A Study About the Safety of ASP3021 Eye Injections and if They Help People in Japan With Vision Loss From Age-related Macular Degeneration

NCT ID: NCT06970665

This clinical trial is looking at a new treatment called ASP3021, which is given as an injection into the eye, to see if it is safe and effective for people in Japan who have vision loss from a con...

Recruiting

Phase: PHASE3 Type: interventional Locations: Tsu Shi, Mie, Japan, Ginowan Shi, Okinawa, Japan

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette)

NCT ID: NCT05626114

The GAlette clinical trial is studying a new treatment called OpRegen for people with geographic atrophy (GA), a condition that can lead to vision loss due to age-related macular degeneration (AMD)...

Recruiting

Phase: PHASE2 Type: interventional Locations: Beverly Hills, California, United States, Cincinnati, Ohio, United States +10 more

A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

NCT ID: NCT06961370

This clinical trial is studying a new treatment called RO7669330 for people with geographic atrophy (GA), a condition that can occur due to age-related macular degeneration (AMD), which affects vis...

Recruiting

Phase: PHASE1 Type: interventional Locations: Dallas, Texas, United States, Beverly Hills, California, United States +6 more

A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration

NCT ID: NCT07029945

This clinical trial is studying a new oral medication called BRX011, taken once daily, to see if it is safe and effective for adults with geographic atrophy (GA) caused by age-related macular degen...

Not yet recruiting

Phase: PHASE1 Type: interventional

A Study to Test Different Doses of BI 1584862 in People With a Distinct Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

NCT ID: NCT06769048

This clinical trial is studying a medication called BI 1584862 to see if it can help improve vision in adults aged 55 and older who have a specific type of age-related macular degeneration (AMD) kn...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States, Beverly Hills, California, United States +43 more

A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

NCT ID: NCT06722157

This clinical trial is investigating a new treatment called BI 771716 for people aged 50 and older who have an advanced eye condition known as geographic atrophy, which is a type of age-related mac...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States, Charleston, South Carolina, United States +56 more

A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

NCT ID: NCT06779773

This clinical trial is studying how a treatment called avacincaptad pegol, also known as Izervay™, is used in real-life settings for people with geographic atrophy, a serious form of age-related ma...

Recruiting

Type: observational Locations: Colorado Springs, Colorado, United States, Altamonte Springs, Florida, United States +21 more

A Prospective, Multicenter, Open-Label, Observational Phase 4 Study to Evaluate Real-World Safety, Tolerability, and Treatment Patterns of Pegcetacoplan (Syfovre) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

NCT ID: NCT06161584

This clinical trial is studying a treatment called Pegcetacoplan (brand name Syfovre) for patients with a condition known as geographic atrophy (GA), which is often related to age-related macular d...

Recruiting

Type: observational Locations: Bakersfield, California, United States, Bakersfield, California, United States +33 more

A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

NCT ID: NCT06635148

This clinical trial is studying the long-term safety and tolerability of a treatment called JNJ-81201887 for people with Geographic Atrophy (GA), a condition related to Age-related Macular Degenera...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States, Dallas, Texas, United States +55 more

Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression

NCT ID: NCT06351657

This clinical trial is focused on studying a type of eye condition called Age-Related Macular Degeneration (AMD), specifically a form known as atrophic AMD, which does not significantly affect visi...

Recruiting

Type: observational Locations: Vienna, , Austria, Ljubljana, , Slovenia +5 more

A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of ANX007 in Participants With Geographic Atrophy (GA)

NCT ID: NCT06510816

This clinical trial is studying a new treatment for a condition called geographic atrophy (GA), which is a type of vision loss that can occur in people with age-related macular degeneration (AMD). ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Boston, Massachusetts, United States, Cleveland, Ohio, United States +142 more

Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration

NCT ID: NCT04339764

This clinical trial is studying a new treatment for a serious eye condition called dry age-related macular degeneration (AMD), specifically when it leads to a type of vision loss known as geographi...

Recruiting

Phase: PHASE1 Type: interventional Locations: Baltimore, Maryland, United States, Bethesda, Maryland, United States +1 more

High Resolution Retinal Imaging

NCT ID: NCT01866371

This clinical trial is focused on using a special imaging technique called adaptive optics scanning laser ophthalmoscope (AOSLO) to take detailed pictures of the retina, which is the light-sensitiv...

Recruiting

Type: observational Locations: Philadelphia, Pennsylvania, United States

Retinal Fundus Flavoprotein Fluorescence in Age Related Macular Degeneration

NCT ID: NCT06381596

This clinical trial is studying a condition called geographic atrophy (GA), which is a form of age-related macular degeneration (AMD) that affects the retina, the light-sensitive layer at the back ...

Recruiting

Phase: NA Type: interventional Locations: Madison, Wisconsin, United States

Evaluation of Kamuvudine-8 in Subjects With Geographic Atrophy

NCT ID: NCT06164587

This clinical trial is studying a new treatment called Kamuvudine-8 (K8) for patients with geographic atrophy (GA), a type of vision loss caused by age-related macular degeneration (AMD). The main ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Roanoke, Virginia, United States, Lexington, Kentucky, United States +3 more

A Prospective Observational Study to Assess the Reliability and Validity of the MLSDT

NCT ID: NCT06805474

This clinical trial is studying a new way to evaluate vision in people with certain eye conditions, specifically macular degeneration, geographic atrophy, and Stargardt disease. The researchers wan...

Recruiting

Type: observational Locations: Dallas, Texas, United States

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Geographic Atrophy

NCT ID: NCT05949593

This clinical trial is studying a new medication called tinlarebant (LBS-008) to see how well it works and how safe it is for people with Geographic Atrophy (GA), a type of eye disease that can lea...

Recruiting

Phase: PHASE3 Type: interventional Locations: Palo Alto, California, United States, Huntington Beach, California, United States +48 more

Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD

NCT ID: NCT05438732

This clinical trial is studying a new device called the SING implantable miniature telescope (IMT) to see how safe and effective it is for people with late-stage age-related macular degeneration (A...

Recruiting

Phase: NA Type: interventional Locations: Loma Linda, California, United States, Sarasota, Florida, United States +16 more

Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.

NCT ID: NCT06394232

This clinical trial is focused on testing a new treatment called Eyecyte-RPE™ for patients with Geographic Atrophy (GA), a serious eye condition that can lead to vision loss due to dry age-related ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Delhi, New Delhi, India, Hyderabad, Telangana, India +1 more

A PHASE IIB, RANDOMIZED, ASSESSOR-MASKED, MULTICENTER CLINICAL TRIAL TO ASSESS THE SAFETY AND EFFICACY OF SUBRETINAL IMPLANTATION OF THE CPCB-RPE1 IMPLANT IN SUBJECTS WITH ADVANCED, DRY AMD (GEOGRAPHIC ATROPHY)

NCT ID: NCT06557460

This clinical trial is studying a new treatment for people with advanced dry age-related macular degeneration (AMD), specifically a condition called geographic atrophy. The trial will test a device...

Not yet recruiting

Phase: PHASE2 Type: interventional

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Clinical Trials for Geographic Atrophy

21 Active Trials Found

A Study About the Safety of ASP3021 Eye Injections and if They Help People in Japan With Vision Loss From Age-related Macular Degeneration

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette)

A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration

A Study to Test Different Doses of BI 1584862 in People With a Distinct Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

A Prospective, Multicenter, Open-Label, Observational Phase 4 Study to Evaluate Real-World Safety, Tolerability, and Treatment Patterns of Pegcetacoplan (Syfovre) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression

A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of ANX007 in Participants With Geographic Atrophy (GA)

Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration

High Resolution Retinal Imaging

Retinal Fundus Flavoprotein Fluorescence in Age Related Macular Degeneration

Evaluation of Kamuvudine-8 in Subjects With Geographic Atrophy

A Prospective Observational Study to Assess the Reliability and Validity of the MLSDT

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Geographic Atrophy

Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD

Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.

A PHASE IIB, RANDOMIZED, ASSESSOR-MASKED, MULTICENTER CLINICAL TRIAL TO ASSESS THE SAFETY AND EFFICACY OF SUBRETINAL IMPLANTATION OF THE CPCB-RPE1 IMPLANT IN SUBJECTS WITH ADVANCED, DRY AMD (GEOGRAPHIC ATROPHY)

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