Clinical Trials for Leukemia

Allogeneic CD7 CAR γδ T Cells Therapy Recurrent/Refractory Leukemia

NCT ID: NCT07120607

This clinical trial is testing a new treatment for certain types of leukemia, specifically T-cell acute lymphoblastic leukemia (T-ALL), T-cell lymphoma, and some forms of acute myeloid leukemia (AM...

Natural History Study to Determine Drug Metabolism Phenotype and Appropriate Germline Source DNA in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant

NCT ID: NCT06856226

This clinical trial is studying how our genes affect how medications are processed in patients who receive a special treatment called allogeneic hematopoietic stem cell transplant (HSCT). After thi...

A Pediatric and Young Adult Trial of Genetically Modified T Cells Directed Against CD22 for Relapsed/Refractory Leukemia or Lymphoma

NCT ID: NCT04571138

This clinical trial is exploring a new treatment for children and young adults with leukemia or lymphoma that has not responded to other treatments, including chemotherapy. The study is using a spe...

Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

NCT ID: NCT06578247

This clinical trial is studying the effects of a medication called Quizartinib compared to a placebo (a substance with no active medication) when used alongside standard chemotherapy in patients wh...

Cladribine Plus Low Dose Cytarabine (LDAC) Alternating With Decitabine in Patients With Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS)

NCT ID: NCT01515527

This clinical trial is studying a combination of three medications—cladribine, low-dose cytarabine (LDAC), and decitabine—to see if they can help control acute myeloid leukemia (AML) or high-risk m...

A Clinical Study of BT02 in Patients With Relapsed or Refractory Hematologic Malignancies

NCT ID: NCT07107204

This clinical trial is studying a new treatment called BT02 for adults aged 18 to 70 who have certain blood cancers, such as leukemia, lymphoma, or multiple myeloma, that have come back after previ...

Cardiovascular Risk in Children With Chronic Conditions Study

NCT ID: NCT07086989

This study is looking at children and young adults with long-term health conditions that might raise their chances of heart and blood vessel problems early in life. The researchers want to understa...

Effectiveness and Safety of Blinatumomab and Donor Lymphocyte Infusion in Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation for High-risk Ph Negative B Cell Acute Lymphoblastic Leukemia

NCT ID: NCT07105579

This clinical trial is studying a new approach to help people with a type of blood cancer called high-risk Philadelphia chromosome-negative B cell acute lymphoblastic leukemia (Ph-negative B-ALL) s...

A Prospective Trial of Dalbavancin-Based Prophylaxis in Children and Adolescents With High-Risk Leukemia

NCT ID: NCT06810583

This clinical trial is looking at the use of a medication called dalbavancin to help prevent serious bacterial infections in children and young adults who are being treated for high-risk leukemia, ...

Effects of Using a Storybook, to Explain Leukemia to Children Versus the Standard Child Life Intervention, on Parental Stress.

NCT ID: NCT06360718

This clinical trial is studying how a special storybook can help reduce stress for parents of children who have just been diagnosed with leukemia, compared to the usual support they receive. The re...

Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia

NCT ID: NCT05645718

This clinical trial is investigating a new treatment approach for young patients with relapsed B-cell acute lymphoblastic leukemia (B-ALL), a type of blood cancer. The study is testing a combinatio...

Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

NCT ID: NCT00736749

This clinical trial is focused on following up with patients who have been part of studies conducted by the Children's Oncology Group, which is a group that researches treatments for children's can...

Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation

NCT ID: NCT06138587

This clinical trial is looking at a new treatment method called preemptive CIML NK cell therapy, designed to help prevent the return of certain types of blood cancers, including acute myeloid leuke...

Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant

NCT ID: NCT04898790

This clinical trial is studying how physical activity can help improve thinking and memory skills in older adults who have recently undergone a stem cell transplant for blood cancers like leukemia ...

Mosaic Trial for Stem Cell Transplant Recipients

NCT ID: NCT06960993

The Mosaic Trial is a research study designed to see if a special website can help adults with blood cancer who are getting stem cell transplants. The study will compare the experiences of patients...

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

NCT ID: NCT05237986

This clinical trial is looking at how CAR T-cell therapy, a new treatment for blood cancers like leukemia and lymphoma, may affect thinking and memory in children and young adults between the ages ...

A Multicenter Trial Evaluating Efficacy and Safety of A Reduced Venetoclax Exposure To Seven Days Versus Standard Continuous Venetoclax Exposure Combined With Azacitidine in Treatment Naïve Subjects With Acute Myeloid Leukemia Who Are Ineligible for Intensive Induction

NCT ID: NCT07082452

This clinical trial is testing a new way to give two medicines—venetoclax and azacitidine—to people with a type of blood cancer called acute myeloid leukemia (AML). Usually, these medicines are giv...

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT ID: NCT06001788

This clinical trial is studying a new treatment called ziftomenib, which is being tested in combination with standard therapies for patients with relapsed or refractory acute myeloid leukemia (AML)...

Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing

NCT ID: NCT03226704

A Music Therapy Study for Blood Cancer Survivors With Cognitive Difficulties

NCT ID: NCT07052916

This study is looking at whether music therapy delivered through telehealth (online sessions) can help improve thinking skills like memory and attention in people who have survived blood cancers su...