Clinical Trials for Hypophosphatasia

Phase 3 Study of ALXN1850 in Treatment-Naïve Pediatric Participants With HPP

NCT ID: NCT06079359

This clinical trial is studying a new treatment called ALXN1850 for children with a condition known as Hypophosphatasia (HPP), which affects bone development. The main goal is to see how well ALXN1...

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

NCT ID: NCT01793168

The Coordination of Rare Diseases at Sanford (CoRDS) is a clinical trial aimed at creating a large, centralized registry for individuals affected by rare diseases. This registry helps connect patie...

Early Check: Expanded Screening in Newborns

NCT ID: NCT03655223

Natural History Study of Patients With Hypophosphatasia (HPP)

NCT ID: NCT02237625

This clinical trial is studying Hypophosphatasia (HPP), a rare genetic disorder that affects how bones and teeth develop. People with HPP have a problem with a specific enzyme that leads to weak bo...

A Prospective Sub-Study of the Global Hypophosphatasia Registry

NCT ID: NCT05234567

This clinical trial is studying a condition called hypophosphatasia (HPP), which affects the bones and can start in childhood. The trial is specifically looking at children and young adults who wer...

Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia

NCT ID: NCT06015750

This clinical trial, called STRENSIQ®, is studying a treatment approach for people with a condition known as hypophosphatasia, which affects bone health. The main goal of the trial is to see how we...

Characteristics of Hypophosphatasia in Adult Patients in Rheumatology and Their Value in Developing an Algorithm to HPP-diagnosis - the COHIR Multi-center Study

NCT ID: NCT06574282

The COHIR Multi-center Study is looking at a condition called hypophosphatasia, which affects how the body processes a substance called phosphate that's important for bone health. This study is spe...

Prospective, Longitudinal, Observational Registry of Adult Patients with Hypophosphatasia (REG-HYPO)

NCT ID: NCT05596539

This clinical trial, called REG-HYPO, is studying adults with a condition known as hypophosphatasia, which affects bone health and can cause problems like pain and fractures. The goal of the study ...

United States Hypophosphatasia Molecular Research Center

NCT ID: NCT05062629

The United States Hypophosphatasia Molecular Research Center is conducting a clinical trial to learn more about a condition called hypophosphatasia, which affects the bones and teeth. This study is...

Characteristics of Hypophosphatasia in Adult Patients in Rheumatology

NCT ID: NCT06161142

This clinical trial is looking into a condition called hypophosphatasia, which is often missed or misdiagnosed in adults. The study aims to find out how common hypophosphatasia is among adult patie...