Clinical Trials for Small Cell Lung Carcinoma

A Study of Hospital-at-Home for People Receiving Tarlatamab

NCT ID: NCT06957314

This clinical trial is exploring a new way to care for patients with extensive stage small cell lung cancer (ES-SCLC) who are receiving a treatment called tarlatamab. The study is comparing a progr...

Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)

NCT ID: NCT02628067

This clinical trial is studying a medication called pembrolizumab (MK-3475) for people with advanced solid tumors that have not responded to standard treatments. The trial aims to see how well this...

Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)

NCT ID: NCT04938817

This clinical trial is exploring new treatment options for patients with extensive-stage small cell lung cancer (ES-SCLC) who need a second line of therapy after their initial treatment. The study ...

Durvalumab Maintenance After Thoracic Chemoradiotherapy in Frail Small Cell Lung Cancer Patients Whose Disease is Limited to the Thorax

NCT ID: NCT05617963

The DURVALUNG study is a clinical trial aimed at exploring whether a medication called durvalumab can help frail patients with limited small cell lung cancer (SCLC) after they have received chemoth...

DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

NCT ID: NCT05882058

The DAREON™-5 clinical trial is studying a new treatment called BI 764532 for adults with advanced small cell lung cancer or other neuroendocrine cancers. This trial aims to find out the right dose...

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

NCT ID: NCT06131840

This clinical trial is investigating an experimental drug called PF-08046050, which is designed to treat adults with advanced solid tumors, including types of cancer like colorectal, stomach, pancr...

Dose-Escalation Radiotherapy in Limited-Stage Small Cell Lung Cancer: A Phase III Randomized Trial

NCT ID: NCT07015892

This clinical trial is studying a new approach to treat limited-stage small cell lung cancer (SCLC) by increasing the dose of radiotherapy given to patients who are already receiving standard chemo...

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BMS-986489 in Chinese Participants With Relapsed/Refractory Small Cell Lung Cancer

NCT ID: NCT06799286

This clinical trial is studying a new medication called BMS-986489 to see how safe it is, how well it’s tolerated, and whether it might help people with relapsed or refractory small cell lung cance...

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT ID: NCT04585750

The PYNNACLE clinical trial is studying a new treatment called PC14586, aimed at patients with advanced solid tumors that have a specific genetic mutation known as TP53 Y220C. This trial is current...

Durvalumab After Chemoradiotherapy in Limited Stage Small Cell Lung Cancer.

NCT ID: NCT06992609

The clinical trial titled "Durvalumab After Chemoradiotherapy in Limited Stage Small Cell Lung Cancer" is looking at a new treatment option for patients diagnosed with limited-stage small cell lung...

Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors

NCT ID: NCT07006727

This clinical trial is studying a new treatment called [225Ac]Ac-ETN029 for patients with advanced cancers that express a protein known as DLL3. These cancers include small cell lung carcinoma, lar...

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

NCT ID: NCT05419076

This clinical trial is studying a treatment called stereotactic radiosurgery (SRS) for patients who have been diagnosed with small cell lung cancer that has spread to the brain. The goal is to find...

Maintenance Durvalumab (MEDI4736) and Olaparib (AZD2281) After Standard 1st Line Treatment (Carboplatin/Cisplatin, Etoposide, Durvalumab) in HRD Positive Extensive Disease (ED) Small-cell Lung Cancer (SCLC)

NCT ID: NCT06419179

PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56

NCT ID: NCT04199741

This clinical trial is studying a new imaging technique called 89Zr-DFO-SC16.56 to see how safe it is and how the body processes it in people with small cell lung cancer, a type of lung cancer that...

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

NCT ID: NCT05616624

This clinical trial is studying a new treatment approach for patients with advanced lung cancer who have not responded to their initial therapy. In this study, patients with either small cell lung ...

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

NCT ID: NCT06586957

This clinical trial is studying a new treatment called NKT3964 for adults with advanced or metastatic solid tumors, which are cancers that have spread beyond their original location. The trial aims...

Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer

NCT ID: NCT05620342

This clinical trial is studying a new experimental treatment for lung cancer, specifically targeting patients with advanced small cell lung carcinoma or non-small cell lung cancer who have not resp...

Molecular Analysis and Treatment Options of SCLC

NCT ID: NCT05945745

This clinical trial is studying small cell lung cancer (SCLC), a fast-growing cancer that often spreads quickly and is challenging to treat. While patients usually respond well to initial chemother...

Prospective, Longitudinal Biocollection in Thoracic Oncology, Including Newly Diagnosed Lung Cancer Patients

NCT ID: NCT06481813

This clinical trial is focused on collecting important health information from patients with lung cancer, specifically those newly diagnosed with different types of lung cancer, such as non-small c...

Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer

NCT ID: NCT05450965

This clinical trial is studying a new drug called onvansertib to see how safe and effective it is for treating patients with relapsed small cell lung cancer (SCLC). This trial is specifically for p...