Clinical Trials for Merkel Cell Carcinoma

Find clinical trials for merkel cell carcinoma. Discover research opportunities and treatment options in your area.

35 Active Trials Found

Showing 35 trials on this page

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Chemo-immunotherapy in Patients With Resectable Merkel Cell Carcinoma Prior to Surgery

NCT ID: NCT05594290

This clinical trial is studying a new treatment approach for patients with Merkel Cell Carcinoma (MCC), a rare type of skin cancer that can be surgically removed. The trial aims to see how effectiv...

Recruiting

Phase: PHASE2 Type: interventional Locations: Milan, , Italy

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

NCT ID: NCT05078047

This clinical trial is investigating whether a less frequent administration of immunotherapy (IO) can be just as effective as the standard treatment schedule for patients with certain types of adva...

Recruiting

Phase: PHASE3 Type: interventional Locations: Nice, , France, Rennes, , France +38 more

MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors

NCT ID: NCT05076760

This clinical trial is exploring a new treatment called MEM-288, which is an oncolytic virus, either by itself or combined with another medication called nivolumab, for patients with advanced solid...

Recruiting

Phase: PHASE1 Type: interventional Locations: Durham, North Carolina, United States, Tampa, Florida, United States

BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors

NCT ID: NCT05120271

This clinical trial is studying a new treatment called BOXR1030 T cells for patients with advanced solid tumors that have a specific protein called glypican-3 (GPC3) on their cancer cells. The tria...

Recruiting

Phase: PHASE1 Type: interventional Locations: London, , United Kingdom, London, , United Kingdom +6 more

Exercise to Boost Response to Checkpoint Blockade Immunotherapy

NCT ID: NCT06008977

This clinical trial is exploring whether exercising on the day of receiving immunotherapy can help improve the treatment response in patients with certain skin cancers, like melanoma, cutaneous squ...

Recruiting

Phase: NA Type: interventional Locations: Orlando, Florida, United States

Hypofractionated Radiation Therapy for Merkel Cell Carcinoma

NCT ID: NCT05100095

This clinical trial is studying a treatment called hypofractionated radiation therapy for patients with Merkel cell carcinoma (MCC), a rare and aggressive skin cancer. This new approach delivers hi...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Neoadjuvant Nivolumab and Relatlimab in Merkel Cell Carcinoma

NCT ID: NCT06151236

This clinical trial is studying a new treatment approach for Merkel cell carcinoma, a rare type of skin cancer. Researchers are testing a combination of two immunotherapy drugs, nivolumab and relat...

Recruiting

Phase: PHASE2 Type: interventional Locations: Wollstonecraft, New South Wales, Australia

Phase II Study of Peptide Receptor Radionuclide Therapy in Combination With Immunotherapy for Patients With Merkel Cell Cancer

NCT ID: NCT05583708

This clinical trial is looking at a new treatment approach for patients with Merkel cell carcinoma, a type of skin cancer. Researchers want to see how well a combination of two drugs, pembrolizumab...

Recruiting

Phase: PHASE2 Type: interventional Locations: Iowa City, Iowa, United States, Madison, Wisconsin, United States +1 more

A Beta-only IL-2 ImmunoTherapY Study

NCT ID: NCT05086692

This clinical trial, called the Beta-only IL-2 ImmunoTherapY Study, is looking to test a new treatment called MDNA11 for patients with advanced solid tumors, which are types of cancer that have spr...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Diego, California, United States, Baltimore, Maryland, United States +28 more

A Phase 1B/2 Study of RP1 in Solid Organ Transplant Patients With Advanced Cutaneous Malignancies

NCT ID: NCT04349436

This clinical trial is investigating a new treatment called RP1 for patients who have had solid organ transplants and are facing advanced skin cancers, such as cutaneous squamous cell carcinoma, Me...

Recruiting

Phase: PHASE1 Type: interventional Locations: Ann Arbor, Michigan, United States, New York, New York, United States +21 more

A Study of CRD3874-SI in People With Solid Tumors

NCT ID: NCT06021626

This clinical trial is studying a new drug called CRD3874-SI to see how safe it is for people with advanced cancers, specifically sarcoma and Merkel cell carcinoma. The researchers will start by te...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Middletown, New Jersey, United States +5 more

Electrochemotherapy (ECT) in Patients With Primary Visceral Tumors and/or Secondary Visceral Localizations, of Any Histotype

NCT ID: NCT06753136

This clinical trial is exploring a treatment called electrochemotherapy for patients with certain types of tumors in their organs, known as visceral tumors. These can include cancers like liver can...

Not yet recruiting

Phase: NA Type: interventional Locations: Padova, , Italy

Study of 225Ac-SS0110 in Subjects With ES-SCLC or MCC (SANTANA-225 )

NCT ID: NCT06939036

The SANTANA-225 trial is studying a new treatment called 225Ac-SS0110 for patients with advanced small cell lung cancer (ES-SCLC) or Merkel cell carcinoma (MCC), a type of skin cancer. The goal of ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Miami, Florida, United States

Study of Avelumab and/or Radiation Therapy in People With Advanced Merkel Cell Carcinoma

NCT ID: NCT04792073

This clinical trial is studying a combination of a medication called avelumab and a special type of radiation therapy known as comprehensive ablative radiation therapy (CART) for people with advanc...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Harrison, New York, United States +5 more

Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors

NCT ID: NCT04157985

This clinical trial is studying the best length of treatment with a type of cancer therapy called PD-1/PD-L1 inhibitors, which are used for various advanced solid tumors, including lung, bladder, a...

Recruiting

Phase: PHASE3 Type: interventional Locations: Pittsburgh, Pennsylvania, United States

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

NCT ID: NCT06814496

This clinical trial is investigating a new treatment approach for patients with certain types of cancer, including melanoma, thyroid cancer, and various other tumors. The main goal is to see if com...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Tucson, Arizona, United States

EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin Cancers

NCT ID: NCT06223659

This clinical trial is studying the effectiveness of EMLA topical cream in reducing pain for patients with skin cancers, such as melanoma and squamous cell carcinoma, who are receiving a special in...

Recruiting

Phase: PHASE2 Type: interventional Locations: Columbus, Ohio, United States

A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

NCT ID: NCT05864144

This clinical trial is studying a new treatment called SNS-101, which is an antibody designed to help the immune system fight against certain advanced solid tumors. It will be tested on its own and...

Recruiting

Phase: PHASE1 Type: interventional Locations: Pittsburgh, Pennsylvania, United States, Louisville, Kentucky, United States +9 more

Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus

NCT ID: NCT02479698

This clinical trial is exploring a new treatment option for patients with certain cancers and viral infections, specifically those caused by the BK and JC viruses. The study is looking at how effec...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Neoadjuvant PD-1 Blockade in Resectable Merkel Cell Carcinoma

NCT ID: NCT05496036

This clinical trial is studying a new treatment approach for patients with Merkel cell carcinoma (MCC), a rare type of skin cancer. The main goal is to see how well a drug called pembrolizumab work...

Recruiting

Phase: PHASE2 Type: interventional Locations: Philadelphia, Pennsylvania, United States

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