Clinical Trials for Esophageal Cancer

Nutrition Intervention Trials in Linxian Follow-up Study

NCT ID: NCT00342654

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT05581004

This clinical trial is testing a new treatment called RO7502175, both on its own and in combination with another medication called atezolizumab. The study is designed for adults who have locally ad...

Selective TrkA Inhibitor VMD-928 to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

NCT ID: NCT03556228

This clinical trial is studying a new medication called VMD-928, which is being tested for patients with certain types of advanced cancers and lymphomas that have not responded to standard treatmen...

A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

NCT ID: NCT06238479

This clinical trial is investigating a new drug called LY4101174 to see if it is safe and effective for people with advanced solid tumors that have come back or spread to other parts of the body. T...

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

NCT ID: NCT06239194

This clinical trial is testing a new treatment called MDX2001 for patients with advanced solid tumors, which are cancers that form in organs or tissues, such as breast, lung, or colorectal cancer. ...

APG-2449 in Patients With Advanced Solid Tumors

NCT ID: NCT03917043

This clinical trial is studying a new drug called APG-2449, which is designed to treat patients with advanced solid tumors, including specific types of lung cancer, esophageal cancer, ovarian cance...

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT06172478

This clinical trial is studying a new treatment called HER3-DXd for patients with advanced solid tumors, which are cancers that have spread and cannot be treated with surgery or radiation. The tria...

Substudy 06C: A Study of Sacituzumab Tirumotecan (MK-2870) With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

NCT ID: NCT06469944

This clinical trial is exploring how safe and effective a combination of three treatments—sacituzumab tirumotecan, pembrolizumab, and a type of chemotherapy—can be for patients with certain types o...

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

NCT ID: NCT06445972

This clinical trial is exploring new treatment options for patients with advanced esophageal or stomach cancer who have not responded to their first treatment. Specifically, the study is comparing ...

Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), in Subjects With Tumors With Oncogene Amplifications

NCT ID: NCT05827614

This clinical trial is studying a new treatment called BBI-355, which is designed for patients with certain types of advanced cancers, such as non-small cell lung cancer, breast cancer, and bladder...

Developing an Ecological and Tailored Nutritional Intervention to Improve Quality of Life in Esophageal Cancer Survivors

NCT ID: NCT07024849

This clinical trial is testing a special nutrition program designed to help people who have had surgery for esophageal cancer feel better and improve their quality of life. The program lasts four w...

PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy Plus Surgery for Locally Advanced ESCC (NEOCRTEC2101)

NCT ID: NCT05357846

The clinical trial called NEOCRTEC2101 is studying a new treatment approach for patients with locally advanced squamous cell esophageal cancer. Specifically, it aims to compare a combination of a P...

Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE）

NCT ID: NCT07004634

This clinical trial is looking at different ways to manage drainage after a specific type of surgery for esophageal cancer called minimally invasive esophagectomy. The researchers want to compare t...

Integrated Cancer Repository for Cancer Research

NCT ID: NCT02012699

The Integrated Cancer Repository for Cancer Research (iCaRe2) is a study designed to gather important information and samples from adults who have been diagnosed with cancer, those at high risk for...

A Study of PRT3789 in Combination With Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

NCT ID: NCT06682806

This clinical trial is looking at a new treatment combination of PRT3789 and pembrolizumab for patients with advanced solid tumors that have a specific genetic change called a SMARCA4 mutation. The...

Sentinel Lymph Node Mapping in Esophageal Cancer Using ICG Dye and NIR Imaging

NCT ID: NCT04400292

This clinical trial is studying a new method called sentinel lymph node mapping using a special dye (ICG) and imaging technology (NIR) to help doctors find out if esophageal cancer has spread to ne...

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

NCT ID: NCT05891171

This clinical trial is studying a new treatment called AB598 for patients with advanced cancers, including types like bladder, cervical, lung, and breast cancer, among others. The main goal is to s...

Intra-tumoral (IT) Injection of vvDD-hIL2-2-RG-1 for Metastatic Gastrointestinal and Peritoneal Tumors

NCT ID: NCT07001592

This clinical trial is studying a new experimental treatment called vvDD-hIL2, which is being tested for patients with advanced abdominal cancers, such as gastric and liver cancer. The goal of the ...

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

NCT ID: NCT06293898

This clinical trial is studying a new treatment called BL-M07D1 for patients with certain types of advanced cancers that have a protein called HER2. The goal is to find out if this treatment is saf...

NIF-Guided RAMIE Using ICG Versus OTE Feasibility RCT

NCT ID: NCT04938973

This clinical trial is studying a new surgical method for treating esophageal cancer called Robotic Assisted Minimally Invasive Esophagectomy (RAMIE). This technique uses advanced robotic technolog...