Clinical Trials for Pulmonary Arterial Hypertension

Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

NCT ID: NCT06274801

The PROSERA-EXT trial is a research study looking at the long-term effects of a medication called seralutinib for adults with Pulmonary Arterial Hypertension (PAH), a condition that affects the blo...

Spironolactone for Pulmonary Arterial Hypertension

NCT ID: NCT01712620

This clinical trial is studying the effects of a medication called spironolactone on people with pulmonary arterial hypertension (PAH), a condition that causes high blood pressure in the lungs. PAH...

The Impact of ERA Switching on Risk Stratification in Pulmonary Arterial Hypertension

NCT ID: NCT07013149

This clinical trial is studying the effects of switching medications in patients with pulmonary arterial hypertension (PAH), a serious condition that affects blood flow in the lungs and can lead to...

Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial Hypertension

NCT ID: NCT06992440

This clinical trial is studying the effects of a medication called empagliflozin on improving heart function in people with a condition known as Pulmonary Arterial Hypertension (PAH). PAH is a seri...

A Study to Learn About the Study Medicine Called PF-07868489 in Healthy Adult People and in People With Pulmonary Arterial Hypertension

NCT ID: NCT06137742

This clinical trial is studying a new medication called PF-07868489 to see how well it is tolerated and how it works in both healthy adults and those with a condition called pulmonary arterial hype...

National Registry and Cohort Study of Pulmonary Vascular Disease

NCT ID: NCT05368467

This clinical trial is studying pulmonary arterial hypertension (PAH), a condition that affects the blood vessels in the lungs and can make it hard for patients to breathe. The goal of the study is...

A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-031/LIGHTRAY EXTENSION)

NCT ID: NCT06925750

This clinical trial, called the LIGHTRAY EXTENSION, is studying a medicine called sotatercept (MK-7962) for people with pulmonary arterial hypertension (PAH), a condition that affects blood flow in...

Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)

NCT ID: NCT05587712

This clinical trial is studying a medication called sotatercept to see how safe it is and how well it works in children aged 1 to 17 years who have Pulmonary Arterial Hypertension (PAH). PAH is a c...

imprOving Adherence to Pulmonary artErial hyperteNsion Treatment With teLemedicIne and patieNt guidaNce

NCT ID: NCT06850792

The clinical trial titled "imprOving Adherence to Pulmonary artErial hyperteNsion Treatment With teLemedicIne and patieNt guidaNce" is exploring how remote monitoring can help patients with pulmona...

Clinical Trial of 2-HOBA in Pulmonary Arterial Hypertension

NCT ID: NCT06176118

This clinical trial is studying a new treatment called 2-hydroxbenzylamine (2-HOBA) for people with pulmonary arterial hypertension (PAH), a serious condition that affects the blood vessels in the ...

Safety, Tolerability and Pharmacokinetics Study of L608 in Healthy Adults

NCT ID: NCT06429930

This clinical trial is studying a new medication called L608 to see if it is safe and well-tolerated in healthy adults. The goal is to test different doses of L608, starting from a small amount and...

Investigational Trial to Evaluate Safety and Tolerability of Treprostinil in Children Diagnosed With PAH

NCT ID: NCT06350032

This clinical trial is studying the safety and tolerability of a medication called preservative-free treprostinil in children diagnosed with pulmonary arterial hypertension (PAH), a serious conditi...

PulmonAry hyperteNsion DiagnOsis: a National cohoRt reseArch

NCT ID: NCT06998329

This clinical trial is studying Pulmonary Arterial Hypertension (PAH), a serious disease that affects the blood vessels in the lungs and can lead to heart problems. The main goal of the study is to...

China Pulmonary Vascular Disease Intervention Diagnosis and Management Study-right Heart Catheterization

NCT ID: NCT06954727

This clinical trial is looking at a procedure called right heart catheterization (RHC), which helps doctors diagnose and treat conditions related to high blood pressure in the lungs, known as pulmo...

Exercise Performance on Ambient Air vs. Low-Flow Oxygen Therapy in Pulmonary Vascular Disease (PVD)

NCT ID: NCT06384534

This clinical trial is looking to understand how exercise performance is affected by two different conditions: exercising in normal air versus exercising while using low-flow oxygen therapy. The st...

129 Xenon Imaging in Patients Treated With Sotatercept

NCT ID: NCT06351345

This clinical trial, called the "129 Xenon Imaging in Patients Treated with Sotatercept," is looking to see how well a special imaging technique called 129Xe MRI/MRS can help doctors monitor change...

Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs

NCT ID: NCT04930289

A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

NCT ID: NCT03683186

A Trial of "APL-9796'' in Adults With Pulmonary Hypertension

NCT ID: NCT06846554

The APL-9796 trial is a research study looking at a new treatment for adults with pulmonary arterial hypertension (PAH), a condition that affects the blood vessels in the lungs and can make it hard...

Artificial Intelligence-assisted Evaluation of Pulmonary HYpertension

NCT ID: NCT05566002

This clinical trial is studying how artificial intelligence (AI) can help in the evaluation and diagnosis of pulmonary hypertension, a serious condition that affects the blood vessels in the lungs....