Clinical Trials for Metastatic Colorectal Carcinoma

Find clinical trials for metastatic colorectal carcinoma. Discover research opportunities and treatment options in your area.

20 Active Trials Found

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CBX-12 for the Treatment of Metastatic Chemotherapy-Refractory Microsatellite Stable Colorectal Cancer

NCT ID: NCT06730100

This clinical trial, called CBX-12, is investigating a new treatment for patients with advanced colorectal cancer that has not responded to standard chemotherapy. Specifically, it targets patients ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States, Pittsburgh, Pennsylvania, United States

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

NCT ID: NCT04704661

The DASH Trial is a clinical study exploring the safety and effectiveness of two anti-cancer drugs, DS-8201a and AZD6738, for patients with various types of advanced solid tumors that express the H...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States, Saint Louis, Missouri, United States +22 more

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

NCT ID: NCT05803382

This clinical trial is studying a new anti-cancer drug called ZEN003694, which is being tested alongside the usual chemotherapy drug capecitabine. The goal is to see if this combination can safely ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Saint Louis, Missouri, United States, Oklahoma City, Oklahoma, United States +22 more

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

NCT ID: NCT06626256

This clinical trial is studying a new treatment called STIL101 for injection, designed to help patients with certain types of advanced cancers, including pancreatic, colorectal, renal cell, cervica...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Duarte, California, United States

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

NCT ID: NCT06265285

This clinical trial is exploring whether giving a cancer treatment called nivolumab at home is just as safe and effective as receiving it in a clinic. By allowing patients to receive treatment in t...

Recruiting

Phase: PHASE2 Type: interventional Locations: Jacksonville, Florida, United States

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

NCT ID: NCT04693377

The CROME Trial is studying a new treatment approach for patients suffering from painful bone metastases, which occur when cancer spreads to the bones. The trial compares two methods: one combines ...

Recruiting

Phase: NA Type: interventional Locations: Houston, Texas, United States

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

NCT ID: NCT06147037

This clinical trial is studying a new treatment called [225Ac]-FPI-2068 for adults with certain advanced cancers, including metastatic colorectal cancer, head and neck cancer, non-small cell lung c...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chicago, Illinois, United States, Edmonton, Alberta, Canada +15 more

Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study

NCT ID: NCT04430725

The ALLUME Study is a clinical trial that aims to find out which treatment works better for patients with certain types of cancer that have spread to other areas of the body, specifically lung canc...

Recruiting

Type: observational Locations: Houston, Texas, United States

Predicting Response to Immune Checkpoint Inhibitors Across Solid Tumors Using a Live Tumor Diagnostic Platform

NCT ID: NCT06349642

This clinical trial is investigating how well a new diagnostic tool called Elephas can predict how tumors respond to different cancer treatments, particularly immune therapies. The goal is to colle...

Recruiting

Type: observational Locations: Jacksonville, Florida, United States

First-in-human Phase I Study to Evaluate Safety, Tolerability and Antineoplastic Activity of OATD-02 in Patients with Selected Advanced And/or Metastatic Solid Tumours

NCT ID: NCT05759923

This clinical trial is testing a new treatment called OATD-02, which is taken by mouth, to see if it is safe and effective for people with advanced cancers, such as advanced ovarian, renal, pancrea...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bydgoszcz, Kujawsko Pomorskie, Poland, Otwock, Mazowieckie, Poland +1 more

Intraperitoneal Oxaliplatin and Fluorouracil for the Treatment of Patients with Peritoneal Metastases from Colorectal Cancer

NCT ID: NCT06269978

This clinical trial is investigating a new way to treat patients with colorectal cancer that has spread to the lining of the abdomen, known as peritoneal metastasis. The study is testing the safety...

Recruiting

Phase: PHASE1 Type: interventional Locations: Columbus, Ohio, United States

SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial

NCT ID: NCT04599140

The STOPTRAFFIC-1 trial is a clinical study that is looking at a new treatment combination for patients with advanced colorectal cancer that cannot be removed by surgery. Specifically, it tests two...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

An Investigational Scan (Intravoxel Incoherent Motion Diffusion Weighted Imaging) for the Evaluation of Colorectal Cancer Liver Metastases Treatment Response

NCT ID: NCT04796818

This clinical trial is looking at a new type of imaging scan called intravoxel incoherent motion diffusion weighted imaging (IVIM DWI) to help doctors understand how well treatments are working for...

Recruiting

Phase: NA Type: interventional Locations: Houston, Texas, United States

Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

NCT ID: NCT04221893

This clinical trial is exploring how effective radiation therapy is for treating advanced gastrointestinal cancers that have spread to other parts of the body. The goal is to see if combining radia...

Recruiting

Phase: NA Type: interventional Locations: San Francisco, California, United States

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

NCT ID: NCT05863195

The PUMP Trial is looking at a new way to treat patients with advanced colorectal cancer that has spread to the liver and cannot be surgically removed. This study is comparing two approaches: one g...

Recruiting

Phase: PHASE3 Type: interventional Locations: Durham, North Carolina, United States, Cleveland, Ohio, United States +38 more

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

NCT ID: NCT04329494

This clinical trial is looking at a new way to give chemotherapy to patients with advanced cancers, such as ovarian, uterine, stomach (gastric), appendiceal, or colorectal cancer that has spread to...

Recruiting

Phase: PHASE1 Type: interventional Locations: Duarte, California, United States, Jacksonville, Florida, United States +1 more

Local Liver Treatment for Multi-organ Colorectal Cancer Metastases

NCT ID: NCT06449937

This clinical trial is looking at how well local treatments for liver tumors can work when combined with other treatments for colorectal cancer that has spread to multiple organs. The goal is to se...

Recruiting

Phase: NA Type: interventional Locations: Wuhu, Anhui, China, Hefei, Anhui, China +4 more

Clinical Study Evaluating the Anticancer Effect of Pentoxiphylline in Patients With Metastatic Colorectal Cancer

NCT ID: NCT06115174

This clinical trial is looking at the potential benefits of a drug called Pentoxiphylline for patients with metastatic colorectal cancer, which means the cancer has spread to other parts of the bod...

Not yet recruiting

Phase: PHASE4 Type: interventional

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

NCT ID: NCT05733000

This clinical trial is investigating a new treatment approach for patients with certain advanced cancers that have not responded to standard chemotherapy. The study is testing a combination of thre...

Recruiting

Phase: PHASE2 Type: interventional Locations: Chicago, Illinois, United States

BRAF Inhibitor Encorafenib And Cetuximab Real Life Investigation of Next Generation CRC Treatment

NCT ID: NCT04673955

The BERING CRC trial is investigating the effectiveness and safety of two medications, encorafenib and cetuximab, for patients with a specific type of metastatic colorectal cancer (mCRC) that has a...

Recruiting

Type: observational Locations: Berlin, , Germany, Wien, , Austria +71 more

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