Clinical Trials for Low Grade Glioma

Find clinical trials for low grade glioma. Discover research opportunities and treatment options in your area.

7 Active Trials Found

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A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

NCT ID: NCT04166409

This clinical trial is studying two different treatments for patients with low-grade glioma, a type of brain tumor. The trial compares a new drug called selumetinib, which may help kill tumor cells...

Recruiting

Phase: PHASE3 Type: interventional Locations: New Haven, Connecticut, United States, Durham, North Carolina, United States +139 more

Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy

NCT ID: NCT03952598

This clinical trial is focused on studying a substance called 2-hydroxyglutarate (2-HG) in the brains of people with gliomas, a type of brain cancer that can be more aggressive if it has certain ge...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas

NCT ID: NCT06712875

This clinical trial is investigating a new treatment approach for children and young adults with specific types of brain tumors called gliomas that have certain genetic changes (BRAF alterations). ...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Chicago, Illinois, United States +1 more

BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas

NCT ID: NCT03749187

This clinical trial is investigating the combination of two treatments, BGB-290 and temozolomide, for young people with specific types of brain tumors called IDH1/2-mutant gliomas. These tumors can...

Recruiting

Phase: PHASE1 Type: interventional Locations: New Haven, Connecticut, United States, Durham, North Carolina, United States +15 more

Post-Operative Dosing of Dexamethasone in Patients with Brain Tumors After a Craniotomy, PODS Trial

NCT ID: NCT06132685

The PODS Trial is a clinical study looking at how to safely reduce the amount of a medication called dexamethasone that patients take after having surgery to remove a brain tumor. Dexamethasone is ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Atlanta, Georgia, United States

A Vaccine Trial for Low Grade Gliomas

NCT ID: NCT02358187

This clinical trial is studying a new vaccine designed to help children with low-grade gliomas, which are slow-growing brain tumors that cannot be surgically removed. The vaccine aims to boost the ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Pittsburgh, Pennsylvania, United States

Feasibility of Individualized, Model-guided Optimization of Proton Beam Treatment Planning in Patients With Low Grade Glioma

NCT ID: NCT05964569

This clinical trial is exploring a new way to plan radiation treatment for patients with low-grade gliomas, which are slow-growing brain tumors. The study aims to see if a personalized approach, us...

Recruiting

Phase: PHASE2 Type: interventional Locations: Heidelberg, , Germany

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