Clinical Trials for Locally Advanced Pancreatic Adenocarcinoma

Find clinical trials for locally advanced pancreatic adenocarcinoma. Discover research opportunities and treatment options in your area.

18 Active Trials Found

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Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer

NCT ID: NCT04172532

This clinical trial is studying a new anti-cancer drug called M3814 (Peposertib) to see how it works when combined with radiation therapy for patients with locally advanced pancreatic cancer. The g...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chicago, Illinois, United States, Lebanon, New Hampshire, United States +46 more

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advanced or Metastatic Pancreatic Cancer

NCT ID: NCT06381154

This clinical trial is studying a new treatment approach for patients with pancreatic cancer that cannot be surgically removed. The treatment combines a light-activated drug called verteporfin with...

Recruiting

Phase: PHASE2 Type: interventional Locations: Rochester, Minnesota, United States

Neoadjuvant Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

NCT ID: NCT05825066

This clinical trial is studying a new treatment approach for patients with certain types of pancreatic cancer that are difficult to remove through surgery. Specifically, it looks at the effects of ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Winston Salem, North Carolina, United States

Phase I/IIa Study: RR001 Administered Following Chemotherapy Cycles for Patients With Locally Advanced Pancreatic Carcinoma

NCT ID: NCT06861452

This clinical trial is studying a new treatment called RR001, which is a type of cell-based gene therapy. It is being tested in patients with locally advanced pancreatic cancer, which means the can...

Recruiting

Phase: PHASE1 Type: interventional Locations: Modena, , Italy

First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancer

NCT ID: NCT04665947

This clinical trial is studying a new treatment approach for patients with advanced pancreatic cancer, specifically those whose cancer cannot be surgically removed (locally advanced) or has spread ...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Sacramento, California, United States

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

NCT ID: NCT06998940

This clinical trial is investigating whether adding a medication called panitumumab to standard chemotherapy can help patients with advanced pancreatic cancer. The study is focused on patients whos...

Not yet recruiting

Phase: PHASE3 Type: interventional

A Study of High Dose Radiation Therapy for Locally Advanced Pancreatic Cancer That Responded to Initial Chemotherapy Treatment

NCT ID: NCT06453486

This clinical trial is exploring the effects of high-dose radiation therapy on patients with locally advanced pancreatic cancer who have shown a positive response to initial chemotherapy. The main ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Toronto, Ontario, Canada

PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC)

NCT ID: NCT06673017

This clinical trial, titled PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC), is investigating a new treatment for patients with pancreatic cancer that is either borderline resectable or locally ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Newport Beach, California, United States, Seattle, Washington, United States +1 more

Sequential Treatment With GEMBRAX and Then FOLFIRINOX Followed by Stereotactic MRI-guided Radiotherapy in Patients With Locally Advanced Pancreatic Cancer

NCT ID: NCT04570943

This clinical trial is investigating a new treatment approach for patients with locally advanced pancreatic cancer, which is a type of cancer that cannot be removed through surgery. The study is te...

Recruiting

Phase: PHASE2 Type: interventional Locations: Villejuif, , France, Rennes, , France +10 more

Acoustic Cluster Therapy (ACT) with Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer

NCT ID: NCT06850623

This clinical trial is studying a new treatment option called Acoustic Cluster Therapy (ACT) combined with chemotherapy for patients with locally advanced pancreatic cancer. The goal is to see if t...

Not yet recruiting

Phase: PHASE2 Type: interventional

Stereotactic Body Radiation and Tumor Treating Fields for Locally Advanced Pancreas Cancer

NCT ID: NCT05679674

This clinical trial is looking at a new treatment approach for people with locally advanced pancreatic cancer. The goal is to see if combining chemotherapy with a special type of radiation therapy,...

Recruiting

Phase: NA Type: interventional Locations: Miami, Florida, United States

Standard or Prolonged Neoadjuvant Chemotherapy Before Surgery for BR/LAPC

NCT ID: NCT06714604

This clinical trial is investigating the best duration of chemotherapy before surgery for patients with borderline or locally advanced pancreatic cancer. The researchers want to compare two approac...

Recruiting

Phase: PHASE3 Type: interventional Locations: Gothenburg, Vgr, Sweden

Calaspargase Pegol-Mnkl and Cobimetinib for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer

NCT ID: NCT05034627

This clinical trial is studying a new treatment approach for patients with locally advanced or metastatic pancreatic cancer, which means the cancer has either spread to nearby tissues or to other p...

Recruiting

Phase: PHASE1 Type: interventional Locations: Portland, Oregon, United States

OncoSil Pancreatic Cancer Post-marketing Clinical Registry - Italy

NCT ID: NCT06399172

The OncoSil Pancreatic Cancer Post-marketing Clinical Registry in Italy is a study designed to look at how well the OncoSil™ device works for patients with locally advanced pancreatic cancer that c...

Not yet recruiting

Type: observational

Pressure Enabled Intrapancreatic Delivery of SD-101 With Checkpoint Blockade for Locally Advanced Pancreatic Adenocarcinoma

NCT ID: NCT05607953

This clinical trial is investigating a new treatment approach for patients with locally advanced pancreatic cancer, which means the cancer is not yet spread widely but cannot be removed through sur...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Locally Advanced Pancreatic Cancer After Systemic Therapy: Ablative MR-guided Radiotherapy

NCT ID: NCT06272162

This clinical trial is studying a new treatment for patients with locally advanced pancreatic cancer, specifically looking at how an advanced type of radiation therapy called MR-guided radiotherapy...

Not yet recruiting

Phase: NA Type: interventional Locations: Utrecht, , Netherlands, Nijmegen, , Netherlands +2 more

Survival, Quality of Life and Resectability in Locally Advanced Pancreatic Cancer

NCT ID: NCT05356039

This clinical trial is studying how well different treatments work for people with locally advanced pancreatic cancer, which means the cancer is not yet spread to distant parts of the body but is s...

Recruiting

Type: observational Locations: Umeå, , Sweden

PREOPANC-4 Implementation Program for Locally Advanced Pancreatic Cancer

NCT ID: NCT05524090

The PREOPANC-4 study is focused on improving the treatment of locally advanced pancreatic cancer (LAPC) in the Netherlands. This clinical trial is evaluating an international standard of care that ...

Recruiting

Type: observational Locations: Amsterdam, Noord Holland, Netherlands

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