Clinical Trials for Transthyretin Amyloidosis

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

NCT ID: NCT06563895

The ACT-EARLY Study is a clinical trial investigating a new experimental drug called acoramidis, aimed at preventing or delaying the onset of a serious condition known as transthyretin amyloidosis ...

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

NCT ID: NCT06465810

The MaesTTRo study is looking at patients with transthyretin amyloidosis (ATTR), a condition where abnormal proteins build up in the body, affecting various organs. This research aims to understand...

Retrospective Identification of Scintigraphic Cardiac Amyloidosis (RISCA)

NCT ID: NCT06921408

The RISCA trial is studying a condition called transthyretin cardiac amyloidosis, which affects the heart and can be difficult to diagnose. Researchers want to find out how effective a specific ima...

Myocardial Effects in Patients with ATTRv with Polyneuropathy Treated with Patisiran or Vutrisiran

NCT ID: NCT05873868

This clinical trial is investigating how two treatments, Patisiran and Vutrisiran, affect the heart in patients with a condition called hereditary transthyretin amyloidosis (ATTRv). This disease ca...

Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis

NCT ID: NCT05758493

This clinical trial is studying a medication called iodine-124 evuzumitide (also known as AT-01) in patients with a condition called systemic amyloidosis, specifically focusing on those with transt...

Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF

NCT ID: NCT05577819

This clinical trial is looking at how common a condition called transthyretin amyloidosis (ATTR) is in patients who have a specific type of heart failure known as Heart Failure with Preserved Eject...

PL_GNT01_ISR_Grant 53234273

NCT ID: NCT06714019

Evaluation of a Claims-based Algorithm for the Identification of Transthyretin-mediated Amyloidosis (ATTR) Amyloidosis in Medical Records

NCT ID: NCT04569903

This clinical trial is studying a new way to identify a condition called Transthyretin Amyloidosis (ATTR) using a special algorithm. The goal is to see how well this algorithm can find patients who...

New Biomarkers and Plasma Prothrombotic Potential in Cardiac Transthyretin Amyloidosis

NCT ID: NCT06345235

This clinical trial is studying a condition called Transthyretin Amyloidosis (ATTR), which affects the heart by causing harmful proteins to build up in heart tissue. Researchers want to learn more ...

Phenotyping and Characterization of wtATTR-CM (TRACE 1)

NCT ID: NCT06291805

The TRACE 1 clinical trial is studying a condition called wild-type transthyretin amyloidosis with cardiomyopathy (ATTRwt-CM), which affects the heart and can impact patients' quality of life. The ...

Prevalence of wtATTR-CM After Carpal Tunnel Release Surgery

NCT ID: NCT04276220

This clinical trial is studying the presence of a condition called wild-type transthyretin amyloidosis (wtATTR-CM) in older patients who are undergoing carpal tunnel release surgery. The researcher...