Clinical Trials for Hepatocellular Carcinoma

Find clinical trials for hepatocellular carcinoma. Discover research opportunities and treatment options in your area.

414 Active Trials Found

Showing 414 trials on this page

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18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

NCT ID: NCT06503146

This clinical trial is studying a new imaging method using a special substance called 18F-FAPI-74 to help detect certain types of cancer more effectively. The goal is to find out if this new tracer...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

NCT ID: NCT06084481

This clinical trial is studying a new treatment called ABBV-400 for adults with advanced solid tumors, such as liver cancer, pancreatic cancer, and certain types of breast and ovarian cancers. The ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Grand Rapids, Michigan, United States, Durham, North Carolina, United States +64 more

Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

NCT ID: NCT06921785

This clinical trial is studying a new treatment for advanced liver cancer, known as hepatocellular carcinoma (HCC). The researchers want to see if a combination of rilvegostomig and bevacizumab, wi...

Recruiting

Phase: PHASE3 Type: interventional Locations: Barcelona, Spain, Rochester, Minnesota, United States +106 more

Gecacitinib Combined With Donafenib and PD-1 Inhibitor as Immune Rechallenge Therapy for Unresectable Hepatocellular Carcinoma

NCT ID: NCT07157306

This Phase II study is testing a new three-drug approach for people with unresectable hepatocellular carcinoma (liver cancer that cannot be removed by surgery) who have not responded to prior immun...

Not yet recruiting

Phase: PHASE2 Type: interventional

A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular Carcinoma

NCT ID: NCT06679985

This clinical trial is studying a new treatment for patients with a specific type of liver cancer called hepatocellular carcinoma (HCC), which is either too advanced or cannot be removed by surgery...

Recruiting

Phase: PHASE2 Type: interventional Locations: Jackson, Mississippi, United States, Duarte, California, United States +23 more

Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells

NCT ID: NCT07148050

This clinical trial is studying a new type of immunotherapy treatment for children and young adults with certain hard-to-treat solid tumors outside the brain, including liver cancers and other spec...

Not yet recruiting

Phase: PHASE1 Type: interventional

Y-90 Treatment Response

NCT ID: NCT07145801

This clinical trial is studying a new way to check how well a specific liver cancer treatment called transarterial radioembolization (TARE) is working. TARE is used to treat a common type of liver ...

Not yet recruiting

Phase: PHASE2 Type: interventional

A Phase I Clinical Study of Intratumoral Injection Oncolytic Vaccinia Virus GC001 in Patient With Advanced Solid Tumors

NCT ID: NCT06508307

This clinical trial is investigating a new treatment called GC001, which is an oncolytic virus designed to target and help fight advanced solid tumors, such as sarcoma, cervical cancer, colon cance...

Recruiting

Phase: PHASE1 Type: interventional Locations: Zhengzhou, Henan, China

A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-Pugh B7 and B8 Cirrhosis

NCT ID: NCT06096779

This clinical trial is testing two medications, atezolizumab and bevacizumab, to see how safe and effective they are for treating patients with a type of liver cancer called hepatocellular carcinom...

Recruiting

Phase: PHASE2 Type: interventional Locations: Chicago, Illinois, United States, Orange, California, United States +65 more

TACE Combined With Anti-PD-1 Antibody in Patients With Advanced Hepatocellular Carcinoma: Study on Efficacy and Immune Microenvironment

NCT ID: NCT07100405

This clinical trial is studying a new treatment approach for people with advanced liver cancer (hepatocellular carcinoma). It looks at how well a combination of two therapies works: TACE, a procedu...

Recruiting

Type: observational Locations: Shanghai, Shanghai, China

A Single-Arm, Multicenter, Exploratory Clinical Study of TACE Combined With Iparomlimab and Tuvonralimab Injection (QL1706) and Lenvatinib for Perioperative Treatment of Resectable Hepatocellular Carcinoma

NCT ID: NCT07131501

This clinical trial is studying a new combination of treatments for people with a type of liver cancer called hepatocellular carcinoma (HCC) that can be removed by surgery. The study is testing whe...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Nanjing, Jiangsu, China

A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)

NCT ID: NCT06109272

This clinical trial is studying two investigational drugs, livmoniplimab and budigalimab, to see how well they work together in treating patients with hepatocellular carcinoma (HCC), a serious type...

Recruiting

Phase: PHASE2 Type: interventional Locations: Saint Louis Park, Minnesota, United States, Merriam, Kansas, United States +45 more

STRIDE (Durvalumab + Tremelimumab) With Lenvatinib vs STRIDE Alone in Unresectable Hepatocellular Carcinoma

NCT ID: NCT06880523

The STRIDE clinical trial is studying a combination of three medications to see if they can improve treatment outcomes for patients with a type of liver cancer called unresectable hepatocellular ca...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Vancouver, British Columbia, Canada, Calgary, Alberta, Canada

68Ga-PSMA-11 PET-directed Radioligand Therapy in Metastatic Hepatocellular Carcinoma (HCC)

NCT ID: NCT06852820

This clinical trial is looking at a new treatment for liver cancer, specifically a type called metastatic hepatocellular carcinoma (HCC). The treatment being studied is a drug named 177Lu-PSMA-617,...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Cleveland, Ohio, United States

A Study of MGC026 in Participants With Advanced Solid Tumors

NCT ID: NCT06242470

This clinical trial is investigating a new treatment called MGC026 for adults with advanced solid tumors, which are types of cancer that have spread or cannot be removed through surgery. The study ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States, Los Angeles, California, United States +10 more

TACE Combined With Lenvatinib and PD-1 Inhibitor for Ruptured Hepatocellular Carcinoma

NCT ID: NCT06740370

This clinical trial is looking at a new treatment approach for patients with a specific type of liver cancer called hepatocellular carcinoma (HCC) that has ruptured, causing bleeding. The study is ...

Recruiting

Phase: NA Type: interventional Locations: Beijing, None Selected, China

CT-guided Localization for Micro Hepatocellular Carcinoma Before Surgical Resection

NCT ID: NCT05433467

This clinical trial is looking at a new way to locate tiny liver tumors called micro hepatocellular carcinoma before surgery. These tumors are less than 1 centimeter in size and can be tricky to fi...

Recruiting

Phase: NA Type: interventional Locations: Yangzhou, Jiangsu, China

Phase 1, Single-site, Single-arm, Clinical Imaging, and Blood-based Biomarker Trial Utilizing 18F-FSPG PET to Guide Therapy in Hepatocellular Carcinoma

NCT ID: NCT07116486

This clinical trial is studying a new way to help guide treatment for people with hepatocellular carcinoma (HCC), which is a type of liver cancer. The researchers want to see how a special imaging ...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

AHCC® as Immune Modulator in Cancer Patients Treated With Immunotherapy

NCT ID: NCT07118735

This clinical trial is studying whether a natural supplement called AHCC® can help boost the effects of immunotherapy in people with liver cancer, specifically a type called hepatocellular carcinom...

Not yet recruiting

Phase: NA Type: interventional Locations: Tainan, Taiwan

T-Cell Therapy (ECT204) in Adults With Advanced HCC

NCT ID: NCT04864054

This clinical trial is studying a new treatment called ARTEMIS® ECT204 T-cell therapy for adults with advanced liver cancer, specifically a type called hepatocellular carcinoma (HCC). The aim is to...

Recruiting

Phase: PHASE2 Type: interventional Locations: Duarte, California, United States, Westwood, Kansas, United States +5 more

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