Clinical Trials for Molecular Mechanisms of Pharmacological Action

Find clinical trials for molecular mechanisms of pharmacological action. Discover research opportunities and treatment options in your area.

6 Active Trials Found

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Natural History of Depression, Bipolar Disorder and Suicide Risk

NCT ID: NCT06462196

This clinical trial is studying mood disorders like depression and bipolar disorder, which are often hard to treat effectively. Researchers are looking to understand how these conditions affect pat...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

NCT ID: NCT06511908

This clinical trial is studying a new medication called (2R,6R)-hydroxynorketamine (HNK) to see if it can help people with major depressive disorder (MDD) who have not found relief from other treat...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

NCT ID: NCT05465031

The MAINSTREAM trial is studying whether a medication called sacubitril/valsartan can help prevent heart problems in women with breast cancer who are receiving specific chemotherapy treatments. Bre...

Recruiting

Phase: PHASE4 Type: interventional Locations: Opole, Opolskie, Poland, Gliwice, Silesia, Poland +3 more

Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and Melanoma

NCT ID: NCT04572451

This clinical trial is studying a new treatment approach for patients with advanced solid tumors, including melanoma, that cannot be surgically removed. The researchers are testing a combination of...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chicago, Illinois, United States, Pittsburgh, Pennsylvania, United States

Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB

NCT ID: NCT06535568

This clinical trial is studying the effects of two different types of antiplatelet therapy—single antiplatelet therapy (SAPT) versus dual antiplatelet therapy (DAPT)—in older patients or those at h...

Not yet recruiting

Phase: NA Type: interventional

Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

NCT ID: NCT04289142

This clinical trial is studying the effects of a medication called Dexmedetomidine (DEX) on the mental recovery of patients who undergo heart surgery. Researchers want to find out if DEX can help p...

Recruiting

Phase: PHASE4 Type: interventional Locations: Toronto, Ontario, Canada, Toronto, Ontario, Canada

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