Clinical Trials for Retinal Disease

Genotype-Phenotype Study of Patients With Plaquenil -Induced Retinal Toxicity, With Evaluation of the ABCA4 Gene

NCT ID: NCT01145196

This clinical trial is studying why some people who take the medication Plaquenil (used for autoimmune diseases like lupus and rheumatoid arthritis) develop eye problems called retinal toxicity, wh...

Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

NCT ID: NCT06891443

The HYPERION clinical trial is studying a new treatment called Sepofarsen for people with a specific type of genetic eye disease known as Leber Congenital Amaurosis (LCA) Type 10. This condition ca...

National Eye Institute Biorepository for Retinal Diseases

NCT ID: NCT01496625

The National Eye Institute Biorepository for Retinal Diseases is a study aimed at understanding various eye conditions, including Age-Related Macular Degeneration and Diabetic Retinopathy. Research...

Cell Collection to Study Eye Diseases

NCT ID: NCT01432847

This clinical trial is focused on studying eye diseases that affect the retina, specifically Best Vitelliform Dystrophy (Best disease), Late-Onset Retinal Degeneration (L-ORD), and Age-Related Macu...

A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edema

NCT ID: NCT06305416

This clinical trial is studying the effectiveness and safety of a medication called Ranibizumab for treating diabetic macular edema (DME), a condition that can cause vision loss in people with diab...

CHOPXE - Analysis of Choriocapillaris Flow Deficits in Patients With Pseudoxanthoma Elasticum

NCT ID: NCT07006649

The CHOPXE clinical trial is studying a condition called pseudoxanthoma elasticum (PXE), which is a rare genetic disorder that can affect the skin and eyes, potentially leading to vision problems. ...

Study to Evaluate Ultevursen in Subjects With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene

NCT ID: NCT06627179

This clinical trial is investigating a treatment called Ultevursen for adults and children with Retinitis Pigmentosa (RP) caused by specific mutations in a gene known as USH2A. The goal is to see i...

COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease

NCT ID: NCT06380075

This clinical trial is studying two different ultrawide field cameras that take pictures of the back of the eye to see how well they work for checking and monitoring inherited retinal diseases (IRD...

Inherited Retinal Degenerative Disease Registry

NCT ID: NCT02435940

The Inherited Retinal Degenerative Disease Registry, known as the My Retina Tracker® Registry, is a study designed for individuals affected by certain rare eye diseases that can lead to vision loss...

A Long-Term Follow-Up Study in Subjects Who Received vMCO-I Administered Via Intravitreal Injection

NCT ID: NCT05921162

Stem Cell Ophthalmology Treatment Study II

NCT ID: NCT03011541

The Stem Cell Ophthalmology Treatment Study II is a clinical trial investigating the use of stem cells derived from a patient’s own bone marrow to treat various eye conditions that cause damage to ...

Advancing Pediatric Retinal Imaging With Auto-aligned OCT

NCT ID: NCT06841575

This clinical trial is testing a new handheld device that can take pictures of the retina, which is the light-sensitive layer at the back of the eye. The device has a special feature that helps it ...

MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby)

NCT ID: NCT06455826

The Wallaby trial is a research study looking at a new treatment called VP-001 for people with a specific genetic condition known as PRPF31 mutation-associated retinal dystrophy, which can lead to ...

A Study of Two Doses of VP-001 Administered Intravitreally in Participants with Confirmed PRPF31 Mutation-Associated Retinal Dystrophy Previously Treated with VP001

NCT ID: NCT06852963

This clinical trial is studying a treatment called VP-001 for people with a specific type of vision loss known as Retinitis Pigmentosa, which is caused by a mutation in the PRPF31 gene. The researc...

Intraoperative OCT Guidance of Intraocular Surgery II

NCT ID: NCT03713268

This clinical trial, called "Intraoperative OCT Guidance of Intraocular Surgery II," is exploring a new technology that helps doctors see detailed images of the eye during surgery. The goal is to i...

Peripheral Retina Robotically Aligned OCT Study

NCT ID: NCT06451068

The Peripheral Retina Robotically Aligned OCT Study is exploring a new imaging technology called optical coherence tomography (OCT) to better view the edges of the retina, which is the light-sensit...

Retina BioBank: Retina Biomarkers for a Deeper Understanding of Vitreoretinal and Systemic Diseases

NCT ID: NCT06796673

Safety and Tolerability of IRX-101 in Patients Receiving Intravitreal Injections

NCT ID: NCT05750589

This clinical trial is studying a new treatment called IRX-101 to see how safe and tolerable it is for patients who are receiving eye injections for retinal diseases. The trial compares IRX-101 to ...

Optimize Pediatric OCT Imaging

NCT ID: NCT06139523

This clinical trial, called "Optimize Pediatric OCT Imaging," is trying to find out which of two new imaging systems can better capture pictures of the retina in children. The retina is the part of...

Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.

NCT ID: NCT06394232

This clinical trial is focused on testing a new treatment called Eyecyte-RPE™ for patients with Geographic Atrophy (GA), a serious eye condition that can lead to vision loss due to dry age-related ...