Clinical Trials for Malignant Neoplasm

Find clinical trials for malignant neoplasm. Discover research opportunities and treatment options in your area.

46 Active Trials Found

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A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)

NCT ID: NCT06941272

This clinical trial is studying a new treatment called HER3-DXd (also known as patritumab deruxtecan) for children with specific types of cancer: hepatoblastoma, a liver cancer commonly found in ba...

Recruiting

Phase: PHASE1 Type: interventional Locations: Iowa City, Iowa, United States, Seoul, , Korea, Republic Of +4 more

A Study of MK-4700 Alone or With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors (MK-4700-001)

NCT ID: NCT06894771

This clinical trial, called MK-4700-001, is studying a new medication called MK-4700, both on its own and in combination with another drug called pembrolizumab, in patients with advanced or metasta...

Recruiting

Phase: PHASE1 Type: interventional Locations: Haifa, , Israel, Petah Tiqva, , Israel +4 more

A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002)

NCT ID: NCT06818643

This clinical trial is studying a new treatment called MK-3120 for people with advanced solid tumors, which are cancers that have spread to other parts of the body and cannot be surgically removed....

Recruiting

Phase: PHASE1 Type: interventional Locations: Santiago., Region M. De Santiago, Chile, Santiago, Region M. De Santiago, Chile +14 more

Novel Outreach Methods to Increase Enrollment to Early Phase Clinical Trials

NCT ID: NCT05886764

This clinical trial is exploring new ways to encourage African American patients to participate in early-phase clinical trials for cancer treatments. The goal is to find out which outreach methods ...

Recruiting

Phase: NA Type: interventional Locations: Chicago, Illinois, United States

68Ga-FAPI PET/CT in Malignant Tumors

NCT ID: NCT05034146

This clinical trial is studying a new imaging technique called 68Ga-FAPI PET/CT to help doctors see and understand certain types of cancer better. The focus is on a special protein called fibroblas...

Recruiting

Phase: NA Type: interventional Locations: Wuhan, Hubei, China

DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

NCT ID: NCT06988475

The DETERMINE Trial is researching a medication called capmatinib, which is typically used to treat certain types of lung cancer. This study aims to see if capmatinib can also help adults with othe...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Southampton, , United Kingdom +14 more

Engagement of American Indians of Southwestern Tribal Nations in Cancer Genome Sequencing

NCT ID: NCT06207864

This clinical trial is focused on finding effective ways to engage and recruit American Indians from Southwestern Tribal Nations for a study on cancer genome sequencing. Researchers want to underst...

Recruiting

Phase: NA Type: interventional Locations: Albuquerque, New Mexico, United States

DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition

NCT ID: NCT05770102

The DETERMINE Trial Treatment Arm 02 is studying a drug called atezolizumab, which is already used to treat certain types of cancer in adults. This trial aims to see if atezolizumab can help patien...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Leeds, , United Kingdom +26 more

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers

NCT ID: NCT05770037

The DETERMINE Trial is studying a drug called alectinib, which is already used to treat certain types of lung cancer in adults. Researchers want to see if this medication can also help treat other ...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Leeds, , United Kingdom +26 more

DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-positive Cancers.

NCT ID: NCT05770544

The DETERMINE Trial is studying a medication called entrectinib to see if it can help treat various types of cancers that have a specific genetic change known as ROS1 gene fusion. While entrectinib...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Leeds, , United Kingdom +26 more

A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)

NCT ID: NCT06979596

This clinical trial, called MK-5684-015 or OMAHA-015, is studying a new medicine named MK-5684 to see if it can help treat certain types of cancer, specifically breast, ovarian, and endometrial can...

Not yet recruiting

Phase: PHASE2 Type: interventional

Intraoperative Tumor Margin Identification With ICG Dye Imaging

NCT ID: NCT04752137

This clinical trial is studying the use of a special dye called indocyanine green (ICG) to help surgeons identify and remove tumors more effectively during surgery. The main goal is to see if using...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States

Nasal Inhalation of Isopropyl Alcohol for the Treatment of Nausea in Patients With Cancer

NCT ID: NCT04181463

This clinical trial is studying whether inhaling isopropyl alcohol can help reduce nausea in cancer patients. Nausea can be a common and uncomfortable side effect of cancer and its treatments, and ...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant

NCT ID: NCT04453072

This clinical trial is exploring whether a special weight management app for iPhones, along with coaching, can help adolescents and young adults lose weight after they have undergone a stem cell tr...

Recruiting

Phase: NA Type: interventional Locations: Los Angeles, California, United States

Integrin αvβ6-targeted PET in Malignant Tumors

NCT ID: NCT05835570

This clinical trial is studying a new imaging technique for detecting malignant tumors, which are dangerous cancers that can grow and spread in the body. The researchers are testing a special imagi...

Recruiting

Type: observational Locations: Wuhan, Hubei, China

A Study of TSN1611 Treating Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

NCT ID: NCT06385925

This clinical trial is testing a new treatment called TSN1611 for patients with advanced solid tumors that have a specific genetic mutation known as KRAS G12D. This is the first time this treatment...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States, San Antonio, Texas, United States +4 more

Project: Every Child for Younger Patients With Cancer

NCT ID: NCT02402244

The clinical trial, titled "Project: Every Child for Younger Patients With Cancer," is focused on gathering important health information from young patients diagnosed with various types of cancer. ...

Recruiting

Type: observational Locations: New Haven, Connecticut, United States, Lebanon, New Hampshire, United States +256 more

Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases

NCT ID: NCT03741673

This clinical trial is looking at two different ways to use a treatment called stereotactic radiosurgery (SRS) for patients with brain metastases, which means cancer that has spread to the brain. T...

Recruiting

Phase: PHASE3 Type: interventional Locations: Houston, Texas, United States

Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers

NCT ID: NCT05823740

This clinical trial is focused on understanding how cancer treatment affects the body composition and physical function of children and young adults diagnosed with certain types of cancer, specific...

Recruiting

Phase: NA Type: interventional Locations: Chapel Hill, North Carolina, United States

NV-001 in the Treatment of Advanced Solid Tumors

NCT ID: NCT06051760

This clinical trial is studying a new treatment called NV-001, which is a type of vaccine designed to help the immune system fight advanced solid tumors, which are types of cancer that cannot be su...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, , China, Beijing, Beijing, China

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