Clinical Trials for Major Depressive Disorder (MDD)

Find clinical trials for major depressive disorder (mdd). Discover research opportunities and treatment options in your area.

45 Active Trials Found

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Personalized Accelerated Intermittent Theta Burst Stimulation for Post-Acute Suicidal Ideation

NCT ID: NCT07025720

This clinical trial is studying a new, fast treatment called transcranial magnetic stimulation (TMS) to help people who have depression and recent thoughts of suicide. TMS is a non-invasive procedu...

Not yet recruiting

Phase: NA Type: interventional

Theta-Burst Stimulation to Treat Depression

NCT ID: NCT07033780

This clinical trial is studying a new way to help people with Major Depressive Disorder (MDD), a type of depression. It is testing a treatment called intermittent theta-burst stimulation (iTBS), wh...

Recruiting

Phase: PHASE1 Type: interventional Locations: Toronto, Ontario, Canada

Moving on After Breast Cancer Trial for Depressed Breast Cancer Survivors in Pakistan

NCT ID: NCT07015944

The "Moving on After Breast Cancer" trial is a study designed to help women who have survived breast cancer and are dealing with depression. Breast cancer is a common illness among women, and many ...

Not yet recruiting

Phase: NA Type: interventional Locations: Karachi, Sindh, Pakistan

Assessment of Whether Telehealth Family Psychoeducation for Major Depressive Disorder is Doable

NCT ID: NCT07014241

This clinical trial is exploring a new way to support individuals with Major Depressive Disorder (MDD) and their families through telehealth family psychoeducation (FPE). The goal is to see how wel...

Not yet recruiting

Phase: NA Type: interventional Locations: Bakewell, Northern Territory, Australia, Palmerston, Northern Territory, Australia

Switching Medication and Augmentation Strategies for SSRI-Resistant Adolescent Depression（SMART-I)

NCT ID: NCT07011693

The SMART-I trial is studying how well common antidepressants work for teenagers aged 12 to 17 who are dealing with major depressive disorder (MDD) but did not improve after their first treatment w...

Not yet recruiting

Phase: PHASE4 Type: interventional Locations: Chongqing, Chongqing, China

Cognitive Rehabilitation for Veterans With MDD-related Cognitive Functioning Deficits

NCT ID: NCT06728774

This clinical trial is exploring a new way to help veterans who have experienced Major Depressive Disorder (MDD) and are still facing difficulties with thinking, memory, and attention even after th...

Recruiting

Phase: NA Type: interventional Locations: Portland, Oregon, United States

Lifestyle Interventions to Prevent Cognitive Deficits in Subjects With Depressive Symptoms: From Mechanisms to Clinical Practice

NCT ID: NCT07009223

This clinical trial is looking at whether making lifestyle changes can help improve mood and memory in people aged 50 to 80 who have symptoms of depression but do not show signs of cognitive declin...

Not yet recruiting

Phase: NA Type: interventional Locations: Brescia, , Italy

Evaluation of the Concordance Between Measures Obtained by a Medical Device for Emotional Monitoring (EMOCARE) and the Patient Health Questionnaire (PHQ-9) Score in Patients With Mild to Moderate Depressive Episode

NCT ID: NCT06601140

The EMOCARE clinical trial is studying a new emotional monitoring software designed to help people with mild to moderate depression. The main goal is to see if the results from this software match ...

Recruiting

Phase: NA Type: interventional Locations: Nantes, , France, Laxou, , France +3 more

IWLS for Major Depressive Disorder: An Open-Label Study of Safety, Tolerability, and Efficacy

NCT ID: NCT06922812

This clinical trial is looking at a new treatment method for people with Major Depressive Disorder (MDD) using a technique called Intermittent White Light Stimulation (IWLS). The goal is to see if ...

Recruiting

Phase: NA Type: interventional Locations: São Paulo, Sp, Brazil

Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

NCT ID: NCT06830044

This clinical trial is studying a medication called milsaperidone to see how well it works and how safe it is for people who are struggling with Major Depressive Disorder (MDD). Milsaperidone will ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Little Rock, Arkansas, United States, Richardson, Texas, United States

Physical Activity-based Intervention in Depressed Patients: Clinical, Neurophysiological, Epigenetic and Metabolic Correlates

NCT ID: NCT06989944

This clinical trial is looking to understand how a structured physical activity program can help adults with major depressive disorder (MDD). The study will explore whether participating in regular...

Recruiting

Phase: NA Type: interventional Locations: Milano, , Italy, Pescara, , Italy +2 more

Implementation of a Multiple Intervention to Promote Healthy Lifestyles in Patients With Depression

NCT ID: NCT06990035

This clinical trial is exploring whether a combination of learning about the Mediterranean diet and engaging in physical activity can help reduce symptoms of major depressive disorder (MDD). The Me...

Not yet recruiting

Phase: NA Type: interventional Locations: Brescia, , Italy

Study to Evaluate Efficacy and Safety of Ropanicant in MDD Patients

NCT ID: NCT06836063

This clinical trial is designed to test a medication called Ropanicant for people suffering from Major Depressive Disorder (MDD). The main goal is to see how effective Ropanicant is at two differen...

Not yet recruiting

Phase: PHASE2 Type: interventional

Sedation and Guided Education for Depression Study

NCT ID: NCT06705270

The Sedation and Guided Education for Depression Study is a clinical trial aimed at understanding how the way we educate patients about a specific treatment affects their response to that treatment...

Not yet recruiting

Phase: NA Type: interventional

Home-Based tDCS Treatment Of Major Depressive Disorder

NCT ID: NCT06976697

The REACH-tDCS study is exploring a new way to treat Major Depressive Disorder (MDD) using a noninvasive brain stimulation method called Sooma tDCS. This treatment can be done at home, which means ...

Recruiting

Phase: NA Type: interventional Locations: New York, New York, United States

Physical Therapy for Depression Quality of Life (Pilot Study Protocol)

NCT ID: NCT06983405

This clinical trial, called the "Physical Therapy for Depression Quality of Life Pilot Study," is exploring how physical therapy can help improve the quality of life for adults with Major Depressiv...

Not yet recruiting

Phase: NA Type: interventional Locations: Zaragoza, Aragón, Spain, Zaragoza, , Spain

Home-Based tDCS for Depression in BPD

NCT ID: NCT06972368

This clinical trial is investigating whether a treatment called home-based transcranial direct current stimulation (tDCS) can help reduce symptoms of depression in adults with Borderline Personalit...

Not yet recruiting

Phase: NA Type: interventional

Efficacy of Dextromethorphan-Bupropion Versus SSRIs in the Treatment of Major Depressive Disorder

NCT ID: NCT06957223

This clinical trial is looking at how effective a combination of two medications, dextromethorphan and bupropion, is for treating major depressive disorder (MDD) compared to standard antidepressant...

Recruiting

Phase: NA Type: interventional Locations: Nowshera, Kpk, Pakistan, Nowshera, Kpk, Pakistan

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

NCT ID: NCT06793397

This clinical trial is studying a new treatment called CYB003 for people with Major Depressive Disorder (MDD). The goal is to see how well CYB003 works, how safe it is, and how well patients tolera...

Not yet recruiting

Phase: PHASE3 Type: interventional

A Trial of Dextromethorphan and Bupropion Sustained-Release Tablets in Patients With Major Depressive Disorder

NCT ID: NCT06958692

This clinical trial is studying the effectiveness and safety of a combination of two medications, dextromethorphan and bupropion, in treating adults with Major Depressive Disorder (MDD). The trial ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Beijing, Beijing, China

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