Clinical Trials for Systemic Lupus Erythematosus

Find clinical trials for systemic lupus erythematosus. Discover research opportunities and treatment options in your area.

160 Active Trials Found

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A Phase 2a Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

NCT ID: NCT06570798

This clinical trial is looking at two medications, inebilizumab and blinatumomab, to see how safe and well-tolerated they are for adults with certain autoimmune diseases, specifically systemic lupu...

Recruiting

Phase: PHASE2 Type: interventional Locations: Cleveland, Ohio, United States, Madrid, , Spain +24 more

Long-Term Outcomes in SLE at Peking University People's Hospital

NCT ID: NCT07005479

This clinical trial at Peking University People's Hospital is studying long-term outcomes for patients with Systemic Lupus Erythematosus (SLE), a condition that affects the immune system. Researche...

Recruiting

Type: observational Locations: Beijing, Beijing, China

Fatigue in Lupus Intervention Programmes (FLIP)

NCT ID: NCT06308770

The Fatigue in Lupus Intervention Programmes (FLIP) trial is studying ways to help people with Systemic Lupus Erythematosus (SLE) manage their fatigue, which can greatly affect their daily lives. T...

Recruiting

Phase: NA Type: interventional Locations: Edinburgh, , United Kingdom

Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 2)

NCT ID: NCT05624749

This clinical trial, called SIRIUS-SLE 2, is studying a new treatment called ianalumab for patients with systemic lupus erythematosus (SLE), a condition that can cause inflammation and damage in va...

Recruiting

Phase: PHASE3 Type: interventional Locations: Baltimore, Maryland, United States, Philadelphia, Pennsylvania, United States +134 more

Two-period Crossover Study to Demonstrate the Comparability of Pharmacokinetics of Subcutaneous Ianalumab Between 2mL Auto-injector/2mL PFS with1mL Pre-filled Syringe in Adult Participants With Autoimmune Disease

NCT ID: NCT06293365

This clinical trial is studying a medication called ianalumab, which is being tested to see how well it works and is absorbed in the body when given through two different types of injections for pe...

Recruiting

Phase: PHASE2 Type: interventional Locations: Madrid, , Spain, Hamilton, Ontario, Canada +37 more

Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).

NCT ID: NCT06133972

This clinical trial, called the SIRIUS-SLE Extension study, is looking at the long-term safety of a treatment called ianalumab for people with systemic lupus erythematosus (SLE), a condition that c...

Recruiting

Phase: PHASE3 Type: interventional Locations: Madrid, , Spain, Leipzig, , Germany +71 more

Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1)

NCT ID: NCT05639114

The SIRIUS-SLE 1 trial is a research study looking at how well two different ways of using a medication called ianalumab work for people with systemic lupus erythematosus (SLE), a condition where t...

Recruiting

Phase: PHASE3 Type: interventional Locations: Pittsburgh, Pennsylvania, United States, La Jolla, California, United States +193 more

BAFF CAR-T Cells (LMY-920) for Systemic Lupus Erythematosus

NCT ID: NCT06340750

This clinical trial is studying a new treatment called BAFF CAR-T cells (LMY-920) for adults with systemic lupus erythematosus (SLE), a chronic autoimmune disease where the body's immune system mis...

Recruiting

Phase: PHASE1 Type: interventional Locations: Columbus, Ohio, United States

Prospective Registry Investigating Maternal and Infant Outcomes in Anifrolumab Users

NCT ID: NCT06659029

The PRIMULA Preg study is looking at how the medication anifrolumab affects pregnant women with systemic lupus erythematosus (SLE) and their babies. This study is important because it aims to under...

Recruiting

Type: observational Locations: Las Vegas, Nevada, United States

A Treatment Effectiveness Study Among SLE Patients Receiving Anifrolumab in Routine Clinical Practice

NCT ID: NCT05637112

The ASTER study is looking at how effective a new treatment called anifrolumab is for patients with Systemic Lupus Erythematosus (SLE) in everyday medical practice. This study aims to gather real-w...

Recruiting

Type: observational Locations: Paris, , France, Berlin, , Germany +209 more

A Phase Ib Study of QLS4131 in Subjects With Systemic Lupus Erythematosus

NCT ID: NCT07001839

This clinical trial is studying a new treatment called QLS4131 for people with Systemic Lupus Erythematosus (SLE), a condition where the immune system mistakenly attacks the body. The main goals ar...

Not yet recruiting

Phase: PHASE1 Type: interventional

Anifrolumab Malignancy and Serious Infections Study

NCT ID: NCT07000110

The Anifrolumab Malignancy and Serious Infections Study is looking at the safety of a medication called anifrolumab for patients with moderate to severe Systemic Lupus Erythematosus (SLE), which is...

Not yet recruiting

Type: observational

REACT-01: Reversing Autoimmunity Through Cell Therapy

NCT ID: NCT06465147

The REACT-01 trial is a research study aimed at finding out if a new type of treatment can help children and young adults with Systemic Lupus Erythematosus (SLE) who have not responded well to exis...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States

Medical Follow-up of New Cases of Polyarthritis in Children and Young Adults

NCT ID: NCT07000916

This clinical trial is studying how to better monitor and manage new cases of certain types of arthritis and autoimmune diseases in children and young adults. The conditions being looked at include...

Recruiting

Type: observational Locations: Brussels, , Belgium

Anti-CD19 CAR-NK Cells in Refractory/Relapsed Systemic Lupus Erythematosus

NCT ID: NCT06421701

This clinical trial is investigating a new treatment called anti-CD19 CAR-NK cells for patients with systemic lupus erythematosus (SLE) who have not responded to standard therapies or have had a re...

Recruiting

Phase: PHASE1 Type: interventional Locations: Hangzhou, , China

Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer

NCT ID: NCT03816345

This clinical trial is studying how well a medication called nivolumab works for patients who have autoimmune disorders and advanced cancers that are difficult to treat or remove with surgery. Nivo...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chicago, Illinois, United States, New Haven, Connecticut, United States +56 more

A Study to Evaluate Effectiveness and Safety of Deucravacitinib (BMS-986165) Compared With Placebo in Participants With Active Systemic Lupus Erythematosus

NCT ID: NCT05620407

This clinical trial is studying a new medication called deucravacitinib to see how effective and safe it is for people with active systemic lupus erythematosus (SLE), a condition that can cause inf...

Recruiting

Phase: PHASE3 Type: interventional Locations: Ann Arbor, Michigan, United States, Boston, Massachusetts, United States +424 more

Transcutaneous Vagus Nerve Stimulation in SLE

NCT ID: NCT06987565

This clinical trial is studying a new treatment for patients with systemic lupus erythematosus (SLE), a chronic disease that often causes joint and muscle pain as well as fatigue. Researchers are e...

Not yet recruiting

Phase: PHASE2 Type: interventional

The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVD

NCT ID: NCT05440422

This clinical trial, called IFN-CVD, is studying whether a drug named anifrolumab can help improve blood vessel health in people with systemic lupus erythematosus (SLE). People with SLE often face ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy, in Patients With Refractory Systemic Lupus Erythematosus (GALLOP)

NCT ID: NCT06752876

The GALLOP clinical trial is testing a new treatment for patients with a severe form of Systemic Lupus Erythematosus (SLE), a condition that can affect many parts of the body and cause serious heal...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Cincinnati, Ohio, United States

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