Clinical Trials for Ovarian Neoplasms

Find clinical trials for ovarian neoplasms. Discover research opportunities and treatment options in your area.

45 Active Trials Found

Showing 45 trials on this page

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Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

NCT ID: NCT06885697

This clinical trial is studying a new treatment called TNhYP218 CAR T cells for patients with solid tumors, including mesothelioma and other cancers that express a protein called mesothelin. Mesoth...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

A Cohort Study of Hereditary Ovarian Cancer Risk Prediction Models and Pathogenesis Exploration

NCT ID: NCT06564428

This clinical trial is looking into hereditary ovarian cancer, specifically focusing on understanding the genetic factors that contribute to this condition. Researchers aim to create a model that c...

Recruiting

Type: observational Locations: Beijing, Beijing, China

A Study of SGN-MesoC2 in Advanced Solid Tumors

NCT ID: NCT06466187

This clinical trial is looking at a new treatment called SGN-MesoC2 for people with advanced solid tumors, which are types of cancer that start in organs like the lungs, pancreas, or ovaries. The s...

Recruiting

Phase: PHASE1 Type: interventional Locations: Birmingham, Alabama, United States, Boston, Massachusetts, United States +17 more

DOvEEgene/WISE Genomics: Diagnosing Ovarian and Endometrial Cancer Early Using Genomics

NCT ID: NCT02288676

The DOvEEgene clinical trial is focused on finding a new way to diagnose ovarian and endometrial cancers early. Researchers are developing a test that looks for specific changes in the DNA from sam...

Recruiting

Type: observational Locations: Montreal, Quebec, Canada, Montreal, Quebec, Canada

A Three-arm Randomized Phase II Study of Dostarlimab Alone or With Bevacizumab Versus Nonplatinum Chemotherapy in Recurrent Gynecological Clear Cell Carcinoma: DOVE (APGOT-OV7/ ENGOT-ov80 Study)

NCT ID: NCT06023862

This clinical trial, called the DOVE Study, is testing new treatment options for women with a specific type of cancer known as recurrent gynecological clear cell carcinoma. The trial compares three...

Recruiting

Phase: PHASE2 Type: interventional Locations: Singapore, , Singapore, Sendai, Miyagi, Japan +17 more

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

NCT ID: NCT05208762

This clinical trial is studying a new drug called PF-08046054/SGN-PDL1V to see how safe it is for patients with advanced solid tumors, which are cancers that have spread in the body or cannot be su...

Recruiting

Phase: PHASE1 Type: interventional Locations: Iowa City, Iowa, United States, Milano, , Italy +72 more

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

NCT ID: NCT04981119

This clinical trial is exploring how often certain solid tumors, like colorectal cancer and lung cancer, lose a specific gene marker called Human Leukocyte Antigen (HLA) and how this loss might aff...

Recruiting

Type: observational Locations: Palo Alto, California, United States, Rochester, Minnesota, United States +12 more

Ultrasound-guided Transvaginal Aspiration of Cystic Pelvic Lesions

NCT ID: NCT06988280

This clinical trial is studying a procedure called ultrasound-guided transvaginal aspiration, which is a way to drain fluid from cysts and abscesses in the pelvic area. These cysts can cause discom...

Recruiting

Type: observational Locations: Leuven, Vlaams Brabant, Belgium

DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations

NCT ID: NCT05786716

The DETERMINE Trial is investigating whether a combination of two cancer-fighting drugs, trastuzumab and pertuzumab, can help patients with various types of cancers that have specific changes in th...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Leeds, , United Kingdom +27 more

DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers.

NCT ID: NCT05768178

The DETERMINE Trial is studying the effects of two drugs, vemurafenib and cobimetinib, on adult patients with specific types of cancer that have a genetic change known as the BRAF V600 mutation. Wh...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Leeds, , United Kingdom +15 more

A Study of SGN-B6A in Advanced Solid Tumors

NCT ID: NCT04389632

This clinical trial is studying a new drug called sigvotatug vedotin (SGN-B6A) to see how safe it is and if it can help treat various advanced solid tumors, such as lung cancer, breast cancer, and ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States +182 more

Validation of the Sentinel Lymph Node Technique in Early-stage Ovarian Cancer (SENTOV II)

NCT ID: NCT06963268

The SENTOV II clinical trial is studying a new method called the sentinel lymph node (SLN) technique for women with early-stage ovarian cancer. This technique is being tested as a less invasive opt...

Not yet recruiting

Phase: PHASE3 Type: interventional Locations: Valencia, , Spain

A Study of LY4170156 in Participants With Selected Advanced Solid Tumors

NCT ID: NCT06400472

This clinical trial is studying a new drug called LY4170156 to see if it is safe and effective for people with advanced solid tumors, such as certain types of ovarian, endometrial, cervical, lung, ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Lyon, , France, New York, New York, United States +15 more

A Study of DM002 in Patients With Advanced Solid Tumors

NCT ID: NCT06751329

This clinical trial is studying a new medication called DM002 in patients with advanced solid tumors, including ovarian, prostate, endometrial, and colorectal cancers. The trial has two parts: the ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States, Wollongong, New South Wales, Australia

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

NCT ID: NCT06586957

This clinical trial is studying a new treatment called NKT3964 for adults with advanced or metastatic solid tumors, which are cancers that have spread beyond their original location. The trial aims...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Nashville, Tennessee, United States +6 more

Laparoscopic Interval Cytoreductive Surgery in Advance Ovarian Cancer

NCT ID: NCT06883409

This clinical trial is looking at a new way to perform surgery for women with advanced ovarian cancer. Specifically, it compares a less invasive type of surgery called laparoscopic surgery to tradi...

Recruiting

Phase: NA Type: interventional Locations: México City, Tlalpan, Mexico

A Trial to Evaluate the Safety of Niraparib Tablets in Adult Female Participants With Advanced or Relapsed Epithelial Ovarian Cancer

NCT ID: NCT06887933

This clinical trial is looking to understand how safe the medication niraparib is for adult women who have advanced or returning epithelial ovarian cancer. Niraparib is being studied for its effect...

Not yet recruiting

Phase: PHASE4 Type: interventional

A Study to Evaluate the Safety and Efficacy of A2B694, a Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

NCT ID: NCT06051695

This clinical trial is investigating a new treatment called A2B694 for patients with certain types of solid tumors, like colorectal cancer, pancreatic cancer, and lung cancer. The goal is to see if...

Recruiting

Phase: PHASE1 Type: interventional Locations: St. Louis, Missouri, United States, Rochester, Minnesota, United States +13 more

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

NCT ID: NCT04956640

This clinical trial is studying a new drug called LY3537982 to see if it is safe and effective for cancer patients who have a specific genetic mutation known as KRAS G12C. The trial is focused on p...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Lebanon, New Hampshire, United States +70 more

Phase I/II Clinical Study to Evaluate VB15010 Tablets in Patients With Advanced Solid Tumors

NCT ID: NCT06819215

This clinical trial is studying a new experimental treatment called VB15010, which is designed to help patients with advanced solid tumors, including various types of cancer like breast, ovarian, p...

Recruiting

Phase: PHASE1 Type: interventional Locations: Jinan, Shandong, China

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