Clinical Trials for Systemic Lupus Erythematosus

A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE)

NCT ID: NCT06411249

This clinical trial is studying the effectiveness and safety of a medication called belimumab in adults who have been diagnosed with early systemic lupus erythematosus (SLE) and are still experienc...

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies.

NCT ID: NCT06916806

This clinical trial is designed to test a new medication called AZD5492 in adults with two specific autoimmune diseases: Systemic Lupus Erythematosus (SLE) and Idiopathic Inflammatory Myopathies (I...

A Study of GNC-038 Tetra-specific Antibody Injection in Patients With Systemic Lupus Erythematosus

NCT ID: NCT06857214

This clinical trial is studying a new treatment called GNC-038, which is an injection designed for patients with systemic lupus erythematosus (SLE), a condition where the immune system attacks the ...

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

NCT ID: NCT05843643

This clinical trial is studying the safety and effectiveness of a medication called upadacitinib for adults with moderate to severe systemic lupus erythematosus (SLE), a disease that causes inflamm...

Efficacy And Safety Of MK-6194 In Adult Participants With Systemic Lupus Erythematosus (MK-6194-006)

NCT ID: NCT06161116

This clinical trial is studying a new treatment called MK-6194 for adults with Systemic Lupus Erythematosus (SLE), a condition where the immune system mistakenly attacks healthy tissues. The main g...

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

NCT ID: NCT05835310

This clinical trial is studying a medication called Anifrolumab, which is given through an intravenous (IV) line, to see how well it works and how safe it is for treating children with a condition ...

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

NCT ID: NCT06121297

The RESET-SLE trial is studying a new treatment called CABA-201 for people with active Systemic Lupus Erythematosus (SLE), including those with a specific kidney-related form known as Lupus Nephrit...

A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)

NCT ID: NCT05869955

This clinical trial is investigating a new treatment called CC-97540, which uses special immune cells (CAR T cells) designed to target a protein involved in certain autoimmune diseases. The goal of...

A Study of CNTY-101 in Participants With Refractory B Cell-mediated Autoimmune Diseases

NCT ID: NCT06255028

The CALiPSO-1 trial is studying a new treatment called CNTY-101 for people who have serious autoimmune diseases, specifically systemic lupus erythematosus (SLE) and lupus nephritis (LN), and who ha...

Study of Systemic Lupus Erythematosus

NCT ID: NCT00001372

This clinical trial is studying systemic lupus erythematosus (SLE), an autoimmune disease where the body's immune system mistakenly attacks its own tissues. The researchers want to understand how S...

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

NCT ID: NCT06617325

This clinical trial is studying a new treatment called dapirolizumab pegol (DZP) for people with moderately to severely active systemic lupus erythematosus (SLE), a chronic autoimmune disease that ...

A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus

NCT ID: NCT04976322

A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Pharmacodynamics, and Efficacy of P-CD19CD20-ALLO1 in Participants With Severe, Treatment-refractory Systemic Lupus Erythematosus (SLE)

NCT ID: NCT06984341

This clinical trial is studying a new treatment called P-CD19CD20-ALLO1 for people with severe systemic lupus erythematosus (SLE), a condition that can cause serious health problems. The trial aims...

A First-in-Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7507062 in Participants With Systemic Lupus Erythematosus

NCT ID: NCT05835986

This clinical trial is investigating a new medication called RO7507062 to see if it is safe and how it works in people with systemic lupus erythematosus (SLE), a condition where the immune system a...

Clinical and Demographic Features of Patients With Moderate to Severe Active Systemic Lupus Erythematosus in Russia

NCT ID: NCT06759519

This clinical trial is focused on understanding the characteristics of patients with moderate to severe active systemic lupus erythematosus (SLE), a complex autoimmune disease where the body's immu...

Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders

NCT ID: NCT06434363

This clinical trial is exploring a new treatment involving a combination of specialized immune cells, a medication called tafasitamab, and chemotherapy for patients with autoimmune disorders, speci...

A Phase 1b Study of Budoprutug in Systemic Lupus Erythematosus (SLE)

NCT ID: NCT07011043

This clinical trial is studying a new treatment called budoprutug for adults with systemic lupus erythematosus (SLE), a condition where the immune system attacks the body’s own tissues. The main go...

Long-Term Outcomes in SLE at Peking University People's Hospital

NCT ID: NCT07005479

This clinical trial at Peking University People's Hospital is studying long-term outcomes for patients with Systemic Lupus Erythematosus (SLE), a condition that affects the immune system. Researche...

A Phase 2a Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

NCT ID: NCT06570798

This clinical trial is looking at two medications, inebilizumab and blinatumomab, to see how safe and well-tolerated they are for adults with certain autoimmune diseases, specifically systemic lupu...

Fatigue in Lupus Intervention Programmes (FLIP)

NCT ID: NCT06308770

The Fatigue in Lupus Intervention Programmes (FLIP) trial is studying ways to help people with Systemic Lupus Erythematosus (SLE) manage their fatigue, which can greatly affect their daily lives. T...