Clinical Trials in Hefei, Anhui

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

NCT ID: NCT03486873

This clinical trial, called MK-3475-587, is looking into the long-term safety and effectiveness of a treatment called pembrolizumab (also known as MK-3475) for patients with advanced tumors. If you...

Pan Tumor Rollover Study

NCT ID: NCT03899155

The Pan Tumor Rollover Study is a clinical trial focused on understanding the long-term safety of a cancer treatment called nivolumab, both on its own and in combination with other therapies. This ...

Study of Tislelizumab, Pamiparib, and Other Investigational Agents in Participants With Advanced Malignancies

NCT ID: NCT04164199

Study of Pembrolizumab (MK-3475) Monotherapy Versus Sacituzumab Govitecan in Combination With Pembrolizumab for Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-3475-D46)

NCT ID: NCT05609968

This clinical trial is studying two different treatment options for adults with metastatic non-small cell lung cancer (NSCLC) that has a specific marker called PD-L1, which is found in at least 50%...

A Study of BGB-16673 Compared to Investigator's Choice in Participants With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Covalent Bruton Tyrosine Kinase (BTK) Inhibitors

NCT ID: NCT06970743

This clinical trial is studying a new treatment called BGB-16673 for patients with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). These are types of ...

A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

NCT ID: NCT07043400

This clinical trial is studying a cancer treatment called tislelizumab for adults with advanced stomach cancer or cancer where the stomach meets the esophagus. The goal is to compare two ways of gi...

Safety and Efficacy of Metabolically Armed BCMA CAR-T Cells (Meta10-BCMA) in the Treatment of r/r Plasma Cell Neoplasms Clinical Research

NCT ID: NCT07085559

This clinical trial is testing a new treatment called Meta10-BCMA CAR-T cell therapy for people with certain blood cancers, including multiple myeloma, plasma cell leukemia, and AL amyloidosis, esp...

A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001)

NCT ID: NCT06052059

This clinical trial is studying a new medication called tulisokibart (MK-7240) to see if it is effective and safe for people with moderately to severely active ulcerative colitis, a condition that ...

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

NCT ID: NCT06136559

This clinical trial is studying a new medication called nemtabrutinib (MK-1026) to see how it compares to two existing treatments, ibrutinib and acalabrutinib, for patients with chronic lymphocytic...

Efficacy And Safety Of MK-6194 In Adult Participants With Systemic Lupus Erythematosus (MK-6194-006)

NCT ID: NCT06161116

This clinical trial is studying a new treatment called MK-6194 for adults with Systemic Lupus Erythematosus (SLE), a condition where the immune system mistakenly attacks healthy tissues. The main g...

A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

NCT ID: NCT06764485

This clinical trial is looking at a new treatment called BMS-986365 for men with metastatic castration-resistant prostate cancer, which means their cancer has spread beyond the prostate and is no l...

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

NCT ID: NCT06875310

The KRYSTAL-4 trial is studying a new treatment approach for patients with a specific type of lung cancer called non-small cell lung cancer (NSCLC) that has a mutation known as KRAS G12C. This tria...

A Phase I Study of SNH-119014 in Healthy Volunteers

NCT ID: NCT07087262

This clinical trial is testing a new oral medicine called SNH-119014, which is being developed to help treat certain blood disorders where red blood cells break down too quickly (called hemolytic a...

A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

NCT ID: NCT04928846

This clinical trial is studying a new treatment called telisotuzumab vedotin for adults with non-small cell lung cancer (NSCLC) who have already received treatment in the past. Researchers want to ...

A Study to Evaluate Mezigdomide in Combination With Carfilzomib and Dexamethasone (MeziKD) Versus Carfilzomib and Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (SUCCESSOR-2)

NCT ID: NCT05552976

The SUCCESSOR-2 trial is studying a new treatment for patients with relapsed or refractory multiple myeloma, a type of blood cancer. This trial is comparing a combination of three medications: Mezi...

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

NCT ID: NCT06292013

The ACCLAIM-Lp(a) trial is studying a new treatment called lepodisiran to see if it can help reduce the risk of serious heart problems in adults who have high levels of a substance called lipoprote...

Evaluation of Efficacy of Povetacicept in Adults With Immunoglobulin A Nephropathy (IgAN)

NCT ID: NCT06564142

This clinical trial is studying a new medication called povetacicept for adults with Immunoglobulin A Nephropathy (IgAN), a condition that affects the kidneys and can lead to kidney damage. The mai...

A Study of Remternetug (LY3372993) in Early Alzheimer's Disease (TRAILRUNNER-ALZ 3)

NCT ID: NCT06653153

The TRAILRUNNER-ALZ 3 study is looking at a new drug called Remternetug (LY3372993) to see if it can help people with early Alzheimer's disease. The main goal of the trial is to find out if this dr...

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

NCT ID: NCT06890598

This clinical trial is studying a new treatment called olomorasib, which is being tested alongside standard treatments for patients with a specific type of lung cancer known as KRAS G12C-mutant non...

A Study Comparing BMS-986504 in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)

NCT ID: NCT07076121

This clinical trial is studying a new treatment option for people with a type of advanced pancreatic cancer called metastatic pancreatic ductal adenocarcinoma (PDAC). Specifically, it’s looking at ...