Clinical Trials for Lupus Nephritis

Find clinical trials for lupus nephritis. Discover research opportunities and treatment options in your area.

63 Active Trials Found

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Chimeric Antigen Receptors T Cells for Refractory/Recurrent Lupus Nephritis in Children

NCT ID: NCT06904729

This clinical trial is studying a new treatment called CAR T cell therapy for children with lupus nephritis, a serious kidney condition caused by lupus. The aim is to see how safe and effective thi...

Recruiting

Phase: PHASE3 Type: interventional Locations: Guangzhou, Guangdong, China

Lupus Landmark Study: A Prospective Registry and Biorepository

NCT ID: NCT05934149

The Lupus Landmark Study is a clinical trial designed to gather important information about systemic lupus erythematosus (SLE), including its effects on the kidneys (lupus nephritis) and the brain ...

Recruiting

Type: observational Locations: New York, New York, United States, Chicago, Illinois, United States +21 more

Systemic Immune Inflammatory Index in Systemic Lupus Erythematosus

NCT ID: NCT06796569

This clinical trial is studying the relationship between a specific index called the systemic immune-inflammation index and the activity of systemic lupus erythematosus (SLE), as well as a serious ...

Recruiting

Type: observational Locations: Sohag, , Egypt

CD19/BCMA CAR-T Cell Therapy for Refractory/Relapsed Lupus Nephritis

NCT ID: NCT06785519

This clinical trial is studying a new treatment called CD19/BCMA CAR-T cell therapy for patients with lupus nephritis, a serious condition caused by systemic lupus erythematosus (SLE) that can lead...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Hangzhou, Zhejiang, China

A Phase 1 Study of ADI-001 in Autoimmune Disease

NCT ID: NCT06375993

This clinical trial is testing a new treatment called ADI-001 for patients with lupus nephritis, a kidney problem that can occur in people with lupus, an autoimmune disease. The goal of this study ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Manhasset, New York, United States

The Effect of Mycophenolate Mofetil and Cyclophosphamide on the Lymphocyte Subsets in Patients With Proliferative Lupus Nephritis

NCT ID: NCT02954939

This clinical trial is studying how two different treatments affect the immune system in patients with a condition called proliferative lupus nephritis, which is a serious kidney problem caused by ...

Recruiting

Phase: NA Type: interventional Locations: Hong Kong, , Hong Kong

VIBRANT: VIB4920 for Active Lupus Nephritis

NCT ID: NCT05201469

The VIBRANT clinical trial is studying a new treatment called VIB4920 for people with active lupus nephritis, a condition where the immune system attacks the kidneys. This study is designed to see ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Columbus, Ohio, United States, Charleston, South Carolina, United States +16 more

SGLT2 Inhibitor in Lupus Nephritis Patients With Chronic Kidney Disease

NCT ID: NCT06155604

This clinical trial is studying the effects of a medication called SGLT2 inhibitor in patients with lupus nephritis (LN) who also have chronic kidney disease (CKD). Lupus nephritis is a condition t...

Recruiting

Phase: PHASE2 Type: interventional Locations: Hong Kong, , Hong Kong, Hong Kong, , Hong Kong

US Zamto-cel Autoimmune Diseases

NCT ID: NCT06708845

The US Zamto-cel Autoimmune Diseases trial is studying a new treatment called zamtocabtagene autoleucel (zamto-cel) for patients with difficult-to-treat autoimmune diseases, specifically lupus neph...

Not yet recruiting

Phase: PHASE1 Type: interventional

KYSA-3: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis

NCT ID: NCT06342960

The KYSA-3 trial is studying a new type of treatment called anti-CD19 Chimeric Antigen Receptor T-Cell (CAR T) therapy for people who have lupus nephritis that hasn’t responded to other treatments....

Recruiting

Phase: PHASE1 Type: interventional Locations: Düsseldorf, , Germany, Erlangen, , Germany +7 more

Universal CAR-T Cell Therapy for Refractory Lupus Nephritis

NCT ID: NCT06681337

This clinical trial is studying a new type of treatment for people with lupus nephritis, a serious kidney condition caused by lupus that hasn't responded well to other treatments. The researchers w...

Not yet recruiting

Phase: EARLY_PHASE1 Type: interventional

Study to Assess Real-world Effectiveness of Belimumab for Treatment of Adults With LN

NCT ID: NCT06527872

The OBSErve-LN study is looking at how well a medication called belimumab works in real-life situations for adults with a condition known as lupus nephritis (LN). This study is important because it...

Recruiting

Type: observational Locations: Charlotte, North Carolina, United States

Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE)

NCT ID: NCT06350110

This clinical trial is investigating a new treatment using a type of engineered immune cells called CAR T cells to help patients with systemic lupus erythematosus (SLE) who have not responded to ot...

Recruiting

Phase: PHASE1 Type: interventional Locations: Shanghai, , China, Beijing, Beijing, China

Renal Arterial Resistive Index as a Noninvasive Biomarker of Disease Activity in Lupus Nephritis Patients

NCT ID: NCT06631404

This clinical trial is studying a new way to monitor kidney health in patients with lupus nephritis, a condition that can occur in people with systemic lupus erythematosus (SLE), an autoimmune dise...

Recruiting

Type: observational Locations: Sohag, , Egypt

Association Between Neuropathy and Some Autoantibodies in Systemic Lupus Erythematosus (SLE) Patients

NCT ID: NCT06610422

This clinical trial is looking at how often patients with a condition called lupus nephritis experience nerve problems, known as peripheral neuropathy. It also aims to see how useful certain blood ...

Not yet recruiting

Type: observational

A Study of Telitacicept in Lupus Nephritis

NCT ID: NCT05680480

This clinical trial is looking at a new treatment called Telitacicept for adults with lupus nephritis, which is a serious condition that affects the kidneys in people with lupus. The main goal of t...

Recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, Guangdong, China, Guangzhou, Guangdong, China +44 more

The Relation Between Serum Zinc and Lupus Nephritis

NCT ID: NCT06564181

This clinical trial is looking to understand the connection between zinc levels in the blood and a condition called lupus nephritis, which affects the kidneys. Researchers want to find out how comm...

Not yet recruiting

Type: observational

Urinary G3BP as a Novel Biomarker in Lupus Nephritis

NCT ID: NCT06520670

This clinical trial is exploring a new test called urinary Galectin-3 binding protein (u-Gal-3BP), which may help doctors understand and manage lupus nephritis, a kidney condition that can occur in...

Not yet recruiting

Type: observational

KYSA-1: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis

NCT ID: NCT05938725

The KYSA-1 clinical trial is investigating a new treatment called anti-CD19 Chimeric Antigen Receptor T-Cell (CAR T) therapy for patients with a severe form of lupus nephritis, a kidney condition c...

Recruiting

Phase: PHASE1 Type: interventional Locations: Worcester, Massachusetts, United States, Philadelphia, Pennsylvania, United States +4 more

Effectiveness of Mycophenolate Mofetil Combined With Tacrolimus for Steroid Tapering in Systemic Lupus Erythematosus

NCT ID: NCT05916781

This clinical trial is studying whether a combination of two medications, mycophenolate mofetil (MMF) and tacrolimus (TAC), can help patients with lupus nephritis maintain their health after reduci...

Recruiting

Phase: PHASE4 Type: interventional Locations: Beijing, , China, Beijing, Beijing, China

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