Clinical Trials for Uveal Melanoma

Find clinical trials for uveal melanoma. Discover research opportunities and treatment options in your area.

29 Active Trials Found

Showing 29 trials on this page

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Adjuvant Tebentafusp in High Risk Ocular Melanoma

NCT ID: NCT06246149

This clinical trial is studying a new treatment called tebentafusp for patients with high-risk uveal melanoma, a type of eye cancer. The goal is to see if this treatment can help prevent the cancer...

Recruiting

Phase: PHASE3 Type: interventional Locations: Brussels, , Belgium, Berlin, , Germany +5 more

Neoadjuvant Darovasertib in Primary Uveal Melanoma

NCT ID: NCT07015190

This clinical trial is studying a new treatment called darovasertib for patients with primary uveal melanoma, which is a type of eye cancer that has not spread to other parts of the body. The trial...

Not yet recruiting

Phase: PHASE3 Type: interventional

Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma

NCT ID: NCT05524935

This clinical trial is studying a new treatment approach for advanced uveal melanoma, a type of eye cancer. Researchers are combining two medications: olaparib, which helps repair damaged DNA in ca...

Recruiting

Phase: PHASE2 Type: interventional Locations: Tampa, Florida, United States

Identification of New Candidate Genes for Hereditary Predisposition to Uveal Melanoma

NCT ID: NCT06550674

This clinical trial is focused on finding new genetic causes of uveal melanoma, a type of eye cancer. Currently, only 20% of families with a history of this cancer can trace it back to known inheri...

Recruiting

Phase: NA Type: interventional Locations: Clermont Ferrand, , France, Clermont Ferrand, Puy De Dôme, France

A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit

NCT ID: NCT06805825

This clinical trial is studying a new medication called NN3201, which is designed to treat patients with advanced or metastatic solid tumors that express a protein called c-Kit. These tumors can in...

Recruiting

Phase: PHASE1 Type: interventional Locations: Portland, Oregon, United States, Houston, Texas, United States +3 more

Adjuvant Quisinostat in High-Risk Uveal Melanoma

NCT ID: NCT06932757

This clinical trial is studying a medication called quisinostat to see if it can help prevent uveal melanoma, a type of eye cancer, from spreading in patients who are at high risk. The researchers ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Miami, Florida, United States

Adjuvant Melatonin for Uveal Melanoma

NCT ID: NCT05502900

This clinical trial is studying whether taking Melatonin after a diagnosis of uveal melanoma (a type of eye cancer) can help prevent or delay the spread of the disease to other parts of the body. U...

Recruiting

Phase: PHASE3 Type: interventional Locations: Stockholm, , Sweden

A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, or Dedifferentiated Liposarcoma

NCT ID: NCT05607095

This clinical trial is studying a new treatment called lifileucel (also known as LN-144) for patients with advanced forms of uveal melanoma, undifferentiated pleomorphic sarcoma, or dedifferentiate...

Recruiting

Phase: PHASE1 Type: interventional Locations: Harrison, New York, United States, New York, New York, United States +1 more

A Randomised Phase II Study of Roginolisib in Patients With Advanced/Metastatic Uveal Melanoma

NCT ID: NCT06717126

This clinical trial, titled "Study of Roginolisib in UM Patients," is investigating a new treatment called roginolisib for adults with uveal melanoma, a type of eye cancer. The main goals of the st...

Recruiting

Phase: PHASE2 Type: interventional Locations: Madrid, , Spain, London, , United Kingdom +14 more

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma

NCT ID: NCT06007690

This clinical trial is studying a new treatment called belzupacap sarotalocan (bel-sar) for patients with early-stage eye conditions known as primary indeterminate lesions or small choroidal melano...

Recruiting

Phase: PHASE3 Type: interventional Locations: Atlanta, Georgia, United States, Chicago, Illinois, United States +71 more

A Phase 1/2 Study of [225Ac]-FPI-1434 Injection

NCT ID: NCT03746431

This clinical trial is studying a new treatment called [225Ac]-FPI-1434 Injection for patients with advanced solid tumors, including types like endometrial, cervical, ovarian, and breast cancers. T...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Adelaide, South Australia, Australia +15 more

Gene Modified Immune Cells (IL13Ralpha2 CAR T Cells) After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

NCT ID: NCT04119024

This clinical trial is testing a new treatment for patients with advanced melanoma and other types of solid tumors that have spread in the body. The treatment involves using specially modified immu...

Recruiting

Phase: PHASE1 Type: interventional Locations: Duarte, California, United States, Los Angeles, California, United States +1 more

Tebentafusp in HLA-A*0201 Positive Previously Untreated Metastatic Uveal Melanoma

NCT ID: NCT06070012

This clinical trial is studying a new treatment called tebentafusp for patients with metastatic uveal melanoma, a type of eye cancer that has spread to other parts of the body. The trial is specifi...

Recruiting

Phase: PHASE2 Type: interventional Locations: Pittsburgh, Pennsylvania, United States

Prospective Registration Of Patient Data and Quality of Life in Eye Melanoma Patients

NCT ID: NCT05377957

The PROQEM trial is a study that aims to understand how living with uveal melanoma, a type of eye cancer, affects patients' quality of life both before and for five years after they receive treatme...

Recruiting

Type: observational Locations: Leiden, , Netherlands, Leiden, South Holland, Netherlands

Targeted Alpha Particle Radiotherapy for Metastatic Uveal Melanoma

NCT ID: NCT05496686

This clinical trial is exploring a new treatment called targeted alpha particle radiotherapy using a substance known as 225Ac-MTI-201 for patients with metastatic uveal melanoma, a type of eye canc...

Recruiting

Phase: PHASE1 Type: interventional Locations: Tampa, Florida, United States

Follow-up of Patients With Uveal Melanoma Adapted to the Risk of Relapse (SALOME)

NCT ID: NCT04424719

The SALOME trial is studying how to better follow up with patients who have uveal melanoma, a type of eye cancer, by looking for specific markers in their blood. These markers can help doctors iden...

Recruiting

Phase: NA Type: interventional Locations: Paris, , France

Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

NCT ID: NCT04792463

This clinical trial is studying a genetic condition called BAP1 Hereditary Predisposition Syndrome, which can increase the risk of several types of cancer, including uveal melanoma (a type of eye c...

Recruiting

Type: observational Locations: Columbus, Ohio, United States

PHP in Combination With IPI1/NIVO3 Compared to IPI3/NIVO1 Only in Patients With Uveal Melanoma Liver Metastases

NCT ID: NCT06519266

This clinical trial is studying a new treatment approach for patients with uveal melanoma that has spread to the liver. Uveal melanoma is a type of eye cancer, and when it spreads, it often leads t...

Recruiting

Phase: PHASE3 Type: interventional Locations: Uppsala, , Sweden, Gothenburg, , Sweden +4 more

(Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma

NCT ID: NCT05907954

This clinical trial is studying a medication called IDE196 (darovasertib) for patients with localized uveal melanoma, a type of eye cancer. The goal is to see how effective this treatment is when g...

Recruiting

Phase: PHASE2 Type: interventional Locations: Durham, North Carolina, United States, Rochester, Minnesota, United States +41 more

A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

NCT ID: NCT03611868

This clinical trial is investigating a new treatment called APG-115 for patients with advanced melanoma or other solid tumors that cannot be surgically removed. APG-115 works by blocking a protein ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Saint Louis, Missouri, United States, Durham, North Carolina, United States +20 more

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