ID: NCT06469944

This clinical trial is exploring how safe and effective a combination of three treatments—sacituzumab tirumotecan, pembrolizumab, and a type of chemotherapy—can be for patients with certain types o...

Recruiting

Phase: PHASE1 Type: interventional Locations: Brest, Bretagne, France, Fuzhou, Fujian, China +48 more

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

NCT ID: NCT06465069

This clinical trial is studying a new drug called LY4052031 to see if it is safe and effective for patients with advanced or metastatic solid tumors, including types of bladder, breast, lung, and p...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, New York, New York, United States +36 more

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT05581004

This clinical trial is testing a new treatment called RO7502175, both on its own and in combination with another medication called atezolizumab. The study is designed for adults who have locally ad...

Recruiting

Phase: PHASE1 Type: interventional Locations: Detroit, Michigan, United States, Atlanta, Georgia, United States +46 more

DESTINY-PANTUMOUR04

NCT ID: NCT07124000

This clinical trial, called DESTINY-PANTUMOUR04, is studying a medicine called T-DXd to see how well it works in people with certain advanced cancers that have a specific marker called HER2-positiv...

Not yet recruiting

Type: observational

Pan-tumor MRD Study

NCT ID: NCT06605404

The Pan-tumor MRD Study is a clinical trial aimed at improving our understanding of certain types of cancer, including muscle invasive bladder cancer, esophageal cancer, gastric cancer, melanoma, n...

Recruiting

Type: observational Locations: San Diego, California, United States, Maumee, Ohio, United States

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT06172478

This clinical trial is studying a new treatment called HER3-DXd for patients with advanced solid tumors, which are cancers that have spread and cannot be treated with surgery or radiation. The tria...

Recruiting

Phase: PHASE2 Type: interventional Locations: Baltimore, Maryland, United States, Madrid, Spain +81 more

Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™)

NCT ID: NCT07124351

This clinical trial is studying a new way to help doctors see certain types of gastrointestinal cancers—like stomach, esophagus, and appendix cancers—more clearly during surgery. The study uses a s...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Los Angeles, California, United States

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

NCT ID: NCT06695845

This clinical trial is studying a new treatment called zanidatamab for patients with certain types of solid tumors that have high levels of a protein called HER2. These tumors include breast, gastr...

Recruiting

Phase: PHASE2 Type: interventional Locations: Detroit, Michigan, United States, Houston, Texas, United States +20 more

Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation

NCT ID: NCT06181656

This clinical trial is looking at how well patients with esophageal cancer respond to the pneumococcal vaccine after receiving radiation treatment. Specifically, it aims to understand how different...

Recruiting

Type: observational Locations: Houston, Texas, United States

64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer

NCT ID: NCT06298916

This clinical trial is exploring a new imaging agent called 64Cu-LNTH-1363S, which is designed to help doctors see certain types of cancer better during scans. Specifically, the study is looking at...

Recruiting

Phase: PHASE1 Type: interventional Locations: Cincinnati, Ohio, United States, Duarte, California, United States +3 more

Magnetic Sentinel Lymph Node Mapping in Upper Gastro-Intestinal Cancer: A Feasibility Clinical Investigation

NCT ID: NCT05899985

This clinical trial is exploring a new method called the FerroTrace® system for identifying sentinel lymph nodes (SLNs) in patients with gastric and esophageal cancers. These nodes are the first pl...

Recruiting

Phase: NA Type: interventional Locations: Adelaide, South Australia, Australia, Heidelberg, Victoria, Australia +2 more

A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

NCT ID: NCT06123338

This clinical trial is studying a new treatment approach for patients with certain types of esophagogastric cancer, specifically those with a HER2 gene mutation. Researchers want to see if combinin...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Houston, Texas, United States +10 more

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

NCT ID: NCT05983432

This clinical trial is studying a new treatment called BL-B01D1 for patients with metastatic or unresectable non-small cell lung cancer (NSCLC) and other solid tumors, such as certain types of brea...

Recruiting

Phase: PHASE1 Type: interventional Locations: Orange, California, United States, Boston, Massachusetts, United States +43 more

Impact of CES1 Genotype on Capecitabine Exposure in Cancer Patients

NCT ID: NCT07114627

This clinical trial is studying how a person's genetic makeup affects the way their body handles a cancer drug called capecitabine, which is commonly used to treat cancers of the stomach, esophagus...

Recruiting

Type: observational Locations: Rotterdam, Netherlands

Development and Validation of a Risk Prediction Model for Gastric Retention in Patients Undergoing Sedated Gastroscopy

NCT ID: NCT07104214

This clinical trial is studying how to predict when food or liquid stays in the stomach longer than it should before a sedated gastroscopy, which is a procedure where a doctor looks inside the uppe...

Not yet recruiting

Type: observational Locations: Hangzhou, Zhejiang, China, Hangzhou, Zhejiang, China +1 more

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