Clinical Trials for Esophageal Cancer

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

NCT ID: NCT06943521

This clinical trial is studying a new medication called MT-4561 to see how safe and effective it is for patients with various advanced solid tumors, such as head and neck cancer, lung cancer, breas...

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT05581004

This clinical trial is testing a new treatment called RO7502175, both on its own and in combination with another medication called atezolizumab. The study is designed for adults who have locally ad...

POP-UP: a Single-arm, Two-cohort Study: Trimodal Prehab for Upper GI and Pancreatic Cancer

NCT ID: NCT06275737

The POP-UP clinical trial is exploring a new approach to help patients with localized pancreatic cancer or esophageal cancer prepare for surgery and chemotherapy. This study is testing an 8-week pr...

A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

NCT ID: NCT06238479

This clinical trial is investigating a new drug called LY4101174 to see if it is safe and effective for people with advanced solid tumors that have come back or spread to other parts of the body. T...

Single Dose Investigator Initiated Pilot Study to Investigate CYTALUX (Pafolacianine) for Intraoperative Detection of Malignant Tissue in Subjects Undergoing Surgical Resection for Cancer.

NCT ID: NCT07039526

This clinical trial is studying a special drug called CYTALUX™ (pafolacianine) that helps surgeons see cancer during an operation. The drug attaches to cancer cells and makes them light up when vie...

The Intensive Nutritional Support in Esophageal Cancer Undergoing Neoadjuvant Therapy

NCT ID: NCT07067359

This clinical trial is studying how different types of nutritional support might help people with esophageal cancer who are receiving treatment before surgery (called neoadjuvant therapy). The goal...

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

NCT ID: NCT06695845

This clinical trial is studying a new treatment called zanidatamab for patients with certain types of solid tumors that have high levels of a protein called HER2. These tumors include breast, gastr...

Substudy 06C: A Study of Sacituzumab Tirumotecan (MK-2870) With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

NCT ID: NCT06469944

This clinical trial is exploring how safe and effective a combination of three treatments—sacituzumab tirumotecan, pembrolizumab, and a type of chemotherapy—can be for patients with certain types o...

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

NCT ID: NCT06445972

This clinical trial is exploring new treatment options for patients with advanced esophageal or stomach cancer who have not responded to their first treatment. Specifically, the study is comparing ...

Predicting Early Tumor Recurrence in Patients With Esophageal Squamous Cell Carcinoma

NCT ID: NCT06476067

This clinical trial is focused on improving the understanding of early tumor recurrence in patients with esophageal squamous cell carcinoma (ESCC), a type of cancer that affects the esophagus. Rese...

Oncolytic Virus in Esophageal Squamous Cell Carcinoma

NCT ID: NCT07061704

This clinical trial is testing a new treatment for a type of esophageal cancer called esophageal squamous cell carcinoma that cannot be removed by surgery at the time of diagnosis. The study combin...

A Trial of Palliative Chemotherapy, Radiation and Immune Treatment for Oesophageal Cancer: PALEO Study

NCT ID: NCT06290505

The PALEO Study is a clinical trial looking at new treatment options for people with esophageal cancer that is either locally advanced or has spread to other parts of the body. This trial aims to f...

Impact of Prehabilitation in Oncology Via Exercise- Esophageal (IMPROVE-Esophageal)

NCT ID: NCT06872515

The IMPROVE-Esophageal trial is studying how an exercise program before surgery can help adults with esophageal cancer feel better both physically and mentally. This program, called prehabilitation...

Non-gastric Conduit Reconstruction After Esophagectomy

NCT ID: NCT07064655

This clinical trial is studying a new way to rebuild the esophagus after surgery to remove cancer. Usually, doctors use the stomach to create a new pathway for food, but this study focuses on using...

A Multi Tumor, Open Phase I Clinical Study on the Progression of First-line Anti-tumor Therapy Using Cardonizumab Combined With Pulsed Low-dose Rate External Irradiation (PLDR)

NCT ID: NCT06232083

This clinical trial is exploring a new treatment approach for women with recurrent cervical cancer, specifically looking at how combining pulse low-dose rate radiotherapy (PLDR) with immune checkpo...

A Beta-only IL-2 ImmunoTherapY Study

NCT ID: NCT05086692

This clinical trial, called the Beta-only IL-2 ImmunoTherapY Study, is looking to test a new treatment called MDNA11 for patients with advanced solid tumors, which are types of cancer that have spr...

Nutrition Intervention Trials in Linxian Follow-up Study

NCT ID: NCT00342654

Patient Derived Organoids (PDOs) to Observe the Clinical Consistency of Personalized Neoadjuvant Therapy for Resectable Esophageal Squamous Cell Carcinoma

NCT ID: NCT07054086

This clinical trial is studying a new way to personalize treatment for people with esophageal squamous cell carcinoma, a type of esophageal cancer that can be surgically removed. Researchers are us...

Spanish Registry of Esophagogastric Cancer

NCT ID: NCT04958720

The Spanish Registry of Esophagogastric Cancer is a clinical trial designed to create a comprehensive online database that collects important information about patients with esophageal and stomach ...

Oesophagectomy and Chest Wall and Respiratory Function

NCT ID: NCT03835273

This clinical trial is studying how surgery for esophageal cancer affects breathing and chest movement. When patients have open surgery for this type of cancer, they often experience breathing prob...