Clinical Trials for Neurofibromatosis Type 1

Find clinical trials for neurofibromatosis type 1. Discover research opportunities and treatment options in your area.

11 Active Trials Found

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A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)

NCT ID: NCT06507748

This clinical trial is studying a new way to measure pain and other unusual sensations in people with Neurofibromatosis Type 1 (NF1), a genetic condition that can cause tumors to grow along nerves ...

Not yet recruiting

Phase: NA Type: interventional Locations: Bethesda, Maryland, United States

A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

NCT ID: NCT03871257

This clinical trial is looking at a new drug called selumetinib to see if it works as well or better than the standard treatments, carboplatin and vincristine, for children and young adults with lo...

Recruiting

Phase: PHASE3 Type: interventional Locations: New Haven, Connecticut, United States, Lebanon, New Hampshire, United States +138 more

A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

NCT ID: NCT06541847

This clinical trial is studying a new treatment called HLX-1502 for patients with Neurofibromatosis Type 1 (NF1), a genetic condition that can cause tumors on nerves. The trial is open to adults ag...

Recruiting

Phase: PHASE2 Type: interventional Locations: Birmingham, Alabama, United States, Chicago, Illinois, United States +6 more

PASS of Paediatric Patients Initiating Selumetinib

NCT ID: NCT05388370

The PASS of Paediatric Patients Initiating Selumetinib trial is studying the safety of a medication called selumetinib in children and teenagers with Neurofibromatosis Type 1 (NF1), particularly th...

Recruiting

Type: observational Locations: Paris, , France, Torino, , Italy +51 more

Development of Patient-Reported Outcome Measures Assessing Tumor-Related Disfigurement and Appearance Concerns in Neurofibromatosis Type 1

NCT ID: NCT06880991

This clinical trial is studying how two questionnaires can help understand how people with Neurofibromatosis Type 1 (NF1) feel about the appearance of tumors that grow on their nerves. These tumors...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

Familial Investigations of Childhood Cancer Predisposition

NCT ID: NCT03050268

This clinical trial, called "Familial Investigations of Childhood Cancer Predisposition," is studying how certain genetic factors may increase the risk of developing specific types of childhood can...

Recruiting

Type: observational Locations: Memphis, Tennessee, United States

Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1 Using Novel Magnetic Resonance Imaging Techniques Paired With Artificial Intelligence

NCT ID: NCT04763109

This clinical trial is looking at a new way to identify early signs of cancer in children with a condition called Neurofibromatosis Type 1 (NF-1). The researchers are using special whole-body MRI s...

Recruiting

Phase: NA Type: interventional Locations: Los Angeles, California, United States

FARD (RaDiCo Cohort) (RaDiCo-FARD)

NCT ID: NCT05954416

The RaDiCo-FARD trial is studying the impact of nine rare skin diseases on patients and their families. These conditions include Inherited Epidermolysis Bullosa, Ichthyosis, and Neurofibromatosis T...

Recruiting

Type: observational Locations: Rouen, , France, Paris, , France +13 more

Neurofibromatosis Type 1 Tumor Early Detection Study

NCT ID: NCT06515860

The Neurofibromatosis Type 1 Tumor Early Detection Study is looking at whether a simple blood test, called a liquid biopsy, can help detect a serious tumor called malignant peripheral nerve sheath ...

Recruiting

Type: observational Locations: Boston, Massachusetts, United States

Developing Biomarkers of Plexiform Tumor Burden in Patients With Neurofibromatosis-Type 1

NCT ID: NCT05238909

This clinical trial is focused on studying a condition called Neurofibromatosis type 1 (NF1), which can lead to the development of tumors, specifically a type known as plexiform neurofibromas. The ...

Recruiting

Type: observational Locations: Chicago, Illinois, United States

Reliability of Functional Outcome Measures in Neurofibromatosis 1: Test- Retest

NCT ID: NCT05186870

This clinical trial is looking at how reliable certain physical tests are for adults with Neurofibromatosis Type 1 (NF1). Specifically, it will assess whether repeated tests of walking, getting up ...

Recruiting

Type: observational Locations: London, , United Kingdom, London, , United Kingdom

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