Clinical Trials for Head and Neck Squamous Cell Carcinoma

Find clinical trials for head and neck squamous cell carcinoma. Discover research opportunities and treatment options in your area.

180 Active Trials Found

Showing 180 trials on this page

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Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in Resectable Clinically Node-negative Head and Neck Squamous Cell Carcinoma

NCT ID: NCT06323369

This clinical trial is studying the effects of combining a medication called Tislelizumab with chemotherapy, followed by surgery, for patients with a type of cancer known as Head and Neck Squamous ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, Yuexiu, China

Neoadjuvant DaRT for Locally Advanced Oral Cavity SCC

NCT ID: NCT05065346

This clinical trial is exploring a new treatment method for patients with locally advanced squamous cell carcinoma (SCC) of the oral cavity, which is a type of cancer affecting the mouth. The treat...

Not yet recruiting

Phase: NA Type: interventional Locations: Jerusalem, , Israel

FID-007 Followed by Standard of Care Surgery in Head and Neck Cancer

NCT ID: NCT06338657

This clinical trial, called FID-007 Followed by Standard of Care Surgery in Head and Neck Cancer, is exploring a new treatment for patients with a specific type of cancer known as head and neck squ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Los Angeles, California, United States, Los Angeles, California, United States

A Clinical Study of Anti-CD70 UCAR-T in Relapsed or Refractory Solid Tumors

NCT ID: NCT06383507

This clinical trial is exploring a new treatment called anti-CD70 UCAR-T cells for patients with specific types of advanced solid tumors that have not responded to previous therapies. The goal is t...

Not yet recruiting

Phase: PHASE1 Type: interventional

Tirelizumab in Combination With Carboplatin and Polymeric Micellar Paclitaxel for Neoadjuvant Therapy in cN+ HNSCC

NCT ID: NCT06366945

This clinical trial is studying a new treatment option for patients with head and neck cancer that has spread to nearby lymph nodes. The treatment combines three medicines: Tirelizumab, carboplatin...

Not yet recruiting

Phase: PHASE2 Type: interventional

Pembrolizumab in Combination With Low-dose PFas Neoadjuvant Treatment for Locally Advanced HNSCC

NCT ID: NCT05446467

This clinical trial is studying a new treatment for locally advanced head and neck squamous cell carcinoma, a type of cancer that affects the mouth, throat, or voice box. The researchers want to se...

Recruiting

Phase: PHASE2 Type: interventional Locations: Hangzhou, , China, Hangzhou, Zhejiang, China +6 more

SOTO: Treatment Sensitivity of Organoids to Predict Treatment Outcome

NCT ID: NCT05400239

The SOTO trial is investigating whether a special type of lab-grown tissue, called Patient Derived Organoids, can help predict how well patients with head and neck squamous cell carcinoma (HNSCC) w...

Recruiting

Type: observational Locations: London, , United Kingdom

Oncolytic Adenovirus TILT-123 and Avelumab for Treatment of Solid Tumors Refractory to or Progressing After Anti-PD(L)1

NCT ID: NCT05222932

This clinical trial is studying a new treatment for patients with advanced solid tumors, specifically melanoma and head and neck squamous cell carcinoma, who have not responded to or have worsened ...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Helsinki, , Finland

Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study

NCT ID: NCT02678884

This clinical trial is looking at how helpful PET scans are in planning and delivering radiation treatment for patients with head and neck cancers. The main goal is to understand if the information...

Recruiting

Phase: NA Type: interventional Locations: Toronto, Ontario, Canada

HYpofractionated, Dose-redistributed RAdiotherapy With Protons and Photons in HNSCC

NCT ID: NCT05364411

This clinical trial, called HYDRA, is studying a new way to use radiation therapy for treating advanced head and neck squamous cell carcinoma (HNSCC), a type of cancer that affects the throat and m...

Recruiting

Phase: NA Type: interventional Locations: Rotterdam, , Netherlands, Rotterdam, Zuid Holland, Netherlands

HRYZ-T101 TCR-T Cell for HPV-18 Positive Advanced Solid Tumor

NCT ID: NCT05787535

This clinical trial is studying a new treatment called HRYZ-T101 TCR-T cell therapy for patients with advanced solid tumors that are positive for HPV-18, which is a type of human papillomavirus lin...

Recruiting

Phase: PHASE1 Type: interventional Locations: Shanghai, Shanghai, China

HRYZ-T101 Injection for HPV18 Positive Solid Tumor

NCT ID: NCT05952947

This clinical trial is looking at a new treatment called HRYZ-T101 injection for patients with certain types of solid tumors that are caused by a virus known as HPV18. The trial aims to find out ho...

Recruiting

Phase: PHASE1 Type: interventional Locations: Shanghai, Shanghai, China, Shanghai, Shanghai, China

Vaccination With Flt3L, Radiation, and Poly-ICLC

NCT ID: NCT03789097

This clinical trial is exploring a new treatment approach for patients with certain types of cancer, including Non-Hodgkin's Lymphoma, Metastatic Breast Cancer, and Head and Neck Squamous Cell Carc...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States

Neoadjuvant Adebrelimab Plus Dalpiciclib in Head and Neck Squamous Cell Carcinoma

NCT ID: NCT06199271

This clinical trial is studying a combination of two medications, Adebrelimab and Dalpiciclib, to see how effective and safe they are when given to patients with advanced head and neck squamous cel...

Not yet recruiting

Phase: PHASE2 Type: interventional

Autologous T Cells Targeting HPV16 HPV18 & Survivin in Patients With R/R HPV-related Oropharyngeal Cancers

NCT ID: NCT05582590

This clinical trial is exploring a new treatment for patients with HPV-related oropharyngeal cancers that have not responded to standard therapies. The study is testing a product made from the pati...

Not yet recruiting

Phase: PHASE1 Type: interventional

Postoperative CCRT Followed by Immunotherapy in High-Risk LA HNSCC

NCT ID: NCT06170710

This clinical trial is investigating whether adding a specific type of immunotherapy, called an anti-PD-1 antibody, to standard treatment after surgery can help patients with high-risk locally adva...

Recruiting

Phase: PHASE2 Type: interventional Locations: Beijing, Beijing, China

Pirfenidone as a Radiosensitizer in the Treatment of Head and Neck Squamous Cell Carcinoma

NCT ID: NCT06142318

This clinical trial is studying the use of a medication called pirfenidone to see if it can help make radiation therapy more effective for patients with head and neck squamous cell carcinoma (HNSCC...

Recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, Guangdong, China, Jieyang, , China +3 more

A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents

NCT ID: NCT05094804

This clinical trial is studying a new treatment called OR2805, which is a type of medication known as a monoclonal antibody. It aims to see how safe and effective OR2805 is when given alone or in c...

Recruiting

Phase: PHASE1 Type: interventional Locations: Scottsdale, Arizona, United States, San Antonio, Texas, United States +1 more

Evaluating the Efficacy and Safety of Pembrolizumab Plus Standard Chemotherapy in the Neoadjuvant Treatment of Local Advanced (LA) HNSCC

NCT ID: NCT06102395

This clinical trial is studying the effectiveness and safety of a medication called pembrolizumab when combined with standard chemotherapy for patients with advanced head and neck cancer. Specifica...

Recruiting

Phase: PHASE3 Type: interventional Locations: Beijing, Beijing, China

Do Markers of Systemic Inflammatory Response and Tumor Metabolism Indicate Radioresistance in Head and Neck Cancer?

NCT ID: NCT05217212

This clinical trial is looking at ways to predict how well patients with advanced head and neck cancer will respond to radiation therapy. Specifically, researchers want to see if certain markers re...

Recruiting

Type: observational Locations: Lucerne, , Switzerland

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