Clinical Trials for Ewing Sarcoma

Find clinical trials for ewing sarcoma. Discover research opportunities and treatment options in your area.

34 Active Trials Found

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Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

NCT ID: NCT06395103

This clinical trial, called Substudy 01A, is investigating a new treatment called zilovertamab vedotin for children and young adults with certain types of blood cancers and solid tumors. Specifical...

Recruiting

Phase: PHASE1 Type: interventional Locations: Münster, Nordrhein Westfalen, Germany, São José Do Rio Preto, Sao Paulo, Brazil +60 more

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

NCT ID: NCT03618381

This clinical trial is looking at a new type of treatment called EGFR806 CAR T Cell Immunotherapy for children and young adults with certain types of solid tumors that have returned or didn’t respo...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States

Cabozantinib With Ifosfamide in Ewing's Sarcoma and Osteosarcoma

NCT ID: NCT06156410

This clinical trial is studying the combination of two drugs, cabozantinib and ifosfamide, to see how safe and effective they are for treating children and adults with Ewing sarcoma and osteosarcom...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Philadelphia, Pennsylvania, United States +3 more

Phase II Study of Irinotecan Liposome (II) Combined With Temozolomide and Fluzoparib in Recurrent or Metastatic Ewing Sarcoma

NCT ID: NCT06827717

This clinical trial is studying a combination of three medications—Irinotecan Liposome, Temozolomide, and Fluzoparib—as a treatment for patients with recurrent or metastatic Ewing sarcoma, a type o...

Recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, Guangdong, China

A Study of LY2880070 and Gemcitabine in People With Ewing Sarcoma,Ewing-Like Sarcoma, and Desmoplastic Small Round Cell Tumor

NCT ID: NCT05275426

This clinical trial is studying a new treatment combination for patients with Ewing sarcoma, Ewing-like sarcoma, or desmoplastic small round cell tumor. The treatment being tested combines a medica...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States

Early Ageing During Therapy in AYA Cancer Patients

NCT ID: NCT05062707

This clinical trial, titled "Early Ageing During Therapy in AYA Cancer Patients," is studying how cancer treatments affect young adults aged 18 to 39. The researchers want to understand if these tr...

Recruiting

Type: observational Locations: Groningen, , Netherlands, Groningen, , Netherlands

Difluoromethylornithine (DFMO) and AMXT-1501 for Neuroblastoma, CNS Tumors, and Sarcomas

NCT ID: NCT06465199

This clinical trial is exploring a new treatment for children and young adults with certain types of cancer, including neuroblastoma, brain tumors like DIPG, and specific sarcomas. The study is tes...

Not yet recruiting

Phase: PHASE1 Type: interventional

Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult Participants

NCT ID: NCT06566092

This clinical trial is exploring a new treatment using autologous tumor-infiltrating lymphocytes (TILs) for children, teenagers, and young adults who have solid tumors like soft tissue sarcoma, mel...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Saint Petersburg, Florida, United States +1 more

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

NCT ID: NCT04897321

The 3CAR trial is a research study looking at a new type of treatment called immunotherapy for children and young adults (up to 21 years old) with specific types of solid tumors, such as neuroblast...

Recruiting

Phase: PHASE1 Type: interventional Locations: Memphis, Tennessee, United States

A Study of DXC008 in Patients With Prostate Cancer and Other Solid Tumors

NCT ID: NCT06926283

This clinical trial is studying a new treatment called DXC008 for patients with prostate cancer and other solid tumors, including Ewing sarcoma. The main goal of the study is to find out how safe t...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, Beijing, China, Changsha, Hunan, China

Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

NCT ID: NCT06796543

This clinical trial is exploring a new way to treat children, adolescents, and young adults with metastatic sarcoma, a type of cancer that has spread from its original site to other parts of the bo...

Recruiting

Phase: NA Type: interventional Locations: Washington, District Of Columbia, United States, Baltimore, Maryland, United States

To Evaluate the Efficacy and Safety of Naxitamab in Patients With Refractory Ewing's Sarcoma (Butterfly)

NCT ID: NCT05968768

The Butterfly clinical trial is studying a new treatment called Naxitamab for patients with Ewing sarcoma, a type of cancer that affects bones or soft tissues. This trial is looking for participant...

Recruiting

Phase: PHASE2 Type: interventional Locations: Warsaw, Mazowian, Poland, Wrocław, , Poland

Adherence to a Personalized Home Exercise Program in Patients With Bone Tumor Undergoing Lower Extremity Salvage Surgery

NCT ID: NCT05779670

This clinical trial is looking at how well patients with bone tumors, like osteosarcoma or Ewing sarcoma, stick to a personalized home exercise program after having surgery on their legs. The goal ...

Recruiting

Type: observational Locations: Bologna, , Italy

Lurbinectedin in FET-Fused Tumors

NCT ID: NCT05918640

This clinical trial is studying a drug called lurbinectedin to see if it can safely and effectively treat patients with certain types of solid tumors, including Ewing sarcoma and other related canc...

Recruiting

Phase: PHASE1 Type: interventional Locations: Ann Arbor, Michigan, United States, Philadelphia, Pennsylvania, United States +5 more

Identification of Prognostic Factors and Role of Radiotherapy in Patients With Ewing Sarcoma

NCT ID: NCT06243588

This clinical trial is studying Ewing sarcoma, a type of bone cancer, to understand what factors may affect how well patients do after treatment. Researchers want to see if things like age, sex, th...

Recruiting

Type: observational Locations: Bologna, Bo, Italy

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

NCT ID: NCT06625190

This clinical trial is investigating a new treatment approach for certain solid tumors in young patients, including conditions like neuroblastoma and rhabdomyosarcoma. The treatment involves using ...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Gainesville, Florida, United States

Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma

NCT ID: NCT05734066

This clinical trial is investigating a treatment called lurbinectedin for children and young adults with a type of cancer known as Ewing sarcoma that has either come back after treatment or has not...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Memphis, Tennessee, United States +13 more

Liquid Biopsy in Ewing Sarcoma and Osteosarcoma As a Prognostic and Response Diagnostic: LEOPARD

NCT ID: NCT06068075

The LEOPARD clinical trial is looking at a new way to help doctors understand how well a patient’s treatment for certain types of cancer, specifically Ewing sarcoma and osteosarcoma, is working. Th...

Recruiting

Phase: NA Type: interventional Locations: Boston, Massachusetts, United States, Philadelphia, Pennsylvania, United States +13 more

Phase 1 Study of INBRX-109 in Subjects with Locally Advanced or Metastatic Solid Tumors Including Sarcomas

NCT ID: NCT03715933

This clinical trial is studying a new treatment called INBRX-109 for patients with advanced or metastatic solid tumors, including specific types of sarcomas and cancers like malignant pleural mesot...

Recruiting

Phase: PHASE1 Type: interventional Locations: Ann Arbor, Michigan, United States, Charlottesville, Virginia, United States +36 more

Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision)

NCT ID: NCT06094101

The PerVision trial is studying a new type of personalized cancer vaccine designed for patients with specific types of sarcomas, including Ewing sarcoma, rhabdomyosarcoma, and synovial sarcoma. Thi...

Recruiting

Phase: PHASE1 Type: interventional Locations: Frankfurt Am Main, , Germany, Freiburg, , Germany +2 more

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