Clinical Trials for Neoplasms by Histologic Type

Find clinical trials for neoplasms by histologic type. Discover research opportunities and treatment options in your area.

17 Active Trials Found

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A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma

NCT ID: NCT07075185

This clinical trial is testing a new gene therapy called KLN-001 for people with multiple myeloma, a type of blood cancer that has come back or has not responded to previous treatments. The main go...

Recruiting

Phase: PHASE1 Type: interventional Locations: Melbourne, Victoria, Australia, Camperdown, New South Wales, Australia +1 more

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT ID: NCT06001788

This clinical trial is studying a new treatment called ziftomenib, which is being tested in combination with standard therapies for patients with relapsed or refractory acute myeloid leukemia (AML)...

Recruiting

Phase: PHASE1 Type: interventional Locations: Burlington, Vermont, United States, New York, New York, United States +41 more

Bevacizumab in Adults With Recurrent Respiratory Papillomatosis (RRP)

NCT ID: NCT05797246

This clinical trial is studying a medication called bevacizumab to see if it can help reduce the number of surgeries needed for adults with recurrent respiratory papillomatosis (RRP), a rare condit...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

NCT ID: NCT06988475

The DETERMINE Trial is researching a medication called capmatinib, which is typically used to treat certain types of lung cancer. This study aims to see if capmatinib can also help adults with othe...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Southampton, , United Kingdom +14 more

DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition

NCT ID: NCT05770102

The DETERMINE Trial Treatment Arm 02 is studying a drug called atezolizumab, which is already used to treat certain types of cancer in adults. This trial aims to see if atezolizumab can help patien...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Leeds, , United Kingdom +26 more

DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-positive Cancers.

NCT ID: NCT05770544

The DETERMINE Trial is studying a medication called entrectinib to see if it can help treat various types of cancers that have a specific genetic change known as ROS1 gene fusion. While entrectinib...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Leeds, , United Kingdom +26 more

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers

NCT ID: NCT05770037

The DETERMINE Trial is studying a drug called alectinib, which is already used to treat certain types of lung cancer in adults. Researchers want to see if this medication can also help treat other ...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Leeds, , United Kingdom +26 more

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

NCT ID: NCT03911388

This clinical trial is studying a new treatment called G207, which is an experimental virus therapy designed to target certain types of brain tumors in children and young adults. Specifically, it f...

Recruiting

Phase: PHASE1 Type: interventional Locations: Saint Louis, Missouri, United States, Houston, Texas, United States +1 more

Study of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHL

NCT ID: NCT02690545

This clinical trial is studying a new treatment for patients with certain types of lymphoma, specifically those whose cancer has come back or has not responded to previous treatments. The treatment...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chapel Hill, North Carolina, United States

Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and Melanoma

NCT ID: NCT04572451

This clinical trial is studying a new treatment approach for patients with advanced solid tumors, including melanoma, that cannot be surgically removed. The researchers are testing a combination of...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chicago, Illinois, United States, Pittsburgh, Pennsylvania, United States

A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study

NCT ID: NCT06271252

The RIGEL Study is a clinical trial designed to test a new treatment called OriCAR-017 for patients with relapsed or refractory multiple myeloma, which is a type of blood cancer. This is the first ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Atlanta, Georgia, United States

Phase I Study of KY-0118 in Subjects With Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT06175780

This clinical trial is studying a new treatment called KY-0118 for patients with locally advanced or metastatic solid tumors, which are types of cancer that have either spread from their original s...

Recruiting

Phase: PHASE1 Type: interventional Locations: Tianjin, Tianjin, China, Hangzhou, Zhejiang, China +7 more

Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture

NCT ID: NCT05440240

This clinical trial is studying a treatment for Dupuytren's contracture, a condition that causes the fingers to bend toward the palm due to thickened tissue. Researchers want to compare two approac...

Recruiting

Phase: PHASE4 Type: interventional Locations: Silkeborg, , Denmark

Spanish Series of Patients Treated With the Radionuclide Lutetium177

NCT ID: NCT04949282

This clinical trial is studying the use of a treatment called Lutetium-177-DOTATATE, which is used for patients with certain types of tumors, including neuroendocrine tumors and other related cance...

Recruiting

Type: observational Locations: Madrid, , Spain, Madrid, , Spain +19 more

Anlotinib Hydrochloride Capsules Combined With TQB2450 Injection in Esophageal Squamous Cell Carcinoma Patients

NCT ID: NCT05252078

This clinical trial is investigating the effects of two medications, Anlotinib Hydrochloride Capsules and TQB2450 Injection, in patients with esophageal squamous cell carcinoma (ESCC) who have rece...

Recruiting

Phase: PHASE2 Type: interventional Locations: Nanchang, Jiangxi, China

A Phase 2 Study of Isatuximab in Combination With Pomalidomide and Dexamethasone in MM Patients Who Received One Prior Line of Therapy Containing Lenalidomide and a Proteasome Inhibitor

NCT ID: NCT05298683

This clinical trial is testing a new combination of treatments for patients with multiple myeloma, a type of blood cancer. The study will look at how well isatuximab, pomalidomide, and low-dose dex...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Ioannina, , Greece, Athens, , Greece +4 more

Penpulimab Plus R2-GemOx Regimen in Relapsed or Refractory DLBCL

NCT ID: NCT05186558

This clinical trial is testing a new treatment approach for patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL), a type of blood cancer. The study will give participants a co...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Hefei, Anhui, China, Changzhou, Jiangsu, China +2 more

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