Clinical Trials for Myelodysplastic Syndromes

Find clinical trials for myelodysplastic syndromes. Discover research opportunities and treatment options in your area.

158 Active Trials Found

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A First in Human Study of AUR 103 Calcium to Evaluate Safety, Pharmacokinetics and Pharmacodynamics

NCT ID: NCT05607199

This clinical trial, called AUR 103 Calcium, is the first study in humans to investigate the safety and effectiveness of a new treatment for patients with certain advanced cancers, including solid ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Pune, Maharashtra, India, Mysore, Karnataka, India +4 more

Upfront Related Donor Transplantation in Patients With Myelodisplatic Syndrome : a Phase 2 Trial

NCT ID: NCT06235398

This clinical trial is studying a new approach to treating patients with high-risk Myelodysplastic Syndromes (MDS) by looking at the benefits of starting a related donor stem cell transplant earlie...

Not yet recruiting

Phase: PHASE2 Type: interventional

Role of BMP Pathway in MDS Progression

NCT ID: NCT06175923

This clinical trial is investigating the role of a specific biological pathway called the Bone Morphogenetic Protein (BMP) pathway in the progression of myelodysplastic syndromes (MDS), which are b...

Not yet recruiting

Type: observational Locations: Lyon, , France

A Study of TQB3454 Tablets in Patients With Blood Tumors

NCT ID: NCT06218771

This clinical trial is looking at a new medication called TQB3454, which comes in tablet form, to see how safe it is for patients with specific blood cancers: acute myeloid leukemia and myelodyspla...

Recruiting

Phase: PHASE1 Type: interventional Locations: Wuxi, Jiangsu, China, Shanghai, Shanghai, China +15 more

A Study Using Subject-specific MRD to Adopt Treatment After HSCT for Subjects With MDS

NCT ID: NCT05788679

This clinical trial is looking at a new way to prevent relapse in patients with certain types of blood disorders, like Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML). Researchers ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Stockholm, , Sweden

Safety and Efficacy of Unrelated Umbilical Cord Blood Microtransplantation in Patients With Higher-risk MDS

NCT ID: NCT06109064

This clinical trial is studying a new treatment for patients with myelodysplastic syndromes (MDS), a group of disorders caused by poorly formed or dysfunctional blood cells. The researchers are loo...

Recruiting

Phase: PHASE2 Type: interventional Locations: Hefei, Anhui, China

Methods of T Cell Depletion Trial (MoTD)

NCT ID: NCT04888741

The Methods of T Cell Depletion Trial (MoTD) is a research study designed to improve the safety of stem cell transplants for patients with certain blood cancers, like acute myeloid leukemia and mul...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Nottingham, , United Kingdom +13 more

A Single-arm Trial of Roxadustat Combined With Retinoic Acid in the Treatment of Refractory Low-risk MDS

NCT ID: NCT06020833

This clinical trial is studying a new treatment approach for patients with a type of blood disorder called low-risk myelodysplastic syndromes (MDS) that has not responded to previous treatments. Th...

Not yet recruiting

Phase: PHASE1 Type: interventional

Study of BC3402 in Combination With Azacitidine in Patients With MDS and CMML

NCT ID: NCT05970822

This clinical trial is studying a new treatment called BC3402 when combined with azacitidine (AZA) for patients with specific blood disorders known as Myelodysplastic Syndromes (MDS) and Chronic My...

Recruiting

Phase: PHASE1 Type: interventional Locations: Tianjin, Tianjin, China

Venetoclax in Combination With Non-myeloablative Conditioning Allogeneic Haematopoietic Stem Cell Transplantation

NCT ID: NCT05005299

This clinical trial is studying the safety and effectiveness of a medication called venetoclax when used with a specific type of treatment, known as non-myeloablative conditioning, before patients ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Melbourne, Victoria, Australia

Faecal Microbiota Transplantation After Allogeneic Stem Cell Transplantation

NCT ID: NCT04935684

This clinical trial is exploring a treatment called Fecal Microbiota Transplantation (FMT) to help prevent complications in patients who have received a special type of blood stem cell transplant, ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Amiens, , France, Angers, , France +18 more

Unrelated Umbilical Cord Blood Stem Cell Combined With Azacitidine Based Treatment for Advanced MDS,CMML-2 and sAML

NCT ID: NCT05584761

This clinical trial is looking at a new treatment approach for patients with advanced blood disorders, specifically myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia (CMML-2), and se...

Recruiting

Phase: PHASE1 Type: interventional Locations: Nanjing, Jiangsu, China

Allogeneic Hematopoietic Cell Transplantation From HLA-matched Donor After Flu-Mel-PTCy Versus Flu-Mel-ATG Reduced-intensity Conditioning

NCT ID: NCT03852407

This clinical trial is comparing two different ways to prepare patients for an allogeneic hematopoietic cell transplant, which is a type of treatment for several blood cancers, including acute myel...

Recruiting

Phase: PHASE2 Type: interventional Locations: Gent, , Belgium, Leuven, , Belgium +10 more

Lifestyle-modifying Interventions in Low-risk MDS Patients

NCT ID: NCT05433805

This clinical trial is looking at how lifestyle changes, like exercise and a special diet, can help patients with low-risk myelodysplastic syndromes (MDS), a type of blood disorder. Doctors believe...

Not yet recruiting

Phase: NA Type: interventional

Hypomemylating Agents Combination With eDC Therapy for Elderly Patients With Myelodysplastic Syndrome

NCT ID: NCT04999943

This clinical trial is investigating a new treatment approach for elderly patients with a condition called myelodysplastic syndrome (MDS), which affects how blood cells are made. The study is testi...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, , China

Could Ki-67 be Used as a Diagnostic or Prognostic Marker in Hemato-oncological Diagnostics?

NCT ID: NCT04517175

This clinical trial is studying a marker called Ki-67, which helps doctors understand how quickly cancer cells are growing. While Ki-67 is commonly used in solid tumors, its use in blood cancers (l...

Not yet recruiting

Type: observational

Institut Paoli Calmettes Myelodysplastic Syndromes Database

NCT ID: NCT03275480

The Institut Paoli Calmettes Myelodysplastic Syndromes Database is a clinical trial that aims to collect information about patients who have been diagnosed with Myelodysplastic Syndromes (MDS). MDS...

Recruiting

Type: observational Locations: Marseille, , France

A Study of LB-100 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS)

NCT ID: NCT03886662

This clinical trial is studying a new drug called LB-100 to see if it is safe and effective for patients with low or intermediate risk myelodysplastic syndromes (MDS), which are conditions that aff...

Recruiting

Phase: PHASE1 Type: interventional Locations: Tampa, Florida, United States

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