Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1- Mediated Proteinuric Kidney Disease

NCT ID: NCT05312879

This clinical trial is studying a new treatment called VX-147 for patients with a specific type of kidney disease known as APOL1-mediated proteinuric kidney disease. This condition can lead to prot...

Recruiting

Phase: PHASE2 Conditions: Proteinuric Kidney Disease

A Study to Examine the Efficacy and Safety of Zanubrutinib Given to Adults With Primary Membranous Nephropathy

NCT ID: NCT05707377

This clinical trial is studying a medication called zanubrutinib to see how safe and effective it is for treating a kidney condition known as primary membranous nephropathy. The trial is divided in...

Recruiting

Phase: PHASE2 Conditions: Primary Membranous Nephropathy

Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

NCT ID: NCT06855498

This clinical trial is a continuation study for people who have already participated in earlier studies involving a medication called povorcitinib, which is being tested for a skin condition known ...

Recruiting

Phase: PHASE3 Conditions: Hidradenitis Suppurativa (HS)

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis

NCT ID: NCT05485961

This clinical trial is studying a medication called CSL300 (Clazakizumab) to see if it can help improve heart health for adults with end-stage kidney disease (ESKD) who are undergoing dialysis. The...

Recruiting

Phase: PHASE2 Conditions: Atherosclerotic Cardiovascular Disease, End Stage Kidney Disease +1 more

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)

NCT ID: NCT05692180

The DOMINICA study is a clinical trial designed to evaluate the effectiveness and safety of a medication called benralizumab for children and teenagers aged 6 to 17 years who suffer from severe eos...

Recruiting

Phase: PHASE3 Conditions: Asthma

Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)

NCT ID: NCT06958211

This clinical trial is studying a new cream called ruxolitinib to see how well it works and how safe it is for people with hidradenitis suppurativa (HS). HS is a chronic skin condition that causes ...

Recruiting

Phase: PHASE3 Conditions: Hidradenitis Suppurativa

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

NCT ID: NCT06935370

This clinical trial is studying whether a medication called vicadrostat, when combined with another medication called empagliflozin, can help people with heart failure. Heart failure occurs when th...

Recruiting

Phase: PHASE3 Conditions: Heart Failure

Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

NCT ID: NCT06605378

This clinical trial is looking at the levels of specific antibodies and inflammatory substances called cytokines in men, both adults and children, who have Chronic Granulomatous Disease (CGD). CGD ...

Recruiting

Conditions: Chronic Granulomatous Disease (CGD)

Observational Evaluation of Atopic Dermatitis in Pediatric Patients

NCT ID: NCT03687359

This clinical trial is looking at children and teenagers with moderate to severe atopic dermatitis (AD), a skin condition that can cause red, itchy patches. The goal is to understand more about the...

Recruiting

Conditions: Dermatitis Atopic

Manipulation and Dry Needling in Patients With Cervicogenic Headache and WAD II

NCT ID: NCT06502951

This clinical trial is exploring two different treatment methods for people suffering from cervicogenic headaches, which are headaches caused by neck problems, often linked to whiplash injuries fro...

Recruiting

Phase: NA Conditions: Cervicogenic Headache, Whiplash Injuries

Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA

NCT ID: NCT04955795

This clinical trial is looking at how effective a combination of two types of treatments can be for individuals living with HIV who have unhealthy alcohol use. Specifically, the study will compare ...

Recruiting

Phase: NA Conditions: Hiv, Alcohol Problem

A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma

NCT ID: NCT06023589

This clinical trial is studying a medication called tezepelumab to see how well it works and how safe it is for children aged 5 to under 12 years who have severe asthma that isn't well controlled. ...

Recruiting

Phase: PHASE3 Conditions: Asthma

Characterization And Clinical Outcomes of AA Patients Treated With Ritlecitinib

NCT ID: NCT06531109

This clinical trial is studying the effectiveness of a medication called ritlecitinib for treating alopecia areata (AA), a condition that causes hair loss on the scalp and other areas of the body. ...

Recruiting

Conditions: Alopecia Areata

Combining a Smartphone App With Medications to Manage Heavy Drinking

NCT ID: NCT06303778

This clinical trial is studying the effectiveness of using a smartphone app along with medications to help Veterans manage heavy drinking, specifically those diagnosed with Alcohol Use Disorder (AU...

Recruiting

Phase: NA Conditions: Alcohol Use Disorder (AUD)

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

NCT ID: NCT05011383

This clinical trial is exploring whether high doses of testosterone can help men with certain types of advanced prostate cancer that have specific genetic changes. The focus is on patients whose ca...

Recruiting

Phase: PHASE2 Conditions: Metastatic Prostate Cancer

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Clinical Trials in Montgomery, Alabama

15 Active Trials Found in Montgomery

Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1- Mediated Proteinuric Kidney Disease

A Study to Examine the Efficacy and Safety of Zanubrutinib Given to Adults With Primary Membranous Nephropathy

Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)

Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

Observational Evaluation of Atopic Dermatitis in Pediatric Patients

Manipulation and Dry Needling in Patients With Cervicogenic Headache and WAD II

Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA

A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma

Characterization And Clinical Outcomes of AA Patients Treated With Ritlecitinib

Combining a Smartphone App With Medications to Manage Heavy Drinking

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers