Clinical Trials for Ulcerative Colitis (UC)

Find clinical trials for ulcerative colitis (uc). Discover research opportunities and treatment options in your area.

46 Active Trials Found

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Evaluating the Shift From Intravenous to Subcutaneous Vedolizumab for Inflammatory Bowel Disease

NCT ID: NCT07123350

This study is looking at patients with inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, who are switching from receiving a medicine called vedolizumab through an ...

Not yet recruiting

Type: observational Locations: Nashville, Tennessee, United States

STOP-UC: De-escalation of Therapy in Patients With Ulcerative Colitis With Histological Remission

NCT ID: NCT06693310

The STOP-UC clinical trial is studying how to manage treatment for people with ulcerative colitis (UC), a condition that causes inflammation in the colon. The researchers want to find out if patien...

Not yet recruiting

Phase: NA Type: interventional Locations: Chicago, Illinois, United States

DYNAMIC-UC: Early qFIT and Calprotectin Change Predicting Relapse in Biologic-Naive Ulcerative Colitis

NCT ID: NCT07111273

This clinical trial is studying whether early changes in two stool tests—called qFIT and fecal calprotectin—can help predict if people with active ulcerative colitis (a long-term bowel condition) w...

Not yet recruiting

Type: observational Locations: Jinan, Shandong, China

TIDHI Mental Health in IBD Patients Study

NCT ID: NCT07013578

The TIDHI Mental Health in IBD Patients Study is looking to understand how a specific mental health support program called Healing Circuits™ can help individuals with inflammatory bowel disease (IB...

Recruiting

Phase: NA Type: interventional Locations: North York, Ontario, Canada

A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

NCT ID: NCT07113522

This clinical trial is studying new treatments for adults with moderate to severe inflammatory bowel disease (IBD), specifically Crohn’s Disease or Ulcerative Colitis. The main goal is to see how s...

Recruiting

Phase: PHASE2 Type: interventional Locations: Little Rock, Arkansas, United States, Miami, Florida, United States +14 more

Fecal biOmarker Response Evaluation for Super-Early Efficacy in Ulcerative Colitis

NCT ID: NCT07111572

This clinical trial is studying whether simple stool tests can help doctors see early on if a treatment is working for people with moderate-to-severe ulcerative colitis, a condition that causes inf...

Not yet recruiting

Type: observational

A First-in-Human Study of BB-TL1A-VIAL-HLE in Healthy Adults and People With Ulcerative Colitis

NCT ID: NCT07029971

This clinical trial is studying a new treatment called BB-TL1A-VIAL-HLE to see if it is safe for healthy adults and if it can help adults with moderate-to-severe ulcerative colitis, a condition tha...

Recruiting

Phase: PHASE1 Type: interventional Locations: Sydney, New South Wales, Australia, Warriewood, New South Wales, Australia

A Randomized Double-Blind, Placebo-Controlled Study of the Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of BCD-261 in Subjects With Moderate to Severe Active Ulcerative Colitis

NCT ID: NCT07080034

This clinical trial is studying a new medicine called BCD-261 to see if it can help adults with moderate to severe ulcerative colitis (UC), a condition that causes inflammation and sores in the lar...

Recruiting

Phase: PHASE2 Type: interventional Locations: Novosibirsk, , Russian Federation, Moscow, , Russian Federation +17 more

Safety and Efficacy of OD-07656 and of Subsequent Vedolizumab Therapy in Moderately to Severely Active Ulcerative Colitis

NCT ID: NCT06850727

This clinical trial is investigating a new medication called OD-07656 for people with moderately to severely active ulcerative colitis (UC), a condition that causes inflammation and ulcers in the l...

Recruiting

Phase: PHASE2 Type: interventional Locations: Melbourne, , Australia, Chisinau, , Moldova, Republic Of +2 more

A Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of ENC1018 Capsules in Patients With Moderate-to-severe Active Ulcerative Colitis (UC)

NCT ID: NCT07062185

This clinical trial is studying a new medicine called ENC1018 to see if it is safe and how it works in the body for people with moderate to severe ulcerative colitis (UC), a condition that causes i...

Not yet recruiting

Phase: NA Type: interventional

Evaluating the Efficacy and Safety of Mirikizumab in Adults Over 60 With Moderate to Severe Crohn's Disease and Ulcerative Colitis

NCT ID: NCT07059130

This clinical trial is studying a medicine called Mirikizumab to see how well it works and how safe it is for adults aged 60 and older who have moderate to severe Crohn’s disease or ulcerative coli...

Not yet recruiting

Phase: PHASE4 Type: interventional Locations: Lawrence, Massachusetts, United States

Selection and Efficacy-Influencing Factors of First-Line Biologic Agents in Moderate-to-Severe Ulcerative Colitis

NCT ID: NCT06962020

This clinical trial is designed to compare two first-line biologic treatments, Infliximab (IFX) and Vedolizumab (VDZ), for patients with moderate to severe ulcerative colitis (UC). The main goal is...

Recruiting

Type: observational Locations: Shanxi, Xi'an, China

Smart Pill for Measuring Gut Health in Colon Inflammation and Colon Cancer

NCT ID: NCT07046468

This clinical trial is studying a new “smart pill” that can be swallowed to help measure changes inside the gut for people with ulcerative colitis (a type of long-term bowel inflammation) or colore...

Not yet recruiting

Type: observational Locations: Nijmegen, Gelderland, Netherlands

Assessing Interventions of Diet in IBD

NCT ID: NCT06773182

This clinical trial is looking at how different diets can impact people with inflammatory bowel disease (IBD), which includes conditions like ulcerative colitis and Crohn's disease. Researchers wan...

Recruiting

Phase: NA Type: interventional Locations: Hamilton, Ontario, Canada, Hamilton, Ontario, Canada

Impact of the Novel UC-TREAT Diet on the Gut Microbiome and Its Acceptability in Healthy Adults and Adults With Quiescent Ulcerative Colitis

NCT ID: NCT06998277

This clinical trial is studying the effects of a new diet called the UC-TREAT diet on the gut microbiome, which is the community of bacteria in our intestines. The trial involves both healthy adult...

Recruiting

Phase: NA Type: interventional Locations: Glasgow, , United Kingdom

Efficacy and Safety of Discontinuing 5-ASA in Patients With Inflammatory Bowel Disease

NCT ID: NCT06878495

This clinical trial is exploring whether stopping a medication called 5-ASA (mesalamine) is safe for patients with inflammatory bowel disease (IBD), which includes conditions like ulcerative coliti...

Not yet recruiting

Phase: NA Type: interventional

Multi-omics Dissection of Gut Microbiome Engraftment During FMT

NCT ID: NCT06992453

This clinical trial is studying how the gut microbiome, which is the collection of bacteria and other microorganisms in our intestines, affects the success of fecal microbiota transplantation (FMT)...

Not yet recruiting

Phase: NA Type: interventional Locations: Rome, Rm, Italy

hucMSCs Exosomes for the Treatment of Active Ulcerative Colitis

NCT ID: NCT06853522

This clinical trial is looking at a new treatment for people with active ulcerative colitis (UC), which is a condition that causes inflammation in the colon. The study will test the safety and effe...

Not yet recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Shanghai, Shanghai, China

Therapeutic Drug Monitoring for Biological Therapy in Pediatric Inflammatory Bowel Disease

NCT ID: NCT06954311

This clinical trial is investigating how certain medications, known as biologics, work in children with Inflammatory Bowel Disease (IBD), specifically those diagnosed with ulcerative colitis or IBD...

Recruiting

Type: observational Locations: Villach, , Austria, Feldkirch, , Austria +8 more

A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Newly Diagnosed Active Ulcerative Colitis

NCT ID: NCT06895252

This clinical trial is studying how fecal microbiota transplantation (FMT) and dietary changes can help people with newly diagnosed active ulcerative colitis (UC), a condition that causes inflammat...

Recruiting

Phase: NA Type: interventional Locations: Kochi, Kerala, India, Mumbai, Maharashtra, India +5 more

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