Clinical Trials for Solid Tumor, Adult

An Exploratory Study to Evaluate Immune Determinants of the Response to Adoptive Cell Therapy (ACT) in Solid and Hematologic Tumors

NCT ID: NCT05481502

This clinical trial is investigating how certain treatments called adoptive cell therapy (ACT) affect the immune system in patients with solid tumors and blood cancers. Researchers want to understa...

A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring

NCT ID: NCT06788509

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

NCT ID: NCT06326411

This clinical trial is studying a new oral medication called NST-628 to see how safe and effective it is for adults with certain types of advanced solid tumors that have specific genetic mutations....

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

NCT ID: NCT06625775

The BREAKER-101 clinical trial is a study looking at a new treatment called BBO-10203 for patients with advanced solid tumors, including certain types of breast and colorectal cancers. This is the ...

A Phase 1/2a Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

NCT ID: NCT07020221

This clinical trial is studying a new treatment called VS-7375 for patients with certain types of advanced solid tumors that have a specific genetic change known as the KRAS G12D mutation. The goal...

A Study of CF33-hNIS (VAXINIA), an Oncolytic Virus, as Monotherapy or in Combination With Pembrolizumab in Adults With Metastatic or Advanced Solid Tumors

NCT ID: NCT05346484

This clinical trial is studying a new treatment called CF33-hNIS (VAXINIA), which is an oncolytic virus designed to target and kill cancer cells, particularly in patients with advanced solid tumors...

ProofPrincip IntraTu TCells SinglDoseImmunCheckpoinInhib Gastro-Esophage Adenocarcinoma w/ARID1a Mu

NCT ID: NCT06824363

This clinical trial is designed to test a new treatment approach for patients with specific types of stomach and esophageal cancers that have a mutation in a gene called ARID1A. The study aims to s...

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

NCT ID: NCT06682793

This clinical trial is testing a new treatment called A2B395 for patients with certain types of solid tumors, such as colorectal cancer, lung cancer, and triple-negative breast cancer. The main goa...

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

NCT ID: NCT06917079

This clinical trial is testing a new treatment called BBO-11818 for adults with certain types of cancer that have a specific genetic mutation known as KRAS. The trial is looking at the safety of th...

Phase 1 Study of GEN2 in Patients With Advanced Solid Tumors

NCT ID: NCT06391918

The clinical trial titled "Phase 1 Study of GEN2 in Patients With Advanced Solid Tumors" is investigating a new treatment called GEN2 for adults with advanced solid tumors that have not responded t...

Phase 1 Open-Label Study BL-M17D1 w/HER2-Expressing/Mutant Advanced or Metastatic Solid Tumors

NCT ID: NCT06714617

This clinical trial is investigating a new treatment called BL-M17D1 for patients with advanced or metastatic solid tumors that have a specific protein called HER2. The study aims to evaluate how s...

UCSF Biobank for Hereditary Cancers and Tumor-Associated Mutations

NCT ID: NCT06895681

The UCSF Biobank for Hereditary Cancers and Tumor-Associated Mutations is a research study aimed at collecting and storing samples from people with hereditary cancers. The goal is to create models ...

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

NCT ID: NCT06265727

This clinical trial, called a Phase 1/2 study, is looking at a new treatment called CRB-701 for adults with solid tumors that express a protein known as nectin-4. The main goal is to find out what ...

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

NCT ID: NCT06244771

This clinical trial is studying a new treatment called FMC-376 for patients with advanced solid tumors that have a specific genetic change known as the KRAS G12C mutation. These tumors can include ...

Probiotic Supplementation During Cytotoxic Chemotherapy for Solid Tumor Malignancies

NCT ID: NCT06772090

This clinical trial is looking at the effects of a probiotic supplement in adults with stage III colon cancer who are receiving chemotherapy. Probiotics are good bacteria that can help improve gut ...

IMA401 TCER® in Recurrent and/or Refractory Solid Tumors, Alone or in Combination With a Checkpoint Inhibitor

NCT ID: NCT05359445

This clinical trial is studying a new treatment called IMA401 for adults with advanced solid tumors that have either come back after treatment or have not responded to standard therapies. The main ...

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

NCT ID: NCT04981119

This clinical trial is exploring how often certain solid tumors, like colorectal cancer and lung cancer, lose a specific gene marker called Human Leukocyte Antigen (HLA) and how this loss might aff...

Diagnostic Efficacy and Dosimetry of MNPR-101-DFO*-89Zr in Patients With Solid Tumors

NCT ID: NCT06337084

This clinical trial is testing a new imaging agent called MNPR-101-DFO*-89Zr to see how well it can help doctors locate tumors in patients with solid tumors, which can include types of cancer like ...

Open-Label, Dose-Escalation With Expansion to Assess the Safety, Tolerability, and PK of TRE-515 in Subjects With Solid Tumors

NCT ID: NCT05055609

This clinical trial is studying a new oral medication called TRE-515, aimed at treating adults with solid tumors, which are types of cancers that form in various tissues like organs. The main goal ...

Dose-Escalation of MNPR-101-PCTA-177Lu in Solid Tumors

NCT ID: NCT06617169

This clinical trial is looking at a new treatment called MNPR-101-PCTA-177Lu for patients with solid tumors, including types of cancer such as bladder, breast, lung, colorectal, gastric, ovarian, a...