Clinical Trials for Osteosarcoma

Find clinical trials for osteosarcoma. Discover research opportunities and treatment options in your area.

68 Active Trials Found

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Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

NCT ID: NCT06625190

This clinical trial is investigating a new treatment approach for certain solid tumors in young patients, including conditions like neuroblastoma and rhabdomyosarcoma. The treatment involves using ...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Gainesville, Florida, United States

Upfront Surgical Resection for Osteosarcoma

NCT ID: NCT06384404

This clinical trial is studying a treatment approach for patients with a type of bone cancer called osteosarcoma, specifically when it occurs in the arms or legs. The main goal is to find out if re...

Type: observational Locations: Bronx, New York, United States

Losartan + Sunitinib in Treatment of Osteosarcoma

NCT ID: NCT03900793

This clinical trial is studying a combination of two medications, Losartan and Sunitinib, to find the highest safe dose that can be given to patients with osteosarcoma, a type of bone cancer. The t...

Phase: PHASE1 Type: interventional Locations: Los Angeles, California, United States, Aurora, Colorado, United States +2 more

Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas

NCT ID: NCT06709495

This clinical trial is studying a new drug called PEEL-224, which is being tested alongside two existing medications, Vincristine and Temozolomide. The goal is to see how well this combination work...

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States +3 more

Precision Therapy Based on Immune Microenvironment by Transcriptome Sequencing of Osteosarcoma, a Prospective, Multi-cohort Exploratory Clinical Study

NCT ID: NCT06776198

This clinical trial is exploring a new way to treat osteosarcoma, a type of bone cancer, by looking closely at the tumor's environment and its genetic makeup. Researchers have discovered different ...

Not yet recruiting

Type: observational

B7-H3 NIR Imaging for Osteosarcoma Surgery

NCT ID: NCT06778603

This clinical trial is studying a new imaging technique using a special probe called B7-H3-IRDye800CW to help surgeons remove all of the osteosarcoma (a type of bone cancer) during surgery. The goa...

Phase: PHASE1 Type: interventional Locations: Beijing, Beijing, China

A Phase 2 Pilot Study to Evaluate the Safety and the Anti-Tumour Activity of the Myc Inhibitor OMO-103 Administered Intravenously in Patients With Advanced High-Grade Osteosarcoma

NCT ID: NCT06650514

This clinical trial is testing a new treatment called OMO-103 for patients with advanced high-grade osteosarcoma, a type of bone cancer that can be challenging to treat. The study aims to see how s...

Phase: PHASE2 Type: interventional Locations: Barcelona, , Spain

START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer

NCT ID: NCT05492682

The START clinical trial is studying a new treatment called PeptiCRAd-1, which is combined with a type of therapy known as checkpoint inhibitors (CPIs) to see how well it works against certain canc...

Phase: PHASE1 Type: interventional Locations: Frankfurt, , Germany, Frankfurt, , Germany +2 more

Quantitative Margin Assessment Using High-resolution Positron Emission Tomography - Computed Tomograhy

NCT ID: NCT06726512

This clinical trial is looking at a new type of medical imaging called high-resolution mobile PET-CT scanning. The goal is to see how well this technology can help doctors check the edges of tumors...

Not yet recruiting

Phase: NA Type: interventional Locations: Groningen, , Netherlands

Trilaciclib Combing Chemotherapy in the Neoadjuvant Treatment of Osteosarcoma

NCT ID: NCT06714383

This clinical trial is studying a new treatment approach for patients with classic osteosarcoma, a type of bone cancer. The trial is testing a medication called Trilaciclib, which is used to help p...

Phase: PHASE2 Type: interventional Locations: Beijing, Beijing, China

ARTEMIS-103: Phase 1b Study of HS-20093 Combinations in Patients with Bone and Soft Tissue Sarcoma.

NCT ID: NCT06699576

The ARTEMIS-103 clinical trial is a research study aimed at testing a new treatment called HS-20093 for patients with advanced bone and soft tissue sarcomas, including osteosarcoma. HS-20093 is a s...

Not yet recruiting

Phase: PHASE1 Type: interventional

HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

NCT ID: NCT04995003

This clinical trial is exploring a new treatment for patients with advanced sarcoma, a type of cancer that can occur in various parts of the body. The study is testing a special type of immune cell...

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors

NCT ID: NCT02508038

This clinical trial is looking at a new way to treat children with certain types of blood cancers (like leukemia and lymphoma) and high-risk solid tumors (like neuroblastoma and osteosarcoma). The ...

Phase: PHASE1 Type: interventional Locations: Madison, Wisconsin, United States

AOH1996 for the Treatment of Refractory Solid Tumors

NCT ID: NCT05227326

This clinical trial is studying a new treatment called AOH1996 for patients with certain types of solid tumors that have not responded to standard treatments. Solid tumors include cancers like oste...

Phase: PHASE1 Type: interventional Locations: Duarte, California, United States, Scottsdale, Arizona, United States +1 more

Biology of Osteosarcoma (BOOST) Registry and Biobank

NCT ID: NCT03225872

The BOOST Registry and Biobank is a clinical trial focused on understanding osteosarcoma, a rare type of bone cancer. The goal of this study is to give every patient diagnosed with osteosarcoma the...

Type: observational Locations: Minneapolis, Minnesota, United States

Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton Therapy

NCT ID: NCT06029218

This clinical trial is exploring the effects of a new way to deliver proton therapy for certain types of cancers, including chordoma, chondrosarcoma, Ewing sarcoma, and osteosarcoma. Specifically, ...

Phase: NA Type: interventional Locations: Nice, , France

Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas Patients

NCT ID: NCT04698785

This clinical trial is studying the use of a medication called regorafenib combined with best supportive care (which focuses on helping patients feel better) as a maintenance treatment for patients...

Phase: PHASE2 Type: interventional Locations: Bordeaux, , France, Lyon, , France +15 more

Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas

NCT ID: NCT04055220

This clinical trial is investigating whether a medication called regorafenib can help prevent the return of bone sarcomas in patients who have already completed their first treatment. Bone sarcomas...

Phase: NA Type: interventional Locations: Lille, , France, Villejuif, , France +15 more

An Observational Study of Local Relapse After High Grade Osteosarcoma

NCT ID: NCT06017518

This clinical trial is looking at patients who have had high-grade osteosarcoma, a type of bone cancer, and have experienced a local relapse, which means the cancer has come back in the same area a...

Type: observational Locations: Pisa, Pi, Italy, Bologna, Bo, Italy

ARTEMIS-002: HS-20093 in Patients With Relapsed or Refractory Osteosarcoma and Other Sarcomas

NCT ID: NCT05830123

The ARTEMIS-002 clinical trial is studying a new treatment called HS-20093 for patients with osteosarcoma and other types of sarcomas that have not responded to previous therapies. HS-20093 is a sp...

Phase: PHASE2 Type: interventional Locations: Beijing, , China, Guangzhou, , China +14 more

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