Clinical Trials for Myelodysplastic/Myeloproliferative Neoplasm

Find clinical trials for myelodysplastic/myeloproliferative neoplasm. Discover research opportunities and treatment options in your area.

13 Active Trials Found

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A Study of BGB-11417 in Participants With Myeloid Malignancies

NCT ID: NCT04771130

This clinical trial is studying a new drug called BGB-11417 to see how safe it is, how well it works, and what the best dose is for treating certain blood cancers, specifically Acute Myeloid Leukem...

Recruiting

Phase: PHASE1 Type: interventional Locations: Milwaukee, Wisconsin, United States, Duarte, California, United States +103 more

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

NCT ID: NCT06661915

This clinical trial is investigating a new treatment for advanced blood disorders known as myeloproliferative neoplasms (MPNs). Specifically, the study is comparing the effects of a medication call...

Recruiting

Phase: PHASE2 Type: interventional Locations: Oklahoma City, Oklahoma, United States, Chicago, Illinois, United States +4 more

A Telehealth Advance Care Planning Intervention

NCT ID: NCT05875805

This clinical trial is exploring how a telehealth program can help older patients with certain blood cancers, such as acute myeloid leukemia and myelodysplastic syndromes, communicate better about ...

Recruiting

Phase: NA Type: interventional Locations: Rochester, New York, United States

Axatilimab With or Without Azacitidine for the Treatment of Patients With Advanced Phase Myeloproliferative Neoplasms, Myeloproliferative Neoplasm/Myelodysplastic Syndrome Overlap or High Risk Chronic Myelomonocytic Leukemia

NCT ID: NCT06523556

This clinical trial is looking at a new treatment option for patients with certain serious blood cancers, including advanced phase myeloproliferative neoplasms (MPN), which are conditions where the...

Recruiting

Phase: PHASE1 Type: interventional Locations: Columbus, Ohio, United States

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

NCT ID: NCT05600894

This clinical trial is studying the effectiveness of a combination of two medications, decitabine and cedazuridine (called ASTX727), along with venetoclax, for treating specific types of blood canc...

Recruiting

Phase: PHASE2 Type: interventional Locations: Chicago, Illinois, United States, New Haven, Connecticut, United States +34 more

Phase I/II Study of Tagraxofusp in Combination With Decitabine for Patients With Myelomonocytic/Myeloproliferative Neoplasm and High Risk Myelodysplastic Syndromes

NCT ID: NCT05038592

This clinical trial is investigating a new treatment for a type of blood cancer called Chronic Myelomonocytic Leukemia (CMML). The treatment combines two medications: tagraxofusp, which targets and...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy

NCT ID: NCT03630991

This clinical trial is studying two potential treatments, edetate calcium disodium and succimer, for patients with certain types of blood cancers, specifically acute myeloid leukemia (AML) or myelo...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Personalized NK Cell Therapy in CBT

NCT ID: NCT02727803

This clinical trial is looking at a new treatment called personalized natural killer (NK) cell therapy for patients with certain types of blood cancers, including leukemia, lymphoma, and myelodyspl...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant

NCT ID: NCT03964506

This clinical trial is studying the safety and effects of hyperbaric oxygen therapy for patients undergoing stem cell transplantation. The goal is to see if this therapy can help improve the recove...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Rochester, New York, United States

Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms

NCT ID: NCT04282187

This clinical trial is exploring the effectiveness of a combination treatment using decitabine and other medications—ruxolitinib, fedratinib, or pacritinib—for patients with advanced myeloprolifera...

Recruiting

Phase: PHASE2 Type: interventional Locations: Seattle, Washington, United States

Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK [IMGN632]) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms

NCT ID: NCT06034470

This clinical trial is studying a new treatment approach for adults with newly diagnosed acute myeloid leukemia (AML) and other serious blood disorders. The treatment combines a specific chemothera...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

NCT ID: NCT04771572

This clinical trial is investigating a new oral medication called LP-118 for patients with certain types of advanced blood cancers, including Chronic Lymphocytic Leukemia (CLL), Non-Hodgkin Lymphom...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chicago, Illinois, United States, Boston, Massachusetts, United States +8 more

Acquired Pyruvate Kinase Deficiency In Clonal Myeloid Neoplasms

NCT ID: NCT04902833

The clinical trial titled "Acquired Pyruvate Kinase Deficiency In Clonal Myeloid Neoplasms" is investigating a specific type of blood condition known as pyruvate kinase deficiency, which can lead t...

Recruiting

Type: observational Locations: Boston, Massachusetts, United States

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