Clinical Trials for Graft Versus Host Disease

Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning

NCT ID: NCT06815003

This clinical trial is studying a new way to help prevent graft versus host disease (GVHD) in patients who are receiving a stem cell transplant from a donor. GVHD can happen when the donor cells at...

Optimizing PTCy Dose and Timing

NCT ID: NCT03983850

This clinical trial, titled "Optimizing PTCy Dose and Timing," is looking at how a lower dose of a chemotherapy drug called cyclophosphamide (PTCy) can help improve the outcomes for patients underg...

Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy Controls

NCT ID: NCT03602599

This clinical trial is studying a condition called chronic graft-versus-host disease (cGVHD), which can occur after patients receive stem cell transplants from donors. Specifically, the focus is on...

A Study of Belumosudil in People at Risk of Developing Graft-Versus-Host Disease After a Stem Cell Transplant

NCT ID: NCT07006506

This clinical trial is studying a medication called belumosudil to see if it can help prevent a condition known as graft-versus-host disease (GVHD) in people who have received a stem cell transplan...

Emapalumab With Post-Transplant Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Graft-versus-Host Disease After Donor Reduced-Intensity Hematopoietic Cell Transplant

NCT ID: NCT06996119

This clinical trial is studying a new treatment approach to help prevent a serious complication called graft-versus-host disease (GVHD) that can occur after a type of stem cell transplant known as ...

PTCY Plus uhCG/EGF for Graft Versus Host Disease Prophylaxis

NCT ID: NCT04886726

This clinical trial is studying a new approach to prevent Graft Versus Host Disease (GVHD) in patients undergoing stem cell transplants. GVHD is a condition where the transplanted cells attack the ...

Ruxolitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

NCT ID: NCT06008808

This clinical trial is studying a medication called ruxolitinib to see if it can help prevent complications after a specific type of stem cell transplant known as haploidentical peripheral blood he...

Posaconazole Tablet As Primary Prophylaxis of HSCT Patients with Gastrointestinal GVHD

NCT ID: NCT06698211

Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation

NCT ID: NCT06252870

This clinical trial is studying two different treatment plans to help prevent a serious complication called graft-versus-host disease (GVHD) in patients receiving a stem cell transplant from a dono...

Parametric Response Mapping (PRM) for the Detection of Chronic Lung Injury in Hematopoietic Cell Transplant Recipients

NCT ID: NCT05866302

This clinical trial is studying a method called Parametric Response Mapping (PRM) to help detect chronic lung injuries in patients who have received a hematopoietic cell transplant (HCT). The trial...

Relationship Between "FODMAPs" and "GVHD"

NCT ID: NCT04660487

This clinical trial is looking at the relationship between certain types of foods, known as "FODMAPs," and a condition called Graft Versus Host Disease (GVHD) in patients who have undergone a stem ...

Sequential Administration of WJ-MSCs for the Treatment of GvHD Refractory to Second Line Treatment

NCT ID: NCT06304025

This clinical trial is studying a new treatment approach for patients with Graft versus Host Disease (GVHD), a serious condition that can occur after a stem cell transplant. Researchers are specifi...

Anti T-lymphocyte Immunoglobulin With Post Transplant Cyclophosphamide to Prevent GVHD Post Allogeneic Transplantation

NCT ID: NCT03357159

This clinical trial is studying a combination of two treatments, Anti T-lymphocyte Immunoglobulin (ATLG) and Post Transplant Cyclophosphamide (PTCy), to help prevent a condition called Graft Versus...

A Prospective, Open Label, Dose-escalation, SAD/MAD, Multicenter, 24weeks, Phase I/IIa Clinical Trial to Evaluate the Safety, Tolerability and Pharmacodynamics of Investigational Product (VM-001) in Patients With Graft-versus-host Disease(GvHD)

NCT ID: NCT05276076

This clinical trial is designed to test a new treatment called VM-001 for patients with graft-versus-host disease (GvHD), a condition that can occur after a stem cell transplant where the donor's i...

Post Transplant Cyclophosphamide in Matched Unrelated Donor Stem Cell Transplantation for Hematological Malignancies

NCT ID: NCT03818334

This clinical trial is studying the use of a medication called cyclophosphamide in patients who are receiving a bone marrow transplant from a matched unrelated donor to treat blood cancers, such as...