Clinical Trials for Primary Sclerosing Cholangitis

Find clinical trials for primary sclerosing cholangitis. Discover research opportunities and treatment options in your area.

29 Active Trials Found

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Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research Approach

NCT ID: NCT04685200

This clinical trial is exploring the causes of primary sclerosing cholangitis (PSC), a rare liver disease that affects the bile ducts and can lead to serious complications like liver infections and...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

Oral Hymecromone to Treat Adolescents and Adults With Primary Sclerosing Cholangitis.

NCT ID: NCT05295680

This clinical trial is studying a medication called hymecromone to see if it can help treat adolescents and adults with a liver condition known as primary sclerosing cholangitis (PSC). The main goa...

Recruiting

Phase: PHASE2 Type: interventional Locations: Redwood City, California, United States, Stanford, California, United States

A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cholangitis (PSC)

NCT ID: NCT04663308

This clinical trial is studying an investigational drug called volixibat to see how well it helps reduce itching (pruritus) in patients with Primary Sclerosing Cholangitis (PSC), a liver disease. T...

Recruiting

Phase: PHASE2 Type: interventional Locations: Rochester, Minnesota, United States, Boston, Massachusetts, United States +113 more

Primary Sclerosing Cholangitis in Children

NCT ID: NCT04181138

This clinical trial is focused on understanding a rare liver disease called primary sclerosing cholangitis (PSC), which affects the bile ducts in the liver. The study aims to gather information abo...

Recruiting

Type: observational Locations: Aurora, Colorado, United States, Seattle, Washington, United States +10 more

LEOPARD Training and Validation Data Collection Study

NCT ID: NCT06675604

The LEOPARD Training and Validation Data Collection Study is a research project aimed at improving how doctors predict which patients on the waiting list for liver transplants are at the highest ri...

Recruiting

Type: observational Locations: Vienna, , Austria, Ghent, , Belgium +21 more

Evaluation of an Oral Microbiota-based Therapeutic as a Treatment Option for PSC

NCT ID: NCT06197308

This clinical trial is looking at a new treatment option for people with a liver condition called primary sclerosing cholangitis (PSC). The study will test the safety and feasibility of a therapy t...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Minneapolis, Minnesota, United States

Detoxification of the Liver In PSC (Dolphin)

NCT ID: NCT05835505

The Dolphin clinical trial is studying a new medication called BRS201 to see if it can help people with a condition called Primary Sclerosing Cholangitis (PSC), which affects the liver and bile duc...

Recruiting

Phase: PHASE2 Type: interventional Locations: Chestnut Hill, Massachusetts, United States

Pharmacologic Approaches to Preventing Primary Sclerosing Cholangitis Recurrence After Liver Transplantation

NCT ID: NCT06905054

This clinical trial is investigating whether a daily medication called fenofibrate can help prevent the return of a liver disease called primary sclerosing cholangitis (PSC) after a liver transplan...

Recruiting

Phase: PHASE2 Type: interventional Locations: Scottsdale, Arizona, United States

Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study

NCT ID: NCT05912387

This clinical trial is looking at the effects of statin therapy on patients with Primary Sclerosing Cholangitis (PSC), a serious liver disease that currently has no cure. PSC can lead to increased ...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Stanford, California, United States

FAecal Microbiota Transplantation in primaRy sclerosinG chOlangitis

NCT ID: NCT06286709

The FARGO trial is studying the effects of a treatment called Faecal Microbiota Transplantation (FMT) in patients with Primary Sclerosing Cholangitis (PSC) and inflammatory bowel disease (IBD). Thi...

Recruiting

Phase: PHASE2 Type: interventional Locations: Norwich, , United Kingdom, Oxford, , United Kingdom +4 more

Study with Norucholic Acid Tablets in Patients with Primary Sclerosing Cholangitis (PSC)

NCT ID: NCT06886360

This clinical trial is studying a treatment called norucholic acid, given in tablet form, for patients with a condition known as Primary Sclerosing Cholangitis (PSC). This trial is in the third pha...

Not yet recruiting

Phase: PHASE3 Type: interventional

CS0159 in Chinese Patients With PSC (Primary Sclerosing Cholangitis)

NCT ID: NCT05896137

This clinical trial is studying a new treatment called CS0159 for patients with Primary Sclerosing Cholangitis (PSC), a condition that affects the bile ducts in the liver. The trial is currently re...

Recruiting

Phase: PHASE2 Type: interventional Locations: Beijing, Beijing, China, Jinan, Shandong, China +11 more

Biobank for Cholestatic Liver Diseases.

NCT ID: NCT03445585

This clinical trial, titled "Biobank for Cholestatic Liver Diseases," is focused on collecting samples and health information from patients with certain liver diseases, specifically Primary Scleros...

Recruiting

Type: observational Locations: Rochester, Minnesota, United States, Rochester, Minnesota, United States

Characterization of Biliary Cell-derived Organoids from Bile of PSC and Non-PSC Patients

NCT ID: NCT04753996

This clinical trial is looking at bile samples and other medical information from patients with Primary Sclerosing Cholangitis (PSC) and healthy individuals. The goal is to better understand the ch...

Recruiting

Type: observational Locations: Rochester, Minnesota, United States

LEOPARD Prospective Validation Cohort 1

NCT ID: NCT06723275

The LEOPARD Prospective Validation Cohort 1 clinical trial is studying new ways to predict which patients with liver diseases are at the highest risk of needing a liver transplant and may not survi...

Not yet recruiting

Type: observational Locations: Ghent, , Belgium, Kiel, , Germany +3 more

MRI Based Biomarkers in Pediatric Autoimmune Liver Disease

NCT ID: NCT03175471

This clinical trial is looking at how MRI scans can help doctors understand and monitor two types of autoimmune liver diseases in young people: Autoimmune Hepatitis (AIH) and Primary Sclerosing Cho...

Recruiting

Type: observational Locations: Cincinnati, Ohio, United States

A-LiNK: Improving Outcomes in Autoimmune Liver Disease

NCT ID: NCT05750498

The A-LiNK trial is focused on improving care for children with autoimmune liver diseases, specifically Autoimmune Hepatitis (AIH) and Primary Sclerosing Cholangitis (PSC). The goal of this study i...

Recruiting

Type: observational Locations: Saint Louis, Missouri, United States, Cincinnati, Ohio, United States +6 more

MRI Biomarkers in as Predictor of Clinical Endpoints in Pediatric Autoimmune Liver Disease

NCT ID: NCT03178630

This clinical trial is studying how MRI scans can help predict the progression of autoimmune liver diseases, specifically in young people aged 6 to 23. Autoimmune liver diseases, like Autoimmune He...

Recruiting

Type: observational Locations: Cincinnati, Ohio, United States

A Study of SIPLIZUMAB in AILD and LT Patients

NCT ID: NCT06455280

This clinical trial is studying a medication called siplizumab to see if it can help patients with autoimmune liver disease (AILD) who are preparing for a liver transplant. AILD includes conditions...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States

Gluten-free Diet in PSC and IBD

NCT ID: NCT06026449

This clinical trial is studying whether a gluten-free diet can help patients with Primary Sclerosing Cholangitis (PSC) and Ulcerative Colitis (UC). PSC is a serious liver disease that often leads t...

Recruiting

Phase: NA Type: interventional Locations: Prague, , Czechia

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