Clinical Trials for Primary Open Angle Glaucoma

A Study of the Helix Surgical System in Primary Open-Angle Glaucoma (POAG) and Cataract (HELIX)

NCT ID: NCT06948773

The HELIX trial is a study looking at a new surgical system called the Helix Surgical System. It aims to evaluate how safe this system is for performing cataract surgery, particularly for patients ...

OMNI 3.0 Surgical System in Subjects With Primary Open-Angle Glaucoma

NCT ID: NCT06991270

The OMNI 3.0 Surgical System trial is designed to evaluate the safety and effectiveness of a new treatment for people with primary open-angle glaucoma (POAG), a common eye condition that can lead t...

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

NCT ID: NCT06822738

This clinical trial is studying a new treatment option for adults with primary open-angle glaucoma, a condition that can lead to vision loss if not properly managed. The trial is specifically looki...

Rocklatan Adds Pressure Reduction After MIGS (Minimally Invasive Glaucoma Surgery)

NCT ID: NCT07048886

This clinical trial is studying whether adding a medication called Rocklatan can further lower eye pressure in people with primary open-angle glaucoma who have already had a specific type of minima...

Hydrus® Microstent New Enrollment Post-Approval Study

NCT ID: NCT04553523

The Hydrus® Microstent New Enrollment Post-Approval Study is looking at the safety and effectiveness of a device called the Hydrus Microstent for patients with primary open-angle glaucoma. The goal...

XEN Glaucoma Gel Stent Versus Trabeculectomy

NCT ID: NCT05439161

This clinical trial is comparing two surgical options for treating different types of open-angle glaucoma: the XEN Glaucoma Gel Stent and traditional trabeculectomy. The goal is to see which proced...

Multicenter Glaucoma Study Investigating Standalone Canaloplasty

NCT ID: NCT05786196

This clinical trial is studying a procedure called canaloplasty, which is a treatment for primary open-angle glaucoma, a common eye condition that can lead to vision loss. Researchers want to find ...

Cataract Surgery in Conjunction With Ab-interno Canaloplasty Compared to Cataract Surgery Only in Patients With Mild to Moderate Primary Open-Angle Glaucoma

NCT ID: NCT05564091

This clinical trial is studying the effects of combining cataract surgery with a specific procedure called ab-interno canaloplasty in patients who have mild to moderate primary open-angle glaucoma....

Transcorneal Electrical Stimulation for the Treatment of Visual Field Defects in Patients With Open-Angle Glaucoma

NCT ID: NCT06682962

This clinical trial is looking at a new treatment called transcorneal electrical stimulation (TES) to help people with certain types of glaucoma regain some of their lost vision. Glaucoma is a cond...

Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study

NCT ID: NCT05695027

This clinical trial is studying whether a combination of two oral medications, nicotinamide and pyruvate, can help protect eye health in people with primary open-angle glaucoma. The goal is to see ...

Uddevalla Skövde Transscleral Micropulse Study

NCT ID: NCT05557721

Safety and Effectiveness of Minimally Invasive Micro Sclerostomy (MIMS®) to Reduce Intraocular Pressure in Open-Angle Glaucoma Which is Not Controlled Despite Polypharmacy

NCT ID: NCT06313749

This clinical trial is studying a new procedure called Minimally Invasive Micro Sclerostomy (MIMS®) to help lower eye pressure in patients with primary open-angle glaucoma who have not had success ...

A Study of AMDX-2011P in Participants With Primary Open Angle Glaucoma

NCT ID: NCT06223048

This clinical trial is studying a new treatment called AMDX-2011P, which aims to find amyloid deposits in the retina (the light-sensitive layer at the back of the eye) of people with Primary Open A...

The Objective is to Evaluate the Anterior Chamber Angle After BANG Procedure, the Study Will Recruit 12 Patients Who Will Undergo Planned Goniectomy for Uncontrolled POAG, Anterior Segment OCT Scan Will Be Used to Evaluate the Anterior Chamber Postoperatively.

NCT ID: NCT06526416

This clinical trial is looking at a specific eye surgery called the BANG procedure, which is designed to help patients with a condition known as primary open-angle glaucoma (POAG). The goal is to s...

CRISPR/Cas9 Instantaneous Gene Editing Therapy to Intraocular Hypertensive POAG With MYOC Mutation

NCT ID: NCT06465537

This clinical trial is studying a new treatment called CRISPR/Cas9 Instantaneous Gene Editing Therapy for people with primary open-angle glaucoma (POAG), a condition that can increase pressure insi...

Glaucoma, Visual Field Loss, and Their Association With Life Space in Older Adults

NCT ID: NCT04396002

This clinical trial is studying how primary open-angle glaucoma (POAG), a common eye condition that can gradually reduce vision, affects the ability of older adults to move around and participate i...

A Randomized, Open-label, Active-controlled, Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-angle Glaucoma or Ocular Hypertension

NCT ID: NCT06177678

This clinical trial is designed to test a new treatment called TFC-003 for patients with primary open-angle glaucoma or ocular hypertension, conditions that cause increased pressure in the eye and ...

Impact of Home Intraocular Pressure Telemonitoring on Intraocular Pressure Control and Glaucoma Progression

NCT ID: NCT05940623

This clinical trial is studying how home monitoring of eye pressure (intraocular pressure or IOP) can help people with glaucoma better manage their condition. Participants will be divided into two ...