Clinical Trials for Myelodysplastic Syndromes

PK/Efficacy Bridging Study of ASTX727 in Chinese Subjects with Myelodysplastic Syndromes

NCT ID: NCT06091267

This clinical trial is studying a new treatment called ASTX727 for patients with a condition known as Myelodysplastic Syndromes (MDS), which affects how your blood cells are made. The trial will co...

Ferroptosis Study in SF3B1-mutant Myelodysplastic Syndromes (FerMDS)

NCT ID: NCT05924074

The Ferroptosis Study in SF3B1-mutant Myelodysplastic Syndromes (FerMDS) is looking into a specific type of cell death called ferroptosis and how it might be affecting patients with myelodysplastic...

Phase I Trial for Patients w/ Advanced Hematologic Malignancies Undergoing Allogeneic HCT

NCT ID: NCT06551584

This clinical trial is looking at a new treatment approach for patients with advanced blood cancers, such as acute myeloid leukemia and myelodysplastic syndromes. The main goal is to assess the saf...

Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in MDS

NCT ID: NCT05434598

This clinical trial is looking at a new testing method called ChromoSeq to see if it can help doctors better understand and treat patients with myelodysplastic syndromes (MDS), a group of diseases ...

A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

NCT ID: NCT03802695

This clinical trial is studying a new treatment called Orca-Q, which involves using specially engineered donor cells to help patients with certain blood cancers, such as acute myeloid leukemia and ...

A Study to Evaluate the MNV-201 in Patients with Low Risk MDS

NCT ID: NCT06465160

This clinical trial is studying a new treatment called MNV-201 for patients with low-risk myelodysplastic syndromes (MDS), a condition that affects how the bone marrow produces blood cells. MNV-201...

Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders

NCT ID: NCT03579875

This clinical trial is studying a new treatment for patients with inherited bone marrow failure disorders, such as Fanconi Anemia and Severe Aplastic Anemia. The goal of the trial is to see if a sp...

A Study of GLB-001 in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher Risk Myelodysplastic Syndromes

NCT ID: NCT06146257

This clinical trial is studying a new medication called GLB-001 for patients with relapsed or refractory acute myeloid leukemia (AML) and higher-risk myelodysplastic syndromes (MDS). The trial aims...

A Study of GLB-001 in Patients With Myeloid Malignancies

NCT ID: NCT06378437

This clinical trial, called GLB-001-02, is investigating a new treatment called GLB-001 for patients with certain blood cancers known as myeloid malignancies. These include conditions like polycyth...

Natural Killer (NK) Cells in Combination with Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer

NCT ID: NCT05400122

This clinical trial is studying a new treatment approach for certain cancers, including colorectal cancer and various blood cancers. Researchers are investigating whether combining special immune c...

CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCT

NCT ID: NCT03810196

This clinical trial is studying a new treatment approach for patients, particularly children and young adults under 25 years old, who have certain types of blood cancers like leukemia and lymphoma ...

PTCy and ATG for MSD and MUD Transplants

NCT ID: NCT06299462

This clinical trial is studying a new way to prevent a serious complication called graft-versus-host disease (GVHD) in patients receiving stem cell transplants for certain blood cancers, like acute...

Monitoring Mutational Burden in Low Risk MDS Patients Using Sequential Peripheral Blood Samples

NCT ID: NCT04251078

This clinical trial is studying a new way to monitor patients with low-risk myelodysplastic syndromes (MDS), which are conditions where the bone marrow doesn't produce enough healthy blood cells. T...

Randomized Study of Conditioning of Fludarabine Combined With Single or Dual Alkylating Agents in Myeloid Malignancies

NCT ID: NCT05991908

This clinical trial is looking at different treatments for adults with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS) who are preparing for a type of stem cell transplant called al...

HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AML

NCT ID: NCT06594445

This clinical trial, titled HM2023-05, is studying a new treatment called GTB-3650 for adults aged 18 and older who have certain types of blood cancer, specifically Acute Myeloid Leukemia (AML) or ...

Iadademstat With Hypomethylating Agent in Patients With Myelodysplastic Syndrome

NCT ID: NCT06502145

This clinical trial is studying a new treatment combination for adults diagnosed with myelodysplastic syndromes (MDS), a group of conditions that affect blood cell production. The goal is to find t...

Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care

NCT ID: NCT05745285

This clinical trial is studying how the services and programs offered by the Leukemia and Lymphoma Society (LLS) affect patients with blood cancers like leukemia, lymphoma, and myeloma. The goal is...

Biocollection in MyeloDysplastic Syndrome (P-MDS)

NCT ID: NCT04869683

This clinical trial, called the Biocollection in MyeloDysplastic Syndrome (P-MDS), is studying a group of blood disorders known as myelodysplastic syndromes (MDS). MDS affects how the body produces...

HEME Home Transfusion Program

NCT ID: NCT06487247

The HEME Home Transfusion Program is a research study designed to explore a new way of providing blood transfusions to patients with certain blood cancers, like leukemia and lymphoma, in the comfor...

Pathogenesis of Hematologic Malignancies

NCT ID: NCT01728402