Clinical Trials for SCLC

Find clinical trials for sclc. Discover research opportunities and treatment options in your area.

18 Active Trials Found

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Lurbinectedin With Berzosertib, an ATR Kinase Inhibitor in Small Cell Cancers and High-Grade Neuroendocrine Cancers

NCT ID: NCT04802174

This clinical trial is studying a combination of two drugs, lurbinectedin and berzosertib, to see if they can effectively shrink tumors in patients with small cell lung cancer (SCLC) and high-grade...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors

NCT ID: NCT04826341

This clinical trial is investigating a new treatment combination for patients with small cell lung cancer (SCLC), extra-pulmonary small cell neuroendocrine cancer, or certain cancers that have beco...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

SLV-154 Treatment of Metastatic Solid Tumors

NCT ID: NCT06771219

This clinical trial is studying a new treatment called SLV-154 for patients with certain types of metastatic solid tumors, which are cancers that have spread from their original site to other parts...

Recruiting

Phase: PHASE1 Type: interventional Locations: St. Louis, Missouri, United States, Saint Louis, Missouri, United States +2 more

A Study of ZL-1310 in Subjects With Small Cell Lung Cancer

NCT ID: NCT06179069

This clinical trial, called a Phase 1 study, is testing a new treatment called ZL-1310 in patients with small cell lung cancer (SCLC). The researchers want to see how safe the treatment is, how wel...

Recruiting

Phase: PHASE1 Type: interventional Locations: Hackensack, New Jersey, United States, Duarte, California, United States +38 more

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT ID: NCT04585750

The PYNNACLE clinical trial is studying a new treatment called PC14586, aimed at patients with advanced solid tumors that have a specific genetic mutation known as TP53 Y220C. This trial is current...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Charleston, South Carolina, United States +90 more

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

NCT ID: NCT06657222

This clinical trial is testing a new drug called TUB-030 to see if it can effectively treat advanced solid tumors, including types like head and neck cancer, lung cancer, and triple-negative breast...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Cleveland, Ohio, United States +6 more

Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy

NCT ID: NCT05703269

This clinical trial is looking to find out whether giving a lower dose of radiation over several days (called fractionated stereotactic radiosurgery, or FSRS) is better at reducing side effects com...

Recruiting

Phase: NA Type: interventional Locations: Flint, Michigan, United States, Effingham, Illinois, United States +49 more

MOnaliZumab in Combination With durvAlumab (MEDI4736) Plus Platinum-based chemotheRapy for First-line Treatment of Extensive Stage Small Cell Lung Cancer

NCT ID: NCT05903092

This clinical trial is studying a new treatment combination for patients with extensive stage small cell lung cancer (SCLC), a type of lung cancer that has spread widely in the body. The treatment ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Iowa City, Iowa, United States, Charlottesville, Virginia, United States +3 more

Study of Oral MRT-2359 in Selected Cancer Patients

NCT ID: NCT05546268

This clinical trial is studying a new treatment called MRT-2359 for patients with specific types of cancer, including non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), and certain ...

Recruiting

Phase: PHASE1 Type: interventional Locations: New Haven, Connecticut, United States, New York, New York, United States +21 more

Irinotecan Liposome(II) Combined With Ivonescimab as Second-line Treatment for Small Cell Lung Cancer : A Prospective, Single-arm, Multicenter Clinical Study

NCT ID: NCT06820762

This clinical trial is investigating a new treatment option for small cell lung cancer (SCLC) using a combination of two drugs: irinotecan liposome(II) and Ivonescimab. This study is designed for p...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Shenyang, , China, Dalian, Liaoning, China +1 more

PM8002 in Combination With Paclitaxel Compared With Chemotherapy as Second-line Treatment in Small Cell Lung Cancer

NCT ID: NCT06616532

This clinical trial is studying a new treatment for small cell lung cancer (SCLC), specifically looking at the combination of a drug called PM8002 with Paclitaxel. PM8002 is a special type of medic...

Recruiting

Phase: PHASE3 Type: interventional Locations: Nanjing, , China, Xuzhou, , China +48 more

Cognitive Screening in Lung Cancer Patients

NCT ID: NCT06727370

This clinical trial is looking at how lung cancer and its treatments might affect thinking and memory in patients. Specifically, it focuses on those with non-small cell lung cancer (NSCLC) and smal...

Recruiting

Type: observational Locations: Milano, , Italy

GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2

NCT ID: NCT05130255

The GD2-SADA:177Lu-DOTA clinical trial is studying a new treatment for patients with certain types of solid tumors, including Small Cell Lung Cancer, Malignant Melanoma, Sarcoma, and High-Risk Neur...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chicago, Illinois, United States, Duarte, California, United States +6 more

Observational Study to Evaluate the Safety and Efficacy of Zepzelca™ Injection

NCT ID: NCT06021483

This clinical trial is studying the safety and effectiveness of a medication called Zepzelca™ injection for patients with small cell lung cancer (SCLC) who have not responded to initial chemotherap...

Recruiting

Type: observational Locations: Seoul, , Korea, Republic Of

Milaberon in Advanced Solid Tumors: an Open, Multicenter Clinical Study

NCT ID: NCT06534762

This clinical trial is investigating a medication called Milaberon in patients with advanced solid tumors, including lung cancer, colorectal cancer, pancreatic cancer, triple-negative breast cancer...

Recruiting

Phase: PHASE2 Type: interventional Locations: Hangzhou, Zhejiang, China, Hangzhou, Zhejiang, China

Adebrelimab + Apatinib in SCLC Maintenance Therapy

NCT ID: NCT06475209

This clinical trial is studying a new treatment approach for patients with extensive-stage small cell lung cancer (SCLC) using a combination of two medications: Adebrelimab and Apatinib. The goal i...

Recruiting

Phase: PHASE2 Type: interventional Locations: Xi'an, Shannxi, China

Toripalimab Plus Anlotinib for the Maintenance of Extensive Stage Small Cell

NCT ID: NCT06441344

This clinical trial is studying a new treatment approach for patients with extensive stage small cell lung cancer (SCLC). The trial is exploring whether combining two drugs, toripalimab and anlotin...

Not yet recruiting

Phase: PHASE3 Type: interventional

Online Adaptive Radiotherapy Using a Novel Linear Accelerator (ETHOS)

NCT ID: NCT06116019

This clinical trial is studying a new way of delivering radiation therapy called online adaptive radiotherapy (ART) using a special machine called the ETHOS treatment system. This approach allows d...

Recruiting

Type: observational Locations: Berlin, , Germany

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