Clinical Trials in Edegem, Antwerpen

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

NCT ID: NCT06890598

This clinical trial is studying a new treatment called olomorasib, which is being tested alongside standard treatments for patients with a specific type of lung cancer known as KRAS G12C-mutant non...

Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab

NCT ID: NCT06107413

This clinical trial is studying a new treatment for adults with unresectable metastatic colorectal cancer, which means their cancer cannot be surgically removed and has spread to other parts of the...

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

NCT ID: NCT06292013

The ACCLAIM-Lp(a) trial is studying a new treatment called lepodisiran to see if it can help reduce the risk of serious heart problems in adults who have high levels of a substance called lipoprote...

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

NCT ID: NCT06365853

This clinical trial is investigating the safety and effects of a new treatment called mirvetuximab soravtansine (MIRV) for women with recurrent ovarian cancer that expresses high levels of a protei...

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)

NCT ID: NCT06383390

The TRIUMPH-OUTCOMES study is looking at a new treatment called retatrutide, which is given once a week, to see if it can help reduce serious heart problems and protect kidney function in adults wh...

A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

NCT ID: NCT04928846

This clinical trial is studying a new treatment called telisotuzumab vedotin for adults with non-small cell lung cancer (NSCLC) who have already received treatment in the past. Researchers want to ...

A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

NCT ID: NCT06072781

This clinical trial is looking at a new treatment for women with recurrent low-grade serous ovarian cancer (LGSOC), which means the cancer has come back after previous treatments. The study is test...

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

NCT ID: NCT06282575

This clinical trial is investigating a new treatment approach for patients with advanced biliary tract cancer that has a specific gene mutation called HER2. The study is looking at how effective an...

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

NCT ID: NCT06312137

This clinical trial is investigating whether a combination of two treatments, pembrolizumab and sacituzumab tirumotecan, can help patients with a type of lung cancer called non-small cell lung canc...

An Extension Study of the Long-Term Safety, Tolerability, and Efficacy of Tividenofusp Alfa (DNL310) in Participants With Mucopolysaccharidosis Type II (MPS II) From Study DNLI-E-0002 or Study DNLI-E-0007

NCT ID: NCT06075537

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

NCT ID: NCT06077760

This clinical trial is looking at a new treatment combination for patients with non-small cell lung cancer (NSCLC) who have had surgery to remove their cancer. The study compares the effects of a d...

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

NCT ID: NCT04844606

The AMAZ trial is a clinical study looking at the long-term effects of a medication called mirikizumab in children and teenagers with ulcerative colitis (UC) or Crohn's disease (CD). This study is ...

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

NCT ID: NCT05711394

This clinical trial is studying a medication called atogepant to see how safe and effective it is for treating episodic migraines in children aged 6 to 17. Migraines are severe headaches that can c...

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

NCT ID: NCT04613596

The KRYSTAL-7 trial is studying a new treatment for patients with advanced non-small cell lung cancer (NSCLC) that has a specific mutation called KRAS G12C. The trial has two parts: the Phase 2 par...

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

NCT ID: NCT06561386

This clinical trial is studying two different treatments for patients with stage IV or recurrent non-squamous non-small cell lung cancer, specifically those whose tumors have a certain level of PD-...

A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease

NCT ID: NCT05995353

This clinical trial is studying a medication called risankizumab, which is designed to help children and teenagers with moderately to severely active Crohn's Disease (CD). Crohn's Disease can cause...

A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

NCT ID: NCT04557462

This clinical trial is studying a drug called iptacopan, which is being tested for its long-term safety and tolerability in people with a kidney condition known as primary IgA nephropathy. Particip...

Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia

NCT ID: NCT04579367

This clinical trial is investigating the use of a medication called bempedoic acid and its combination with another drug, ezetimibe, for patients with high cholesterol levels. Specifically, it focu...

Study of Oral Atogepant Tablets to Assess Safety and Efficacy in Adult Participants With Migraine

NCT ID: NCT06241313

This clinical trial is studying a medication called atogepant, which is taken as a tablet, to see how well it works and how safe it is for adults who experience migraine attacks. Migraines are seve...

A Study to Test How Safe Pozelimab and Cemdisiran Combination Therapy and Cemdisiran Alone Are and How Well They Work in Adult Patients With Generalized Myasthenia Gravis

NCT ID: NCT05070858

This clinical trial is testing a new treatment option for adults with generalized myasthenia gravis (gMG), a condition that causes muscle weakness and fatigue due to communication issues between ne...