A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

NCT ID: NCT06999187

This clinical trial is looking at a new treatment called DR-0202 for patients with certain types of advanced cancers, including triple-negative breast cancer and non-small cell lung cancer, among o...

Recruiting

Phase: PHASE1 Type: interventional Locations: Fairfax, Virginia, United States, Denver, Colorado, United States +8 more

Non-interventional Study to Collect Real-world Clinical and Patient-reported Outcomes in Ovarian Cancer

NCT ID: NCT04830709

This clinical trial is looking at how well the initial treatment for advanced ovarian cancer works in real-life situations. It focuses on women who have just been diagnosed with high-grade epitheli...

Recruiting

Type: observational Locations: Dresden, , Germany, Osnabrück, , Germany +113 more

Proactive Hemodynamic Management During Cytoreductive Surgery and HIPEC

NCT ID: NCT07070973

This clinical trial is studying a new way to carefully manage blood pressure and heart function during a major surgery called cytoreductive surgery with HIPEC, which is used to treat ovarian cancer...

Not yet recruiting

Phase: NA Type: interventional

DT2216 + Paclitaxel in Platinum-Resistant Ovarian Cancer

NCT ID: NCT06964009

This clinical trial is looking at a new treatment for women with recurrent ovarian cancer that has not responded to platinum-based chemotherapy. The study is testing a combination of two drugs: DT2...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC

NCT ID: NCT06303505

This clinical trial, called the NAPISTAR 1-01 study, is exploring a new treatment called TUB-040 for patients with ovarian cancer or non-small cell lung cancer (NSCLC). TUB-040 is designed to deliv...

Recruiting

Phase: PHASE1 Type: interventional Locations: Cincinnati, Ohio, United States, London, , United Kingdom +14 more

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

NCT ID: NCT06276491

This clinical trial is testing a new drug called XmAb541 to see if it is safe and well tolerated for patients with advanced solid tumors, particularly types like ovarian cancer, endometrial cancer,...

Recruiting

Phase: PHASE1 Type: interventional Locations: Columbus, Ohio, United States, Charlottesville, Virginia, United States +8 more

A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors

NCT ID: NCT06257264

This clinical trial is studying a new treatment called BG-68501 for patients with advanced-stage tumors, including certain types of breast cancer, lung cancer, ovarian cancer, and others. The main ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Saint Louis, Missouri, United States, Brisbane, Queensland, Australia +44 more

A Study of Second Look Laparoscopy (SLL) in People With Ovarian Cancer Who Have Completed Their First Course of Chemotherapy

NCT ID: NCT06240598

This clinical trial is studying the effects of a procedure called second look laparoscopy (SLL) in women with advanced ovarian cancer who have finished their first round of chemotherapy. The resear...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Boston, Massachusetts, United States +7 more

Contribution of Preserving the Superior Left Colic Artery to the Vascularization of the Descending Colon Prior to Colorectal Anastomosis During Left-Sided or Rectal Resections for Colorectal or Ovarian Cancer. (Revascularisation Colique)

NCT ID: NCT07098182

This clinical trial is looking at whether preserving a specific artery called the left colic artery during surgery can improve blood flow to the descending colon before reconnecting the bowel in pa...

Not yet recruiting

Phase: NA Type: interventional

A Phase 1 Study of [225Ac]-FPI-1434 Injection

NCT ID: NCT03746431

This clinical trial is studying a new treatment called [225Ac]-FPI-1434 Injection for patients with advanced solid tumors, including types like endometrial, cervical, ovarian, and breast cancers. T...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Adelaide, South Australia, Australia +15 more

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT ID: NCT04585750

The PYNNACLE clinical trial is studying a new treatment called PC14586, aimed at patients with advanced solid tumors that have a specific genetic mutation known as TP53 Y220C. This trial is current...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Charleston, South Carolina, United States +95 more

Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

NCT ID: NCT06819007

This clinical trial is testing a new treatment approach for women with advanced ovarian cancer that has a specific protein called HER2. The study is comparing two treatment options: a combination o...

Recruiting

Phase: PHASE3 Type: interventional Locations: Boston, Massachusetts, United States, Indianapolis, Indiana, United States +33 more

A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer

NCT ID: NCT06888921

This clinical trial is studying a new treatment called COM701 to see if it can help women with relapsed platinum-sensitive ovarian cancer. The main goal is to find out if COM701 can slow down the p...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Chicago, Illinois, United States +3 more

Relacorilant in Combination With Nab-paclitaxel and Bevacizumab in Advanced, Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer

NCT ID: NCT06906341

This clinical trial is testing a new treatment approach for women with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. The study will examine how effective and safe a ...

Recruiting

Phase: PHASE2 Type: interventional Locations: San Francisco, California, United States, Leuven, , Belgium +37 more

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

NCT ID: NCT05735080

This clinical trial is studying a new oral medication called INX-315, which is being developed to treat advanced cancers, specifically hormone receptor-positive breast cancer and certain types of o...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Tacoma, Washington, United States +14 more

A Study to Investigate the Prevalence of Human Epidermal Growth Factor Receptor 2 (HER2) Immunohistochemistry (IHC) 3+ and Characterize the Clinicopathologic Features of Gynecologic Cancers in Taiwan

NCT ID: NCT06925113

This clinical trial is looking to understand the prevalence of a specific protein called HER2 in patients with advanced cervical, endometrial, and ovarian cancers in Taiwan. HER2 is important becau...

Recruiting

Type: observational Locations: Taipei, , Taiwan, Taipei, , Taiwan +5 more

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

NCT ID: NCT06395519

This clinical trial is studying a new medication called ETX-19477, which targets a specific enzyme involved in cancer growth. Researchers want to find out how safe the drug is, how the body process...

Recruiting

Phase: PHASE1 Type: interventional Locations: Rochester, Minnesota, United States, Boston, Massachusetts, United States +11 more

Phase 1b of Lurbinectedin in Combination With Weekly Paclitaxel and Bevacizumab in Platinum-resistant Ovarian Cancer

NCT ID: NCT05636111

This clinical trial is studying a new combination of treatments for women with advanced ovarian cancer that has not responded to standard platinum-based therapies. The researchers want to find out ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Individualized Response Assessment to Heated Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis From Ovarian, Colorectal, Appendiceal, or Peritoneal Mesothelioma Histologies

NCT ID: NCT04847063

This clinical trial is studying a treatment approach for patients with peritoneal carcinomatosis, which occurs when cancer spreads to the lining of the abdomen from cancers like ovarian, colorectal...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

NCT ID: NCT05891171

This clinical trial is studying a new treatment called AB598 for patients with advanced cancers, including types like bladder, cervical, lung, and breast cancer, among others. The main goal is to s...

Recruiting

Phase: PHASE1 Type: interventional Locations: Rochester, Minnesota, United States, New Orleans, Louisiana, United States +25 more

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Clinical Trials for Ovarian Cancer

406 Active Trials Found

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

Non-interventional Study to Collect Real-world Clinical and Patient-reported Outcomes in Ovarian Cancer

Proactive Hemodynamic Management During Cytoreductive Surgery and HIPEC

DT2216 + Paclitaxel in Platinum-Resistant Ovarian Cancer

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors

A Study of Second Look Laparoscopy (SLL) in People With Ovarian Cancer Who Have Completed Their First Course of Chemotherapy

Contribution of Preserving the Superior Left Colic Artery to the Vascularization of the Descending Colon Prior to Colorectal Anastomosis During Left-Sided or Rectal Resections for Colorectal or Ovarian Cancer. (Revascularisation Colique)

A Phase 1 Study of [225Ac]-FPI-1434 Injection

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer

Relacorilant in Combination With Nab-paclitaxel and Bevacizumab in Advanced, Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

A Study to Investigate the Prevalence of Human Epidermal Growth Factor Receptor 2 (HER2) Immunohistochemistry (IHC) 3+ and Characterize the Clinicopathologic Features of Gynecologic Cancers in Taiwan

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

Phase 1b of Lurbinectedin in Combination With Weekly Paclitaxel and Bevacizumab in Platinum-resistant Ovarian Cancer

Individualized Response Assessment to Heated Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis From Ovarian, Colorectal, Appendiceal, or Peritoneal Mesothelioma Histologies

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

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